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Drug: Methotrexate

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Total 6619 results found since Jan 2013.

Management of Cesarean Scar Pregnancy: A Case Series
Conclusions The accurate diagnosis of CSP is important. Curettage after UAE with or without local MTX infusion is a safe and effective method.
Source: Chinese Medical Sciences Journal - January 12, 2016 Category: Journals (General) Source Type: research

Changes of glycosylation of IgG in rheumatoid arthritis patients treated with methotrexate
Conclusions Defect of galactosylation of IgG in RA patients is a useful marker of disease activity that may be used for the assessment of therapy effectiveness. The role of IgG fucosylation and sialylation in RA pathogenesis has still to be determined.
Source: Advances in Medical Sciences - January 14, 2016 Category: Biomedical Science Source Type: research

Medical management of cesarean scar pregnancy at advanced age: case report and literature review.
CONCLUSION: Cesarean scar pregnancy is a rare type of ectopic pregnancy that is increasing in number due to the increase in cesarean deliveries. Clinical vigilance is imperative for diagnosis and treatment of this highly mortal and morbid entity. PMID: 27048038 [PubMed - in process]
Source: Clinical and Experimental Obstetrics and Gynecology - April 8, 2016 Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research

Tocilizumab efficacy in a patient with positive anti-CCP chronic Lyme arthritis
Conclusion: Off label treatment by biologic disease modifying antirheumatic drugs can be considered in selected patients with severe antibiotic-resistant Lyme arthritis.C.
Source: North American Journal of Medical Sciences - April 7, 2016 Category: Journals (General) Authors: Julianna HirschItzhak RosnerDoron RimarLisa KalyMichael RozenbaumNina BoulmanGleb Slobodin Source Type: research

Medical Management of Ectopic Pregnancy with Single-Dose and Two-Dose Methotrexate Protocols: Human Chorionic Gonadotropin Trends and Patient Outcomes
Ectopic pregnancy, though rare, is an important cause of female morbidity and mortality and early, effective treatment is critical. Systemic methotrexate has become widely accepted as a safe and effective alternative to surgery in the stable patient. As the number and timing of methotrexate doses differ in the three main medical treatment regimens, one might expect trends in serum human Chorionic Gonadotropin and time to resolution to vary depending on protocol. Furthermore, human Chorionic Gonadotropin trends and time to resolution may predict ultimate treatment success.
Source: American Journal of Obstetrics and Gynecology - June 27, 2016 Category: OBGYN Authors: Michelle C. Mergenthal, Suneeta Senapati, Jarcy Zee, Lynne Allen-Taylor, Paul G. Whittaker, Peter Takacs, Mary D. Sammel, Kurt T. Barnhart Source Type: research

Medical management of ectopic pregnancy with single-dose and 2-dose methotrexate protocols: human chorionic gonadotropin trends and patient outcomes
Ectopic pregnancy, although rare, is an important cause of female morbidity and mortality and early, effective treatment is critical. Systemic methotrexate has become widely accepted as a safe and effective alternative to surgery in the stable patient. As the number and timing of methotrexate doses differ in the 3 main medical treatment regimens, one might expect trends in serum human chorionic gonadotropin and time to resolution to vary depending on protocol. Furthermore, human chorionic gonadotropin trends and time to resolution may predict ultimate treatment success.
Source: American Journal of Obstetrics and Gynecology - June 27, 2016 Category: OBGYN Authors: Michelle C. Mergenthal, Suneeta Senapati, Jarcy Zee, Lynne Allen-Taylor, Paul G. Whittaker, Peter Takacs, Mary D. Sammel, Kurt T. Barnhart Tags: Original Research Source Type: research

Intravitreal injections of methotrexate in treatment of primary central nervous system lymphoma with intraocular involvement
Publication date: Available online 22 August 2016 Source:The Kaohsiung Journal of Medical Sciences Author(s): Ya-Chi Huang, Jieh-Ren Jou
Source: The Kaohsiung Journal of Medical Sciences - August 22, 2016 Category: Universities & Medical Training Source Type: research

Subcutaneous Methotrexate Safe, Effective for Psoriasis Subcutaneous Methotrexate Safe, Effective for Psoriasis
Subcutaneous methotrexate with an intensified 52-week dosing schedule should be considered for patients with psoriasis because of its favorable risk-benefit profile.Medscape Medical News
Source: Medscape Medical News Headlines - December 30, 2016 Category: Consumer Health News Tags: Dermatology News Source Type: news

Medication errors associated with oral administration of methotrexate. Data from spontaneous reporting and medical literature review.
Authors: Salgueiro-Vázquez ME, Sáinz Gil M, Fernández Peña S, Martín Arias LH PMID: 28139214 [PubMed - as supplied by publisher]
Source: Medicina Clinica - February 1, 2017 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

Baricitinib Might Offer Oral Alternative to Adalimumab in RA Baricitinib Might Offer Oral Alternative to Adalimumab in RA
A phase 3 trial in patients with rheumatoid arthritis who did not respond to methotrexate showed that the addition of baricitinib produced significant clinical improvements.Medscape Medical News
Source: Medscape Medical News Headlines - February 22, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Successful medical treatment of a hepatic pregnancy: a case report
ConclusionsThe interest of this case resides in the rarity of this condition and the therapeutic approach used. Clinicians should raise their index of suspicion for hepatic pregnancy when faced with females of reproductive age with such a clinical presentation.
Source: Journal of Medical Case Reports - March 14, 2017 Category: Journals (General) Source Type: research

Management of a Viable Cesarean Scar Pregnancy: A Case Report.
Authors: Roy MM, Radfar F Abstract The incidence of cesarean scar pregnancy (CSP), which was extremely rare till recent times, has been rising steadily. We have more of such cases being published in medical literature now. A 38-year-old woman with a past history of previous three cesarean sections presented with five weeks pregnancy and complaints of bleeding per vaginum associated with mild lower abdominal discomfort. The diagnosis of CSP with a live fetus within the gestational sac was made on a transvaginal ultrasound examination and later confirmed with a magnetic resonance imaging (MRI). The management involve...
Source: Oman Medical Journal - April 26, 2017 Category: Middle East Health Tags: Oman Med J Source Type: research

Triple Therapy More Cost-Effective Than MTX + Biologic in RA Triple Therapy More Cost-Effective Than MTX + Biologic in RA
Switching patients with MTX-resistant RA to triple-drug therapy (methotrexate, hydroxychloroquine, sulfasalazine) was recommended before changing to more expensive biologic therapy.Medscape Medical News
Source: Medscape Medical News Headlines - May 30, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Tocilizumab Triumphs in Methotrexate Combo for RA Tocilizumab Triumphs in Methotrexate Combo for RA
It is not always clear which biologic to add to methotrexate for rheumatoid arthritis, but a new comparison between tocilizumab and a number of TNF inhibitors has some suggestions.Medscape Medical News
Source: Medscape Medical News Headlines - June 20, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news