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Eleven science stories likely to make big news in 2023
As the COVID-19 pandemic enters its fourth year as a global health emergency, researchers will continue pushing to help make the disease manageable and ordinary. They will track hundreds of subvariants of Omicron, the highly transmissible but seemingly less lethal strain of SARSCoV-2 that dominated in 2022. Virologists will watch the virus’ evolution this year to see whether it has finally slowed or a more dangerous variant pops up, evading much of the immunity that humanity has built up to previous ones. Vaccine researchers hope to develop new shots that provide broad protection against a variety of coronaviruses.  Ano...
Source: ScienceNOW - January 4, 2023 Category: Science Source Type: news

News at a glance: Earth ’s top geological sites, cameras on sharks, and China’s space station
NATURAL HISTORY Science society lists Earth’s top ‘geoheritage’ sites The International Union of Geological Sciences last week marked its 60th anniversary by announcing a list of 100 “geoheritage” sites that have substantially influenced understanding of Earth’s deep history . The global list, released in collaboration with UNESCO, is meant to foster conservation and tourism. The sites include familiar ones, such as the Grand Canyon’s “great unconformity,” a billion-year gap in the rock record erased by erosion. More exotic examples include limestones in Germany that preserve Arc...
Source: Science of Aging Knowledge Environment - November 3, 2022 Category: Geriatrics Source Type: research

News at a glance: New gene therapy, Europe ’s drought, and a black hole’s photon ring
ARCHAEOLOGY Drought exposes ‘Spanish Stonehenge’ for study Scientists are rushing to examine a 7000-year-old stone circle in central Spain that had been drowned by a reservoir for decades and was uncovered after the drought plaguing Europe lowered water levels. Nicknamed the “Spanish Stonehenge”—although 2000 years older than the U.K. stone circle—the Dolmen of Guadalperal (above) was described by archaeologists in the 1920s. The approximately 100 standing stones, up to 1.8 meters tall and arranged around an oval open space, were submerged in the Valdecañas reservoir after the construction of a ...
Source: Science of Aging Knowledge Environment - August 25, 2022 Category: Geriatrics Source Type: research

Biphasic anaphylaxis after first dose of messenger RNA coronavirus disease 2019 vaccine with positive polysorbate 80 skin testing result
We present the case of an individual who experienced suspected biphasic anaphylaxis after the first dose of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine.
Source: Annals of Allergy, Asthma and Immunology - August 2, 2021 Category: Allergy & Immunology Authors: Mitchell M. Pitlick, Miguel A. Park, Alexei Gonzalez-Estrada, Sergio E. Chiarella Tags: Letters Source Type: research

Face masks suitable for preventing COVID-19 and pollen allergy. A  study in the exposure chamber
ConclusionWearing a  mask during pollen season can be recommended as an effective nondrug option for people with a pollen allergy.
Source: Allergo Journal International - July 14, 2021 Category: Allergy & Immunology Source Type: research

What We Learned About Genetic Sequencing During COVID-19 Could Revolutionize Public Health
You don’t want to be a virus in Dr. David Ho’s lab. Pretty much every day since the COVID-19 pandemic began, Ho and his team have done nothing but find ways to stress SARS-CoV-2, the virus that causes the disease. His goal: pressure the virus relentlessly enough that it mutates to survive, so drug developers can understand how the virus might respond to new treatments. As a virologist with decades of experience learning about another obstinate virus, HIV, Ho knows just how to apply that mutation-generating stress, whether by starving the virus, bathing it in antibodies that disrupt its ability to infect cells, ...
Source: TIME: Health - June 11, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 feature Genetics Magazine Source Type: news

Risk of allergic reaction in patients with atopic disease and recent coronavirus disease 2019 vaccination
The number of cases of coronavirus disease 2019 (COVID-19) has exceeded 20 million in the United States as of January 3, 2021.1 On December 11, 2020, an Emergency Use Authorization was issued by the Food and Drug Administration for the use of the Pfizer-BioNTech (Pfizer, Inc., New York, NY; and BioNTech SE, Germany) vaccine for the prevention of COVID-19.1 The Moderna (Moderna, Inc., Cambridge, MA) COVID-19 vaccine became available by Emergency Use Authorization 1 week after, on December 18, 2021.
Source: Annals of Allergy, Asthma and Immunology - May 4, 2021 Category: Allergy & Immunology Authors: Kelley N. Dages, Mitchell M. Pitlick, Avni Y. Joshi, Miguel A. Park Tags: Letters Source Type: research

Polyethylene glycol and polysorbate skin testing in the evaluation of coronavirus disease 2019 vaccine reactions
In December 2020, the US Food and Drug Administration (FDA) issued emergency use authorizations for coronavirus disease 2019 (COVID-19) vaccines from Pfizer-BioNTech and Moderna, and widespread vaccination is ongoing. Contraindications to vaccination include a history of immediate allergic reaction to a component or previous dose of an messenger RNA (mRNA) COVID-19 vaccine.1 As of January 18, 2021, anaphylaxis to the Pfizer-BioNTech (Pfizer Inc, New York, New York, BioNTech SE, Mainz, Germany) and Moderna (Moderna, Inc, Cambridge, Massachusetts) vaccines have occurred at rates of 4.7 and 2.5 cases per million doses, respectively.
Source: Annals of Allergy, Asthma and Immunology - March 25, 2021 Category: Allergy & Immunology Authors: Mitchell M. Pitlick, Andrea N. Sitek, Susan A. Kinate, Avni Y. Joshi, Miguel A. Park Tags: Letters Source Type: research

mRNA Technology Gave Us the First COVID-19 Vaccines. It Could Also Upend the Drug Industry
“No!” The doctor snapped. “Look at me!” I had been staring her in the eyes, as she had ordered, but when a doctor on my other side began jabbing me with a needle, I started to turn my head. “Don’t look at it,” the first doctor said. I obeyed. This was in early August in New Orleans, where I had signed up to be a participant in the clinical trial for the Pfizer-BioNTech COVID-19 vaccine. It was a blind study, which meant I was not supposed to know whether I had gotten the placebo or the real vaccine. I asked the doctor if I would really been able to tell by looking at the syringe. &...
Source: TIME: Health - January 11, 2021 Category: Consumer Health News Authors: Walter Isaacson Tags: Uncategorized COVID-19 feature Magazine Source Type: news

The Great Vaccine Race: Inside the Unprecedented Scramble to Immunize the World Against COVID-19
The cleverest of enemies thrive on surprise attacks. Viruses—and coronaviruses in particular—know this well. Remaining hidden in animal hosts for decades, they mutate steadily, sometimes serendipitously morphing into more effective and efficient infectious agents. When a strain with just the right combination of genetic codes that spell trouble for people makes the leap from animal to human, the ambush begins. Such was the case with SARS-CoV-2, the coronavirus behind COVID-19, and the attack was mostly silent and insidious at first. Many people infected with SARS-CoV-2 remained oblivious as they served as the v...
Source: TIME: Health - September 10, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Magazine Source Type: news

Why the U.S. Is Losing the War On COVID-19
It is a frightening time to live in the United States. COVID-19, a novel disease as ruthless as it is seemingly random, is picking us off by the thousands; even many of those who “recover” may never truly be the same again. The pandemic has exposed the gulf between what this country promises for its citizens and what it actually delivers. And as the U.S. barrels toward Election Day, the outbreak is sure to complicate the voting process, with potentially disastrous results. For a short time in the spring, it appeared the U.S. was getting a grip on its outbreak. Hard-hit states like New York successfully flattene...
Source: TIME: Science - August 13, 2020 Category: Science Authors: Alex Fitzpatrick Tags: Uncategorized COVID-19 UnitedWeRise20Disaster Source Type: news

Use of Google Trends to investigate loss ‐of‐smell‒related searches during the COVID‐19 outbreak
ConclusionThere is a strong correlation between the frequency of searches for smell ‐related information and the onset of COVID‐19 infection in Italy, Spain, UK, USA, Germany, France, Iran, and The Netherlands. We hypothesize this may relate to a previously underrecognized symptom.
Source: International Forum of Allergy and Rhinology - June 14, 2020 Category: Allergy & Immunology Authors: Abigail Walker, Claire Hopkins, Pavol Surda Tags: ORIGINAL ARTICLE Source Type: research

SARS-CoV-2 antibody testing —questions to be asked
Severe acute respiratory syndrome coronavirus 2 infection and development of coronavirus disease 2019 presents a major health care challenge of global dimensions. Laboratory diagnostics of infected patients, and the assessment of immunity against severe acute respiratory syndrome coronavirus 2, presents a major cornerstone in handling the pandemic. Currently, there is an increase in demand for antibody testing and a large number of tests are already marketed or are in the late stage of development.
Source: Journal of Allergy and Clinical Immunology - May 27, 2020 Category: Allergy & Immunology Authors: Mustafa K. Özçürümez, Andreas Ambrosch, Oliver Frey, Verena Haselmann, Stefan Holdenrieder, Michael Kiehntopf, Michael Neumaier, Michael Walter, Folker Wenzel, Roman Wölfel, Harald Renz, COVID-19 Task Force of the German Society for Clinical Chemistr Tags: Reviews and feature articles Source Type: research

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