Mono- and poly-therapy with benzodiazepines or Z-drugs: Results from a tertiary-care Addiction Unit study
Int J Risk Saf Med. 2021 Jun 10. doi: 10.3233/JRS-210014. Online ahead of print.ABSTRACTBACKGROUND: Using benzodiazepines (BZDs) or Z-drugs in poly-therapy is a critical issue.OBJECTIVE: Identifying factors influencing the use of BZDs/Z-drugs in poly- vs mono-therapy in patients with or without substance use disorders (SUDs).METHODS: 986 inpatients were analysed. Socio-demographic and clinical variables were collected. BZD/Z-drug doses were compared via the Defined Daily Dose (DDD) and standardized as diazepam dose equivalents. Mann-Whitney, Chi-square, Fisher test, hierarchical multivariate regression analyses were run re...
Source: International Journal of Risk and Safety in Medicine - June 14, 2021 Category: Drugs & Pharmacology Authors: Giovanni Mansueto Fabio Lugoboni Rebecca Casari Anna Bertoldi Fiammetta Cosci Source Type: research

Companies' statements about drugs withdrawn from the Canadian market: A descriptive analysis
CONCLUSION: In 15 out of 22 cases, the company either disagreed with the decision to withdraw the drug or felt that the drug should continue to be available to Canadian patients.PMID:34057099 | DOI:10.3233/JRS-210013 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - May 31, 2021 Category: Drugs & Pharmacology Authors: Joel Lexchin Source Type: research

Pheniramine dependence in obsessive-compulsive disorder: A case report
We report a case of pheniramine dependence in a patient with obsessive-compulsive disorder. The patient took about 250 mg orally daily and injected about 90 mg every week from the last six months. It reduced his anxiety, was cheaper than his other psychiatric medications, and free of stigma. He had lethargy, headache, uneasiness, anxiety, and poor sleep as withdrawal symptoms.RESULTS: This case highlights the vulnerability of those with psychiatric disorders towards pheniramine abuse. Hence, this report advocates the strict evaluation of over-the-counter drugs for patients with pre-existing psychiatric disorders.PMID:33967...
Source: International Journal of Risk and Safety in Medicine - May 10, 2021 Category: Drugs & Pharmacology Authors: Dron Kinnarbhai Bhandutia Swarna Buddha Nayok Dhanashree Akshatha H S Sathyanarayana Malleshwara Thimmaiah Source Type: research

What is 'risk and safety in medicine'?
Int J Risk Saf Med. 2021;32(2):75-76. doi: 10.3233/JRS-211001.NO ABSTRACTPMID:33935109 | DOI:10.3233/JRS-211001 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - May 3, 2021 Category: Drugs & Pharmacology Authors: I Ralph Edwards Marie Lindquist Source Type: research

What is 'risk and safety in medicine'?
Int J Risk Saf Med. 2021 Apr 23. doi: 10.3233/JRS-211001. Online ahead of print.NO ABSTRACTPMID:33935109 | DOI:10.3233/JRS-211001 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - May 3, 2021 Category: Drugs & Pharmacology Authors: I Ralph Edwards Marie Lindquist Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research

Occupational health risk assessment at healthcare institutions: Developing a semi-quantitative risk method
CONCLUSION: To overcome the shortcomings of the proposed health risk assessment methods, a semi-quantitative method was used in the present study to more accurately calculate the risk levels in the healthcare institutions and also calculate the risk level of each hospital unit. The proposed semi-quantitative method can be used as a tool for assessing occupational health risks as a key element of risk management. In addition, by focusing on an appropriate framework for occupational health risk assessment, specialists in the organization will be able to take significant and effective steps to implement an efficient risk mana...
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Mohammad Hossein Chalak Ghasem Bahramiazar Javad Rasaee Reza Fahimi Asghar Noran Anbardan Hossein Jafari Fatemeh Ramroudi Nasab Source Type: research

Off-label drug use and the risk of medication errors in critically ill neonates: A conceptual pilot study
CONCLUSION: Significant proportions of critically ill neonates received at least one OLD/unlicensed drug and such use was associated with potentially increased risk of medication errors.PMID:33646182 | DOI:10.3233/JRS-200058 (Source: International Journal of Risk and Safety in Medicine)
Source: International Journal of Risk and Safety in Medicine - March 1, 2021 Category: Drugs & Pharmacology Authors: Kannan Sridharan Muna Al Jufairi Eman Al Ansari Source Type: research