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Infectious Disease: SARS

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Total 1917 results found since Jan 2013.

Clinical course and outcomes in patients with asthma hospitalized for SARS-CoV-2 pneumonia:a single-center, retrospective study.
The data on the clinical characteristics and outcomes of asthmatics with SARS-CoV-2 infection are scarce, but are of paramount importance to evaluate the relationship between COVID-19 and asthma. Given the characteristics of the virus, one would expect to observe an increased prevalence of asthma and wheezing exacerbations in COVID-19 patients with allergy and asthma comorbidity, a typical consequence in case of a viral respiratory infection (1). In this single-centre, observational study, we investigated asthmatic patients with confirmed SARS-CoV-2 pneumonia who were admitted to our hospital (Fondazione Poliambulanza Isti...
Source: Annals of Allergy, Asthma and Immunology - July 30, 2020 Category: Allergy & Immunology Authors: Carlo Lombardi, Elena Roca, Barbara Bigni, Marcello Cottini, Giovanni Passalacqua Tags: Letters Source Type: research

Children and adolescents with allergy and/or asthma seem to be protected from coronavirus disease 2019
Akenroye et  al1 discussed the use of corticosteroids and biologics in asthma during coronavirus disease 2019 (COVID-19) pandemic. COVID-19 began in the People's Republic of China and rapidly spread worldwide.2 Italy was the first European country involved in the pandemic and the first cluster occurring in Sou th Lombardy. The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), penetrates the host cells binding to the angiotensin-converting enzyme 2 (ACE2) receptors.
Source: Annals of Allergy, Asthma and Immunology - August 26, 2020 Category: Allergy & Immunology Authors: Giorgio Ciprandi, Amelia Licari, Gaetana Filippelli, Maria Angela Tosca, Gian Luigi Marseglia Tags: Correspondence Source Type: research

Age-Related differences in immunological responses to SARS-CoV-2
Publication date: Available online 27 August 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Lydia Su Yin Wong, Evelyn Xiu Ling Loo, Alicia Yi Hui Kang, Hui Xing Lau, Paul Anantharajah Tambyah, Elizabeth Huiwen Tham
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 28, 2020 Category: Allergy & Immunology Source Type: research

SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts
Publication date: Available online 21 September 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): George Makedonas, Satish K. Mehta, Richard A. Scheuring, Robert Haddon, Brian E. Crucian
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2020 Category: Allergy & Immunology Source Type: research

Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection
Publication date: January 2021Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 9, Issue 1Author(s): Doriane Calmes, Sophie Graff, Nathalie Maes, Anne-Noëlle Frix, Marie Thys, Olivier Bonhomme, Julien Berg, Mathieu Debruche, Fanny Gester, Monique Henket, Virginie Paulus, Bernard Duysinx, Vincent Heinen, Delphine Nguyen Dang, Astrid Paulus, Valérie Quaedvlieg, Frederique Vaillant, Hélène Van Cauwenberge, Michel Malaise, Alisson Gilbert
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 6, 2021 Category: Allergy & Immunology Source Type: research

High frequency of smell and taste dysfunctions in allergy health care professionals suffering from COVID-19.
CONCLUSIONS: STD is a common symptom in COVID-19, even as a unique or preceding symptom. HCP who declared smell dysfunction (SD) were younger than those not affected with STD. Taste dysfunction (TD) may imply more systemic involvement in COVID-19-positive HCP. PMID: 33465033 [PubMed - as supplied by publisher]
Source: Journal of Investigational Allergology and Clinical Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Amérigo DA, Cubero JL, Colás C, Alobid I, Mullol J, Valero A Tags: J Investig Allergol Clin Immunol Source Type: research

SARS-CoV-2-Associated T-Cell Responses in the Presence of Humoral Immunodeficiency
We report perhaps the most comprehensive study of subsets of CD4+ and CD8+ and subsets of B cells in a mild symptomatic SARS-CoV-2+ immunocompetent patient and a common variable immunodeficiency disease (CVID) patient who had normal absolute lymphocyte counts and remained negative for SARS-CoV-2 IgG antibodies. Na ïve (TN), central memory (TCM), effector memory (TEM), and terminally differentiated effector memory (TEMRA) subsets of CD4+ and CD8+ T cells, subsets of T follicular helper cells (cTFH, TFH1, TFH2, TFH17, TFH1/TFH17, and TFR), CD4 Treg, CD8 Treg, mature B cells, transitional B cells, marginal zone B cells, germ...
Source: International Archives of Allergy and Immunology - January 22, 2021 Category: Allergy & Immunology Source Type: research

Insights from American College of Allergy, Asthma, and Immunology COVID-19 Vaccine Task Force: Allergic Reactions to mRNA SARS-CoV-2 Vaccines: Allergic Reactions to mRNA SARS-CoV-2 Vaccines
Allergic reactions to vaccines, in general, are rare with the incidence of anaphylaxis estimated at 1.31 in 1 million doses given (1). Recent immediate allergic reactions clinically compatible with anaphylaxis have occurred in recipients of both the Pfizer-BioNTech and Moderna mRNA SARS-CoV-2 (CoV-2 or COVID) vaccines. Currently the specific mechanism(s) and inciting antigen/agent(s) have not been identified.
Source: Annals of Allergy, Asthma and Immunology - January 22, 2021 Category: Allergy & Immunology Authors: Kevin R. Murphy, Niraj C. Patel, Daniel Ein, Mary Hudelson, Sangeetha Kodoth, Gailen D. Marshall, Purvi Parikh, Michael S. Blaiss Tags: Perspective Source Type: research

Effect of Patient and Parental Anxiety on Adherence to Subcutaneous Allergen Immunotherapy During COVID-19 Pandemic
The global spread of SARS-CoV-2 has resulted in over a million deaths to date, despite many strategies implemented to limit transmission, such as social distancing, wearing face mask and quarantining/isolation1,2.These strategies were also applied in health care facilities, including recommendations for minimizing face-to-face meetings in allergy and immunology clinics and taking necessary precautions to minimize the risk of transmission3.
Source: Annals of Allergy, Asthma and Immunology - January 22, 2021 Category: Allergy & Immunology Authors: Ilknur Kulhas Celik, Azize Pinar Metbulut, Ozden Sukran Uneri, Gulser Senses Dinc, Emine Dibek Misirlioglu Tags: Letters Source Type: research

Principles and Challenges in anti-COVID-19 Vaccine Development
The number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients keeps rising in most of the European countries despite the pandemic precaution measures. The current antiviral and anti-inflammatory therapeutic approaches are only supportive, have limited efficacy, and the prevention in reducing the transmission of SARS-CoV-2 virus is the best hope for public health. It is presumed that an effective vaccination against SARS-CoV-2 infection could mobilize the innate and adaptive immune responses and provide a protection against severe forms of coronavirus disease 2019 (COVID-19) disease. As the ra...
Source: International Archives of Allergy and Immunology - February 1, 2021 Category: Allergy & Immunology Source Type: research

Analysis Of COVID-19 In Adult Asthmatic Outpatients
During the SARS-CoV-2 pandemic, the Infanta Leonor University Hospital (Madrid, Spain) was one of the most affected, assisting 2,968 COVID-19 patients (March-April 2020). Our aim was to analyse the epidemiological and clinical characteristics of COVID-19 in adult asthmatic outpatients in our allergy unit.
Source: Journal of Allergy and Clinical Immunology - February 1, 2021 Category: Allergy & Immunology Authors: Maria Somoza Alvarez, Ana Mar Ãa Prieto-Moreno Pfeifer, Isabel Torres Rojas, Maria Desamparados Cervera, Diana Perez-Alzate, Maria Vazquez de La Torre, Elisa Haroun-Diaz, Francisco Javier Ruano, Paula Lopez-Gonzalez, Natalia Blanca-Lopez, Gabriela Canto Source Type: research

The Impact of the SARS-CoV-2 Pandemic on the Emergency Department and Management of the Pediatric Asthmatic Patient
Source: Journal of Asthma and Allergy - February 3, 2021 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Quantitative Measurement of IgG to Severe Acute Respiratory Syndrome Coronavirus-2 Proteins Using ImmunoCAP
Conclusions: We have described a quantitative assay to measure IgG to SARS-CoV-2 that could be used in clinical and research laboratories and implemented at scale. The assay can easily be adapted to measure IgG to mutated COVID-19 proteins, has good performance characteristics, and has a readout in standardized units.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - February 23, 2021 Category: Allergy & Immunology Source Type: research

COVID-19 Associated Multisystem Inflammatory Syndrome: A Systematic Review and Meta-analysis
This study was aimed to describe clinical manifestation and outcomes of MIS-C associated with COVID-19. This systematic review and meta-analysis were conducted on all available literature until July 3rd, 2020. The screening was done by using the following keywords: ("novel coronavirus" Or COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus) and ("MIS-C" or "multisystem inflammatory" or Kawasaki). Data on gender, ethnicity, clinical presentations, need for mechanical ventilation or admission to intensive care unit (ICU), imaging, cardiac complications, and COVID-19 laboratory results were...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Ashkan Baradaran Abdolreza Malek Nasrin Moazzen Zahra Abbasi Shaye Source Type: research

Prevalence of SARS-CoV-2 in Patients with Severe Pneumonia in Khuzestan Province, Iran
This study aimed to evaluate the frequency of SARS-CoV-2 in hospitalized patients with an acute respiratory infection (ARI). During an outbreak of the SARS-CoV-2, the nasopharyngeal and oropharyngeal swabs were collected from 909 hospitalized patients with severe pneumonia, including 517 (56.9%) males and 392 (43.1%) females. All the collected samples were from different cities of Khuzestan province from 19 February to- 27 March 2020. The RNA was extracted from samples and subjected to real-time polymerase chain reaction (PCR) tests for the detection of the SARS-CoV-2. Simultaneously, the computerized tomography (CT) scan ...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Farhad Abolnezhadian Manoochehr Makvandi Seyed Mohammad Alavi Azarakhsh Azaran Shahram Jalilian Mohammad Rashno Gholam Abbas Kaydani Maniya Arshadi Seyed Mehdi Hosseinizadeh Hatam Boostani Seyed Saeed Seyedian Sasan Moogahi Shokrolah Salmanzadeh Mehran Va Source Type: research