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Infectious Disease: Endemics

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Total 382 results found since Jan 2013.

Bone marrow findings in severe fever with thrombocytopenia syndrome: prominent haemophagocytosis and its implication in haemophagocytic lymphohistiocytosis
Conclusions Haemophagocytosis in the bone marrow of SFTS patients may be common. In SFTS endemic areas, SFTS should be one of the differential diagnoses of fever of unknown origin with haemophagocytosis in the bone marrow.
Source: Journal of Clinical Pathology - May 18, 2016 Category: Pathology Authors: Kim, N., Kim, K.-H., Lee, S. J., Park, S.-H., Kim, I.-S., Lee, E. Y., Yi, J. Tags: Immunology (including allergy) Original article Source Type: research

Rapid Molecular Assays for Specific Detection and Quantitation of Loa Loa Microfilaremia
The risk of fatal reactions in some infected individuals administered drug treatments for Loa loa infection, and the lack of accurate, convenient, diagnostics for this infection have thwarted efforts to eradicate the disease. Time consuming, labor intensive and training intensive microscope-based analysis of blood samples is the standard available diagnostic for Loa loa infection. This new assay technology introduces an easy to use, species-specific, highly sensitive, diagnostic that is able to be performed with minimal training. Positive test results may be indicated by an easily visualized color change and this test may ...
Source: NIH OTT Licensing Opportunities - September 29, 2011 Category: Research Authors: admin Source Type: research

Enteric fever in a British soldier from Sierra Leone
We report the case of a soldier who developed typhoid despite appropriate vaccination and field hygiene measures, which began 23 days after returning from a deployment in Sierra Leone. The incubation period was longer than average, symptoms started 2 days after stopping doxycycline for malaria chemoprophylaxis and initial blood cultures were negative. The Salmonella enterica serovar Typhi eventually isolated was resistant to amoxicillin, co-amoxiclav, co-trimoxazole and nalidixic acid and had reduced susceptibility to ciprofloxacin. He was successfully treated with ceftriaxone followed by azithromycin, but 1 ...
Source: Journal of the Royal Army Medical Corps - May 25, 2016 Category: Journals (General) Authors: Osborne, L. G., Brown, M., Bailey, M. S. Tags: Infectious diseases, Epidemiologic studies, Immunology (including allergy) Case report Source Type: research

Zika Virus Infection: Current Concerns and Perspectives
Abstract The Zika virus outbreaks highlight the growing importance need for a reliable, specific and rapid diagnostic device to detect Zika virus, as it is often recognized as a mild disease without being identified. Many Zika virus infection cases have been misdiagnosed or underreported because of the non-specific clinical presentation. The aim of this review was to provide a critical and comprehensive overview of the published peer‐reviewed evidence related to clinical presentations, various diagnostic methods and modes of transmission of Zika virus infection, as well as potential therapeutic targets to combat...
Source: Clinical Reviews in Allergy and Immunology - May 27, 2016 Category: Allergy & Immunology Source Type: research

Persistent nodal histoplasmosis in nuclear factor kappa B essential modulator deficiency: Report of a case and review of infection in primary immunodeficiencies
Histoplasma capsulatum var. capsulatum is an endemic dimorphic intracellular fungus that typically causes asymptomatic and self-limited infections in immunocompetent individuals.1 Inversely, immunocompromised patients, particularly patients with the acquired immunodeficiency syndrome and other cell-mediated immune defects, are at increased risk for disseminated histoplasmosis.1
Source: Journal of Allergy and Clinical Immunology - April 22, 2016 Category: Allergy & Immunology Authors: Jana P. Lovell, Ladan Foruraghi, Alexandra F. Freeman, Gulbu Uzel, Christa S. Zerbe, Helen Su, Amy P. Hsu, Steven M. Holland Tags: Letter to the Editor Source Type: research

Poorly controlled asthma and strongyloidiasis in a nonendemic area of the United States
Strongyloidiasis is an intestinal infection caused by 2 species of the intestinal nematode Strongyloides, the most common of which is the globally distributed Strongyloides stercoralis.1 S stercoralis occurs in subtropical and tropical countries but is also endemic in several temperate countries where conditions are favorable.2 In the United States, S stercoralis is endemic in the southeastern region.3 The parasite infects humans, other primates, and dogs.2 S stercoralis is mainly transmitted by soil, but interhuman transmission and transmission from infected animals have been reported.
Source: Annals of Allergy, Asthma and Immunology - June 10, 2016 Category: Allergy & Immunology Authors: Santiago Alvarez Arango, Vineet Reddy, David L. Rosenstreich, Sunit P. Jariwala Tags: Letter Source Type: research

Dengue vaccines: Are they safe for travelers?
The four dengue viruses (DENV) circulate among nearly one-half of the world's population in tropical and semitropical countries imposing a huge morbidity burden on travelers. Sanofipasteur has developed a tetravalent live-attenuated vaccine, Dengvaxia, recently approved by the World Health Organization and licensed in four dengue-endemic countries. An additional two dengue vaccines, developed by the National Institute of Allergy and Infectious Diseases (NIAID), USA and Takeda, are entering phase III testing.
Source: Travel Medicine and Infectious Disease - June 21, 2016 Category: Infectious Diseases Authors: Scott B. Halstead, Maira F. Aguiar Tags: Commentary Source Type: research

"It's A Scandal" -Daryl Hall on Doctors Denying Chronic Lyme
Growing up a musically-obsessed child in the 80's, Daryl Hall was one of my biggest inspirations. A masterful, inventive songwriter with an ocean of soul, he set me on the path to being an artist, to never waste a word, and to sing because I mean it. With six number ones and five additional top ten hits throughout the 70's and 80's Daryl Hall and John Oates are the number one duo in music history. Still at the top of his game at 69 years old, Daryl has won legions of new fans with his hit MTV Live show Live From Daryl's House. In February of 2015, at my very sickest from chronic Lyme and Bartonella, after it was missed b...
Source: Science - The Huffington Post - July 22, 2016 Category: Science Source Type: news

Persistent nodal histoplasmosis in nuclear factor kappa B essential modulator deficiency: Report of a case and review of infection in primary immunodeficiencies
Histoplasma capsulatum var. capsulatum is an endemic dimorphic intracellular fungus that typically causes asymptomatic and self-limited infections in immunocompetent individuals.1 Inversely, immunocompromised patients, particularly patients with the acquired immunodeficiency syndrome and other cell-mediated immune defects, are at increased risk for disseminated histoplasmosis.1
Source: Journal of Allergy and Clinical Immunology - April 22, 2016 Category: Allergy & Immunology Authors: Jana P. Lovell, Ladan Foruraghi, Alexandra F. Freeman, Gulbu Uzel, Christa S. Zerbe, Helen Su, Amy P. Hsu, Steven M. Holland Tags: Letter to the Editor Source Type: research

Poorly controlled asthma and strongyloidiasis in a nonendemic area of the United States
Strongyloidiasis is an intestinal infection caused by 2 species of the intestinal nematode Strongyloides, the most common of which is the globally distributed Strongyloides stercoralis.1 S stercoralis occurs in subtropical and tropical countries but is also endemic in several temperate countries where conditions are favorable.2 In the United States, S stercoralis is endemic in the southeastern region.3 The parasite infects humans, other primates, and dogs.2 S stercoralis is mainly transmitted by soil, but interhuman transmission and transmission from infected animals have been reported.
Source: Annals of Allergy, Asthma and Immunology - June 10, 2016 Category: Allergy & Immunology Authors: Santiago Alvarez Arango, Vineet Reddy, David L. Rosenstreich, Sunit P. Jariwala Tags: Letter Source Type: research

Dengue vaccines: Are they safe for travelers?
The four dengue viruses (DENV) circulate among nearly one-half of the world's population in tropical and semitropical countries imposing a huge morbidity burden on travelers. Sanofipasteur has developed a tetravalent live-attenuated vaccine, Dengvaxia, recently approved by the World Health Organization and licensed in four dengue-endemic countries. An additional two dengue vaccines, developed by the National Institute of Allergy and Infectious Diseases (NIAID), USA and Takeda, are entering phase III testing.
Source: Travel Medicine and Infectious Disease - June 21, 2016 Category: Infectious Diseases Authors: Scott B. Halstead, Maira Aguiar Tags: Commentary Source Type: research

Health Official Warns Zika Could Spread Across U.S. Gulf
Aug 21 (Reuters) - One of the top U.S. public health officials on Sunday warned that the mosquito-borne Zika virus could extend its reach across the U.S. Gulf Coast after officials last week confirmed it as active in the popular tourist destination of Miami Beach. The possibility of transmission in Gulf States such as Louisiana and Texas will likely fuel concerns that the virus, which has been shown to cause the severe birth defect known as microcephaly, could spread across the continental United States, even though officials have played down such an outcome. Concern has mounted since confirmation that Zika has expanded in...
Source: Healthy Living - The Huffington Post - August 21, 2016 Category: Consumer Health News Source Type: news

Anthropometric measures are simple and accurate paediatric weight-prediction proxies in resource-poor settings with a high HIV prevalence
Conclusion The development of nomograms using these equations is warranted to allow for rapid and accurate weight prediction from these simple anthropometric measures in HIV-endemic, resource-constrained settings.
Source: Archives of Disease in Childhood - December 13, 2016 Category: Pediatrics Authors: Whitfield, K. C., Wozniak, R., Pradinuk, M., Karakochuk, C. D., Anabwani, G., Daly, Z., MacLeod, S. M., Larson, C. P., Green, T. J. Tags: Immunology (including allergy), HIV/AIDS, Child health, Sexual health Original article Source Type: research

5 Ways The Zika Virus Is Here To Stay
Zika virus’ status as a global health threat may officially be over, but the disease’s impact is far from contained.  The World Health Organization decided in November to end its designation of Zika virus as a public health emergency, but that doesn’t mean that Zika virus has disappeared, explained Dr. Carlos Pardo-Villamizar, a clinical neurologist with an expertise in infectious disorders at Johns Hopkins Medicine. Alongside pressing concerns about how to prevent a resurgence of the disease, health care systems in Brazil and other countries that saw births of babies infected with the disease in ute...
Source: Healthy Living - The Huffington Post - January 4, 2017 Category: Consumer Health News Source Type: news