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Drug: Ciprofloxacin

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Total 6685 results found since Jan 2013.

Observation of a new pattern of mutations in gyrA and parC within Escherichia coli exhibiting fluroquinolone resistance
Nivedita Dasgupta, Deepjyoti Paul, Debadatta Dhar Chanda, Shiela Chetri, Atanu Chakravarty, Amitabha BhattacharjeeIndian Journal of Medical Microbiology 2018 36(1):131-135Therapeutic options with quinolones are severely compromised in infections caused by members of Enterobacteriaceae family. Mutations in chromosomal region are one of the major reasons for bacterial resistance towards this group of antibiotic. The aim of the study is to detect the mutations in gyr A and par C responsible for quinolone resistance among clinical isolates of Escherichia coli. A total of 96 quinolone-resistant clinical isolates of E. coli were...
Source: Indian Journal of Medical Microbiology - May 2, 2018 Category: Microbiology Authors: Nivedita Dasgupta Deepjyoti Paul Debadatta Dhar Chanda Shiela Chetri Atanu Chakravarty Amitabha Bhattacharjee Source Type: research

Rise in Possible Fluoroquinolone-Resistant Shigella Isolates Rise in Possible Fluoroquinolone-Resistant Shigella Isolates
The CDC is seeing an increasing number of Shigella isolates that test within the susceptible range for the fluoroquinolone antibiotic ciprofloxacin but harbor one or more resistance mechanisms.Medscape Medical News
Source: Medscape Medical News Headlines - June 7, 2018 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Alarming resistance of Neisseria gonorrhoeae in a tertiary care hospital of North India
Conclusion: Alarming increase in the resistance to commonly used antimicrobials for gonorrhoea in our study, especially of fluoroquinolones, is a clarion call for the urgent need for prudence in prescribing them. Observing the rampant resistance exhibited by N. gonorrhoeae, it is clear that the day is not far when it will acquire a superbug status and become intractable to treatment by the available antibiotics.
Source: Indian Journal of Medical Microbiology - August 7, 2018 Category: Microbiology Authors: Mohit Sharma Meher Rizvi Richa Gupta Mohd Azam Haris M Khan Anjum Parvez Indu Shukla Source Type: research

Medical News Today: Treating urinary tract infections with Cipro
Cipro is an antibiotic that doctors use to treat urinary tract infections (UTIs). For Cipro to work, people must take the full course of the drug and follow their doctor's instructions. But some people may be at risk of severe side effects if they take Cipro, and they may need to consider alternatives. Learn more here.
Source: Health News from Medical News Today - September 7, 2018 Category: Consumer Health News Tags: Urinary Tract Infection Source Type: news

Trends in antibiotic susceptibility of enteric fever isolates from South India, 2002–2013
ConclusionsKnowledge of the local patterns of resistance would help in appropriate therapy for enteric fever. With increasing rates of fluoroquinolone resistance in our hospital setting, it is probably prudent to revert back to the first-line agents for treatment and save azithromycin and third-generation cephalosporins for difficult and non-responsive cases.
Source: Medical Journal Armed Forces India - October 26, 2018 Category: General Medicine Source Type: research

Prevalence and Antimicrobial Susceptibility of Bacterial Uropathogens Isolated from Pediatric Patients at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia.
Conclusion: This study determined the prevalence of urinary tract infection in pediatric patients and highlighted the major bacterial uropathogens involved in UTI for the first time in the country. Furthermore, bacterial pathogen species and their frequency was consistent with the usually reported pattern, with E. coli being the most common organism isolated in cases of urinary tract infections followed by Klebsiella spp. Most of the bacterial isolates were multidrug resistant, and it is therefore suggested that appropriate antimicrobials should be administered to reduce the risk of multidrug resistant organisms developing...
Source: International Journal of Microbiology - November 4, 2018 Category: Microbiology Tags: Int J Microbiol Source Type: research

In vitro activity of mecillinam and nitroxoline against Neisseria gonorrhoeae - re-purposing old antibiotics in the multi-drug resistance era.
Abstract In 2018, the European Centre for Disease Prevention and Control reported the first cases of extensively drug-resistant Neisseria gonorrhoeae infections in Europe. Seeking new options for antimicrobial therapy we investigated the susceptibility of N. gonorrhoeae to nitroxoline (NIT) and mecillinam (MCM), both of which are currently only indicated to treat uncomplicated urinary tract infections. Clinical N. gonorrhoeae isolates with non-susceptibility to penicillin from two German medical centres were included (n =27). Most isolates were also non-susceptible to a range of other anti-gonococcal antimicrobial...
Source: Journal of Medical Microbiology - June 3, 2019 Category: Microbiology Authors: Fuchs F, Wille J, Hamprecht A, Parcina M, Lehmann C, Schwarze-Zander C, Seifert H, Higgins PG Tags: J Med Microbiol Source Type: research

Prevention And Medical Treatment Of Pouchitis In Ulcerative Colitis.
Abstract Approximately 50% of patients who have undergone IPAA surgery for Ulcerative Colitis (UC) develop at least 1 episode of pouchitis. Patients with pouchitis have a wide range of symptoms, endoscopic and histologic features, disease course, and prognosis. To date, there are no universally accepted diagnostic criteria in terms of endoscopy and histology; though, semi-objective assessments to diagnose pouchitis in patients with ileal pouch- anal anastomosis (IPAA) have been proposed using composite scores such as the Pouchitis Triad, Heidelberg Pouchitis Activity Score and Pouchitis Disease Activity Index (PDA...
Source: Current Drug Targets - July 22, 2019 Category: Drugs & Pharmacology Authors: Benlice C, Shen B, Steele SR Tags: Curr Drug Targets Source Type: research

Non-tuberculous mycobacteria profiles and their anti-mycobacterial resistance at a major medical center in Lebanon
Conclusion: The revelaed different NTM species, with predominance ofM.simiaeand various AMR profiles provide a current epidemiologic database and help guiding the selection of appropriate empirical therapy once the clinical relevance is established.
Source: The Journal of Infection in Developing Countries - July 31, 2019 Category: Infectious Diseases Source Type: research

Rhabdomyolysis Associations with Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS).
Conclusions: This study confirms prior evidence for rhabdomyolysis associations with daptomycin, macrolides, trimethoprim-sulfamethoxazole, linezolid, fluoroquinolones, and cefdinir. This study also identifies previously unknown rhabdomyolysis associations with meropenem, cefditoren, cefaclor, and piperacillin-tazobactam. PMID: 31673242 [PubMed - in process]
Source: International Journal of Medical Sciences - November 2, 2019 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Review of a 7-year record of the bacteriological profile of airway secretions of children with cystic fibrosis in North India
Conclusions: The pattern of airway colonisation in the Indian setting is different from the Caucasian population, and P. aeruginosa and Burkholderia cepacia complex appear early. Colonisation with P. aeruginosa benefits from therapy. In case of infection, care must be taken while initiating empiric therapy. It should be based on local antibiograms to prevent the emergence of resistant microbes.
Source: Indian Journal of Medical Microbiology - November 18, 2019 Category: Microbiology Authors: Vikas Gautam Parinitha Kaza Joseph L Mathew Varpreet Kaur Megha Sharma Pallab Ray Source Type: research

Molecular surveillance of carbapenemase-producing Pseudomonas aeruginosa at three medical centres in Cologne, Germany
ConclusionsThese data give insight into the epidemiology of CPPA in three centres in Germany over a period of 3 years. Carbapenemases are a relevant resistance mechanism in 4MRGN-P. aeruginosa, illustrated by genetically related VIM-2-producing strains that seem to be endemic in this region. Our data suggest that infection control measures should especially focus on controlling transmission on the ICU and support the need for a local molecular surveillance system.
Source: Antimicrobial Resistance and Infection Control - December 29, 2019 Category: Infectious Diseases Source Type: research

Ciprofloxacin-resistant Gram-negative isolates from a tertiary care hospital in Eastern India with novel gyrA and parC gene mutations
ConclusionCiprofloxacin resistance observed in our study was mostly due to point mutations. Hence, strategies for rational use of ciprofloxacin and adherence to the dose and duration of treatment could be helpful to prevent selection and spread of mutant CRIs/strains.
Source: Medical Journal Armed Forces India - January 9, 2020 Category: General Medicine Source Type: research

G-CSF Cuts Febrile Neutropenia Rates in Early Breast Cancer G-CSF Cuts Febrile Neutropenia Rates in Early Breast Cancer
Women with early-stage breast cancer had a lower rate of febrile neutropenia when given G-CSF alongside their chemotherapy rather than ciprofloxacin.Medscape Medical News
Source: Medscape Medical News Headlines - June 9, 2020 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Investigation of antimicrobial resistance and virulence genes of Campylobacter isolates from patients in a tertiary hospital in Edirne, Turkey
Conclusions: It was detected that there is an increase in antimicrobial resistance of Campylobacter strains in our region, and most of the isolates harbour virulence genes.
Source: Indian Journal of Medical Microbiology - August 28, 2020 Category: Microbiology Authors: Canan Eryildiz Kiymet Tabakcioglu Gulcan Kuyucuklu Nermin Sakru Source Type: research