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Achieving The Quadruple Aim To Deliver Value-Based Allergy Care In An Ever-Evolving Healthcare System.
CONCLUSION: As healthcare systems continue to evolve, allergists and immunologists will play a key role in optimizing value by translating emerging evidence into practice and communicating novel approaches to prevent and treat allergic diseases. PMID: 32289524 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 10, 2020 Category: Allergy & Immunology Authors: Iglesia EGA, Greenhawt M, Shaker MS Tags: Ann Allergy Asthma Immunol Source Type: research

The economics of drug allergy
Purpose of review As drug allergy research aims to inform clinical practice, implementation of best practices may be influenced by financial resources required to incorporate new interventions and the resulting clinical and economic returns on those resource investments. The present review summarizes new insights into the economics of drug allergy over the past year. Recent findings While considering economic implications of recent drug allergy research, many studies have addressed different contextual factors related to the setting, provider, or outcomes. Advances in technology have enabled specialized allergists to ...
Source: Current Opinion in Allergy and Clinical Immunology - June 25, 2020 Category: Allergy & Immunology Tags: SKIN ALLERGY: Edited by Thomas Werfel and Torsten Zuberbier Source Type: research

High anxiety and health-related quality-of-life in families with children with food allergy during COVID-19.
CONCLUSION: Mothers with food allergic children reported high anxiety and poor HRQL. Yet, qualitatively, day-to-day food allergy management was better during the pandemic. PMID: 32950685 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 16, 2020 Category: Allergy & Immunology Authors: Protudjer JLP, Golding M, Salisbury MR, Abrams EM, Roos LE Tags: Ann Allergy Asthma Immunol Source Type: research

Cow's Milk Allergy Prevention.
CONCLUSION: Further research regarding the role early cow's milk ingestion plays in the prevention of cow's milk allergy is required, and questions remain. The absolute amount required for tolerance is unclear. Studies in higher risk populations are required. However, there is an intriguing and increasingly more pervasive association between early ongoing cow's milk ingestion and cow's milk allergy prevention. PMID: 33450397 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 12, 2021 Category: Allergy & Immunology Authors: Abrams EM, Sicherer SH Tags: Ann Allergy Asthma Immunol Source Type: research

Fear of repeated injections in children younger than 4 years receiving subcutaneous allergy immunotherapy.
CONCLUSION: Our analysis suggests that most children receiving weekly subcutaneous immunotherapy lose their fear of injections during the treatment course. Children with increased intervals between visits may be at higher risk of experiencing fear of injections. CLINICAL TRIAL REGISTRATION: clinicaltrial.gov identifier NCT01028560. PMID: 23176889 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - December 1, 2012 Category: Allergy & Immunology Authors: de Vos G, Shankar V, Nazari R, Kooragayalu S, Smith M, Wiznia A, Rosenstreich D Tags: Ann Allergy Asthma Immunol Source Type: research

Anaphylaxis in a tertiary adult allergy clinic: a retrospective review of 516 patients.
CONCLUSION: In this study, the second pattern of National Institute of Allergy and Infectious Disease (NIAID) and the Food Allergy and Anaphylaxis Network (FAAN) diagnostic criteria for anaphylaxis predominated among adult patients. Drugs were the leading triggering factor, followed by Hymenoptera stings, foods, latex, and exercise, respectively. Atopy, asthma, and allergic rhinitis were rarely detected. PMID: 23352528 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - January 30, 2013 Category: Allergy & Immunology Authors: Gelincik A, Demirtürk M, Yılmaz E, Ertek B, Erdogdu D, Colakoğlu B, Büyüköztürk S Tags: Ann Allergy Asthma Immunol Source Type: research

Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data
Conclusions: An infant diet consisting of high levels of fruits, vegetables, and home-prepared foods is associated with less food allergy by the age of 2 years.
Source: Journal of Allergy and Clinical Immunology - July 25, 2013 Category: Allergy & Immunology Authors: Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E.N. Clare Mills, Barrie M. Margetts, Graham Roberts Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin–basophil axis
Conclusion: Epicutaneous sensitization on a disrupted skin barrier is associated with accumulation of TSLP-elicited basophils, which are necessary and sufficient to promote antigen-induced intestinal food allergy.
Source: Journal of Allergy and Clinical Immunology - February 21, 2014 Category: Allergy & Immunology Authors: Mario Noti, Brian S. Kim, Mark C. Siracusa, Gregory D. Rak, Masato Kubo, Amin E. Moghaddam, Quentin A. Sattentau, Michael R. Comeau, Jonathan M. Spergel, David Artis Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Multinational experience with hypersensitivity drug reactions in Latin America.
CONCLUSION: Nonsteroidal anti-inflammatory drugs and antibiotics were the drugs used in at least 75% of patients. More than half the reactions were treated in the emergency department, whereas epinephrine was administered in fewer than 25% of patients with anaphylaxis. Dissemination of guidelines for anaphylaxis among primary and emergency department physicians should be encouraged. PMID: 25065979 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 24, 2014 Category: Allergy & Immunology Authors: Jares EJ, Sánchez-Borges M, Cardona-Villa R, Ensina LF, Arias-Cruz A, Gómez M, Barayazarra S, Bernstein JA, Serrano CD, Cuello MN, Morfin-Maciel BM, De Falco A, Cherrez-Ojeda I, Latin America Drug Allergy Interest Group Tags: Ann Allergy Asthma Immunol Source Type: research

Analysis of a database to predict the result of allergy testing in vivo in patients with chronic nasal symptoms.
CONCLUSION: This study is preliminary to the creation of a software that could help the primary care doctors in a diagnostic decision making process (need of allergy testing) in patients complaining of chronic nasal symptoms. PMID: 25198028 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - September 1, 2014 Category: ENT & OMF Authors: Lacagnina V, Leto-Barone MS, La Piana S, Seidita A, Pingitore G, Di Lorenzo G Tags: Am J Rhinol Allergy Source Type: research

Is food allergy testing reliable in pediatric atopic dermatitis? A population-based study.
Authors: Keck LE, Simpson EL, Berry TM, Hanifin JM Abstract We sought to assess the value and reliability of serologic testing for predicting clinical food allergy in a population-based cohort of infants with atopic dermatitis (AD). Infants 3-18 months of age, recruited from the general population, were followed quarterly for 3 years and carefully evaluated for evidence of immediate reactions to foods. Specific serum IgE levels for six foods were assayed at 3-5 years. Parents were interviewed at each visit regarding past/current immediate food-specific reactions involving skin, gut or respiratory systems. Data were...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Sunlight, vitamin D and food allergy
Purpose of review: The role of vitamin D in the development of food allergy is unclear. We summarize recent data on the epidemiologic link between sunlight (UVB) and food allergy, and evidence for and against a specific role for vitamin D status. Recent findings: Since 2007, most epidemiologic studies have supported low sunlight (as measured by season of birth and latitude) as a risk factor for food allergy. Investigators have also looked directly at vitamin D status (as measured by serum 25OHD level) and its potential role. Although conflicting, the vitamin D studies suggest a more complicated association than a linear do...
Source: Current Opinion in Allergy and Clinical Immunology - June 26, 2015 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Jeffrey G. Demain Source Type: research

Peanut allergy in Mexican children: what is the effect of age at first consumption?
Abstract Studies suggest that children who start solid foods early are at risk for developing food allergies. Herein, we evaluated the effects of the introduction of peanuts to the diets of children on emerging peanut allergies. Children with allergic rhinitis and asthma were enrolled in the present study and evaluated in four stages. In the first stage, a clinical history was completed for all participants. In the second stage, skin tests were conducted to detect the sensitization to peanuts. In the third stage, the parents were interviewed about the peanut-eating habits of their children. In the fourth stage, ch...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 31, 2016 Category: Allergy & Immunology Authors: Bedolla Barajas M, Alcala-Padilla G, Morales Romero J, Camacho Fregoso J, Rivera Mejía V Tags: Iran J Allergy Asthma Immunol Source Type: research

Food allergy quality of life and living with food allergy
Purpose of review: Food allergy quality of life (QoL) has emerged as a key outcome to understand how food-allergic individuals and their families live with disease. Food allergy QoL has been measured since the early 2000's, but in the past 10–12 years, the advent of disease-specific indices has better defined the daily psychological burden of living with disease, which is distinct from measuring quality life in other chronic illnesses where affected patients suffer from more physical symptoms which may cause measurable shifts in disease status. Recent findings: Multiple recent studies from the United States, Europe, and...
Source: Current Opinion in Allergy and Clinical Immunology - April 29, 2016 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Julie Wang Source Type: research

Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge-Our Five Years Experience in Food Allergy Work-up.
Abstract IgE- mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/ or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed  SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral f...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2017 Category: Allergy & Immunology Authors: Zivanovic M, Atanasković-Marković M, Medjo B, Gavrović-Jankulović M, Smiljanić K, Tmušić V, Djurić V Tags: Iran J Allergy Asthma Immunol Source Type: research