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Drug: Lithium
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Medical Comorbidity in Late-Life Bipolar Disorder: A Comparison of Lithium, Valproate, and Other Pharmacotherapies
Introduction: Bipolar disorder is associated with high rates of medical comorbidity, especially in late life. However, little is known about whether certain comorbidities or other medical health outcomes are associated with bipolar pharmacotherapy. Despite on-going concerns regarding lithium safety, we hypothesize that it will not be associated with greater medical comorbidity or acute care use for medical reasons.
Source: The American Journal of Geriatric Psychiatry - March 1, 2016 Category: Geriatrics Authors: Soham Rej, Ching Yu, Kenneth Shulman, Nathan Herrmann, Hadas D. Fischer, Kinwah Fung, Andrea Gruneir Source Type: research
Report: St. Jude sold off older CRM devices after learning of battery issue
St. Jude Medical (NYSE:STJ) continued to distribute outdated pacemaker devices that were indicated in a recall due to battery faults, even after correcting the flaw and producing new units, according to a StarTribune report.
The devices were recalled in 2015 over issues with batteries failing with little to no warning, an issue which resulted in 2 deaths, according to the report. Despite fixing the problem and producing new, updated units, St. Jude continued to distribute the older devices indicated in the recall for 17 months.
Executives at St. Jude reportedly “moved as quickly as possible with the information they...
Source: Mass Device - November 2, 2016 Category: Medical Equipment Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Food & Drug Administration (FDA) Recalls St. Jude Medical Source Type: news
Lithium-related medication problems on nonpsychiatric inpatient medical units.
CONCLUSION: Lithium MRPs were found to have occurred frequently on nonpsychiatric inpatient medical units at 1 hospital. Laboratory test-related MRPs and drug-drug interactions were the most commonly identified types of MRPs. Interventions to address MRPs were not made in the majority of patients; however, interventions were more frequently made when psychiatry consultation was involved.
PMID: 31557277 [PubMed - as supplied by publisher]
Source: American Journal of Health-System Pharmacy : AJHP - September 25, 2019 Category: Drugs & Pharmacology Authors: Alastanos JN, Potter TG, Crouse EL Tags: Am J Health Syst Pharm Source Type: research
Medical treatment of thyrotoxicosis.
Authors: Scappaticcio L, Bellastella G, Maiorino MI, Giovanella L, Esposito K
Abstract
Medical treatment is the primary therapeutic option for thyrotoxicosis/hyperthyroidism. Two groups of causes of thyrotoxicosis (i.e. thyrotoxicosis with hyperthyroidism and thyrotoxicosis without hyperthyroidism) need to be considered for therapeutic reasons. Herein we provide an updated review on the role of conventional medical therapies [i.e. β-blockers, anti-thyroid drugs (ATDs), corticosteroids, inorganic iodide, perchlorate, cholecystographic agents, lithium, cholestyramine] in the main causes of thyrotoxicosis, starting f...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - January 27, 2021 Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Decreasing the Symptoms of Essential Tremor With Medical Painting Therapy
Conclusion The patient reported an increased quality of life (including emotional aspects) and a decrease in her ET, as evidenced by the patient's handwriting. Further research is needed to understand the strengths and limitations of this therapy for ET and related conditions.PMID:35933673 | DOI:10.7812/TPP/20.260
Source: The Permanente journal - August 7, 2022 Category: General Medicine Authors: Monica Elisabeth Winnubst Ricardo Jos é de Almeida Leme Source Type: research
Creativity, Madness and Drugs
Crosby, Stills, Nash & Young in 1970. Credit: Wikimedia Commons/CMA-Creative Management Associates/Atlantic Records San Diego –Would we have Poe’s Raven today if the tormented author had taken lithium to suppress his bipolar illness? Not likely, considering the high frequency of psychiatric illnesses among writers and artists, concluded psychiatrist Kay Jamison of Johns Hopkins Medical School speaking last week at the Society for Neuroscience annual meeting in San Diego. Madness electrifies the creative process, Jamison concluded, but this difficult drug-use dilemma raises an even more provocative question...
Source: Scientific American - Official RSS Feed - November 22, 2013 Category: Science Tags: Mind & Brain Source Type: research
Whole bowel irrigation? Don’t just do something, stand there!
3.5 out of 5 stars
Position paper update: Whole bowel irrigation for gastrointestinal decontamination of overdose patients. Thanacoody R et al. Clin Toxicol 2015 Jan;53:5-12.
Abstract
In 1997 the American Academy of Clinical Toxicology (AACT) and the Euroopean Association of Poisons Centre and Clinical Toxicologists (EAPCCT) published a position paper regarding the use of whole bowel irrigation (WBI) for gastrointestinal decontamination in the poisoned patient. The key conclusions were that no evidence existed showing that WBI improved clinical outcome, and that it should not be used routinely but “may be considered...
Source: The Poison Review - January 13, 2015 Category: Toxicology Authors: Leon Tags: Medical gastrointestinal decontamination overdose poisoning polyethylene glycol position paper whole bowel irrigation Source Type: news
The paroxetine 352 bipolar trial: A study in medical ghostwriting.
CONCLUSIONS: Few industry-sponsored studies gain public scrutiny. It is important to make these articles transparent to the scientific and medical community.
PMID: 23135337 [PubMed - indexed for MEDLINE]
Source: International Journal of Risk and Safety in Medicine - November 30, 2015 Category: Drugs & Pharmacology Tags: Int J Risk Saf Med Source Type: research
Battery-free implantable medical device draws energy directly from human body
Researchers from UCLA and the University of Connecticut have designed a new biofriendly energy storage system called a biological supercapacitor, which operates using charged particles, or ions, from fluids in the human body. The device is harmless to the body ’s biological systems, and it could lead to longer-lasting cardiac pacemakers and other implantable medical devices.The UCLA team was led by Richard Kaner, a distinguished professor of chemistry and biochemistry, and of materials science and engineering, and the Connecticut researchers were led by James Rusling, a professor of chemistry and cell biology. Apaper abo...
Source: UCLA Newsroom: Health Sciences - May 11, 2017 Category: Universities & Medical Training Source Type: news
Abbott upgrades St. Jude Medical cardiac devices
Abbott (NYSE:ABT) said today that it’s upgrading the implantable pacemakers and defibrillators it acquired when it paid $25 billion for St. Jude Medical earlier this year, seeking to move beyond battery and cybersecurity issues that haver plagued it for a year.
Last October St. Jude warned of a battery issue that could disable its high-voltage cardiac rhythm management devices, saying the problem was associated with 2 deaths among the nearly 400,000 patients implanted with affected devices. The issue stemmed from the formation of lithium clusters in the lithium-based batteries used in the devices that can form...
Source: Mass Device - August 29, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Cardiovascular Wall Street Beat Abbott Cardiac Rhythm Management Cybersecurity stjudemedical Source Type: news
Abbott escapes payer ’ s lawsuit over St. Jude Medical CRM batteries
Abbott (NYSE:ABT) this week escaped a purported class action lawsuit brought by a third-party payer over defective batteries used in subsidiary St. Jude Medical‘s cardiac rhythm management devices.
Plaintiff ASEA/AFSCME Local 52 Health Benefits Trust brought the suit last September on behalf of third-party payers, alleging in the U.S. District Court for Northern Illinois that Abbott and St. Jude concealed the battery problems from the public and the FDA.
Little Canada, Minn.-based St. Jude warned about a premature depletion issue with the batteries in October 2016, five years after its battery supplier first repor...
Source: Mass Device - June 21, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Cardiovascular Legal News Abbott stjudemedical Source Type: news
Uremic Encephalopathy Secondary to Medical Noncompliance
BY GREGORY TAYLOR, DO, & CHRISTOPHER COOLEY, DOA 66-year-old woman with a history of type 1 diabetes, hypertension, and end-stage renal disease (ESRD) on hemodialysis presented via EMS to the emergency department with altered mental status. She lived with her family, and they noted that she refused to go to dialysis for her past four sessions and had increasing lethargy for two days.She was afebrile, and her other vital signs were blood pressure 136/92 mmHg, heart rate 77 bpm, respiratory rate 20 bpm, and oxygen saturation 96% on room air. She was agitated and reaching for objects in the sky. Her cardiopulmonary exa...
Source: The Case Files - September 18, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Potential application of medical cotton waste for self-reinforced composite.
Abstract
The present work mainly deals with the efficacy of the waste medical grade cotton (MGC) used for the sustainable self-reinforced composite (SRC). MGC waste was exposed in the autoclave for destroying all microorganisms including infected bacteria's and virus followed by scoured and bleached for removing blood stains and foreign materials. SRC film was prepared by selective dissolved fibre surface of waste MGC into a dissolved microcrystalline cellulose (DMCC) matrix solution prepared by lithium chloride/N,N-dimethylacetamide (LiCl/DMAc) solvent system. The tensile strength of SRC films was significantly i...
Source: International Journal of Biological Macromolecules - November 21, 2018 Category: Biochemistry Authors: Kale RD, Gorade VG Tags: Int J Biol Macromol Source Type: research
Sensors, Vol. 20, Pages 2206: Laser Micromachining of Lithium Niobate-Based Resonant Sensors towards Medical Devices Applications
n Dimov
This paper presents a micromachining process for lithium niobate (LiNbO3) material for the rapid prototyping of a resonant sensor design for medical devices applications. Laser micromachining was used to fabricate samples of lithium niobate material. A qualitative visual check of the surface was performed using scanning electron microscopy. The surface roughness was quantitatively investigated using an optical surface profiler. A surface roughness of 0.526 μm was achieved by laser micromachining. The performance of the laser-micromachined sensor has been examined in different working environments and...
Source: Sensors - April 13, 2020 Category: Biotechnology Authors: Zeyad Yousif Abdoon Al-Shibaany Pavel Penchev John Hedley Stefan Dimov Tags: Article Source Type: research
