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Virus Control of Cell Metabolism for Replication and Evasion of Host Immune Responses
María Maximina B. Moreno-Altamirano1*, Simon E. Kolstoe2 and Francisco Javier Sánchez-García1* 1Laboratorio de Inmunorregulación, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico 2School of Health Sciences, University of Portsmouth, Portsmouth, United Kingdom Over the last decade, there has been significant advances in the understanding of the cross-talk between metabolism and immune responses. It is now evident that immune cell effector function strongly depends on the metabolic pathw...
Source: Frontiers in cellular and infection microbiology - April 17, 2019 Category: Microbiology Source Type: research

What Infectious Diseases are Important to Consider in Transplantation Patients?
Discussion Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - June 24, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Anti-infectious human vaccination in historical perspective.
Authors: D'Amelio E, Salemi S, D'Amelio R Abstract A brief history of vaccination is presented since the Jenner's observation, through the first golden age of vaccinology (from Pasteur's era to 1938), the second golden age (from 1940 to 1970), until the current period. In the first golden age, live, such as Bacille Calmette Guérin (BCG), and yellow fever, inactivated, such as typhoid, cholera, plague, and influenza, and subunit vaccines, such as tetanus and diphtheria toxoids, have been developed. In the second golden age, the cell culture technology enabled polio, measles, mumps, and rubella vaccines be developed...
Source: International Reviews of Immunology - February 17, 2016 Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research

How Hepatitis Became A Hidden Epidemic In Africa
This article was originally published on The Conversation. Read the original article. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - March 10, 2017 Category: Consumer Health News Source Type: news

Anti-Infectious Human Vaccination in Historical Perspective.
Authors: D'Amelio E, Salemi S, D'Amelio R Abstract A brief history of vaccination is presented since the Jenner's observation, through the first golden age of vaccinology (from Pasteur's era to 1938), the second golden age (from 1940 to 1970), until the current period. In the first golden age, live, such as Bacille Calmette Guérin (BCG), and yellow fever, inactivated, such as typhoid, cholera, plague, and influenza, and subunit vaccines, such as tetanus and diphtheria toxoids, have been developed. In the second golden age, the cell culture technology enabled polio, measles, mumps, and rubella vaccines be developed...
Source: International Reviews of Immunology - January 30, 2018 Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research

Intermittent rash, lymph node swelling, arthralgia and vaccinal viral detection after rubella immunization
A 26-year-old woman was immunized on August 2008 with the rubella/measles vaccine (MR, Serum Institute of India). She had been in good health previously, with no medical history of any rheumatologic affection. The patient had already been vaccinated against rubella two years before, in an immunization campaign that occurred in Brazilian the state of São Paulo, and had no adverse reactions. She inadvertently took the vaccine again in the national campaign in 2008. Five days after the most recent vaccination, she developed fever, retroauricular lymph node swelling, erythematous maculopapular rash on her trunk, back, abdomen...
Source: Journal of Clinical Virology - August 20, 2012 Category: Virology Authors: Felipe Augusto Souza Gualberto, Suely Pires Curti, Maria Isabel de Oliveira, Dewton Moraes-Vasconcelos, Cristina Adelaide Figueiredo Tags: VIROQAS Source Type: research

Escape of pathogens from the host immune response by mutations and mimicry. Possible means to improve vaccine performance
To date, no effective vaccine has been developed against human immunodeficiency virus (HIV 1), Herpes simplex virus (HSV), Hepatitis C virus (HCV) or Plasmodium falciparum. The vaccine strains of influenza A virus have to be changed yearly to protect against the ever evolving virus population. In contrast, vaccines against most other RNA viruses (poliovirus, measles virus, Hepatitis A and B viruses, smallpox virus, etc), which are based on strains used for decades, show no loss of efficacy. A high rate of genetic variation (mutations and recombinations) is generally suggested to account for the escape of certain pathogens ...
Source: Medical Hypotheses - August 24, 2015 Category: Biomedical Science Authors: G. Berger Source Type: research

Aspects on the history of transmission and favor of distribution of viruses by iatrogenic action: perhaps an example of a paradigm of the worldwide spread of HIV
AbstractTransmission of infectious agents might be associated with iatrogenic actions of charitable help in health care. An example is the vaccination against yellow fever in USA that transmitted hepatitis B virus. Another example is injections of praziquantel for treatment and cure of schistosomiasis in Central and Northern Africa, with a focus in Egypt that has spread hepatitis C virus. There is no indication that human T-lymphotropic virus type 1 was spread by injection treatment for African trypanosomiasis, syphilis and treponematosis, but these treatments might have contributed to the early spread of human immunodefic...
Source: Medical Microbiology and Immunology - April 22, 2017 Category: Microbiology Source Type: research