The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

The role of BRAF V600E mutation in post-surgical 131I therapy in papillary thyroid carcinoma. A study based on SPECT-CT uptake analysis
Q J Nucl Med Mol Imaging. 2021 Sep 3. doi: 10.23736/S1824-4785.21.03343-4. Online ahead of print.ABSTRACTBACKGROUND: The BRAF V600E mutation (BRAF mut) in papillary thyroid cancer (PTC) has been associated with poor response to therapy with 131I in patients with metastases but the results in postsurgical treatment are controversial. Our main objective is to investigate the impact of the mutation on the biokinetics of the administered 131I therapy after surgery.MATERIALS AND METHODS: A prospective study was designed, from July 2015 to January 2018 which included patients with PTC receiving 131I therapy after surgical treatm...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Maite Dom ínguez-Ayala Pablo M ínguez-Gabiña Miguel Paja-Fano Amaia Bilbao-Gonz ález Amaia Exp ósito-Rodríguez Emilia Rode ño-Ortiz de Zarate Source Type: research

Possibility analysis of thyroid imaging parameters for dose adjustment in 131I treatment of hyperthyroidism
CONCLUSIONS: The corrected thyroid uptake rate is remarkably correlated with clinical characteristic parameters of patients, which can be used to comprehensively evaluate the comprehensive condition of patients with hyperthyroidism.PMID:34477345 | DOI:10.23736/S1824-4785.21.03357-4 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Xiaonan Zhang Junhong Li Hui Zhou Qiteng Lu Hailian Wei Aifeng Li Xinyu Wei Zhixiao Wei Source Type: research

Detection rate of 18F-Choline positron emission tomography/computed tomography in patients with non-metastatic hormone sensitive and castrate resistant prostate cancer
CONCLUSIONS: the rate of positive 18F-Choline PET/CT is similar in patients with a hsPCa and CRPCa, in case of low PSAdt and high GS. Therefore, non-metastatic PCa patients should be assessed by molecular imaging, in order to adapt the most appropriate therapeutic approach.PMID:34477346 | DOI:10.23736/S1824-4785.21.03366-5 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Fabio Zattoni Paolo Artioli Marta Burei Agostino Chiaravalloti Franca Chierichetti Davide Donner Stefano Panareo Ilaria Rambaldi Orazio Schillaci Fabrizio Del Moro Laura Evangelista Source Type: research

[68Ga]DOTA-TATE PET for the detection of early transplant rejection in a heterotopic allograft heart transplantation model of the rat. A pilot study
CONCLUSIONS: We purport that the detected PET signal is primarily a specific marker of lymphocyte infiltration and only to a lesser extent an unspecific marker of infarction and necrosis. Thus, [68Ga]DOTA-TATE PET might be a suitable tool for serial imaging and quantification of lymphocyte infiltration as a direct mediator of acute allograft rejection at an early stage after heart transplantation.PMID:34477347 | DOI:10.23736/S1824-4785.21.03387-2 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - September 3, 2021 Category: Nuclear Medicine Authors: Sebastian Lehner Andrei Todica Guido B öning Stefan Buchholz Peter Bartenstein Marcus Hacker Harun Ilhan Source Type: research

Reduction of emission time for [68Ga]Ga-PSMA PET/CT using the digital biograph vision: a Phantom study
CONCLUSIONS: A reduction of single-bed and whole-body scan time for [68Ga]Ga-PSMA PET/CT compared to current clinically recommended acquisition protocols is postulated Clinical studies are warranted to validate the applicability of this protocol.PMID:34309334 | DOI:10.23736/S1824-4785.21.03300-8 (Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging)
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - July 26, 2021 Category: Nuclear Medicine Authors: Pedro Fragoso Costa Walter Jentzen Finja S ÜßELBECK Wolfgang P Fendler Christoph Rischpler Ken Herrmann Maurizio Conti David Kersting Manuel Weber Source Type: research