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Total 703 results found since Jan 2013.

Hypertension in pregnancy and risk of coronary heart disease and stroke: a prospective study in a large UK cohort
We examined the prospective relation between a history of hypertension during pregnancy and coronary heart disease (CHD) and stroke in middle-aged UK women.Methods: In 1996 –2001, 1.1 million parous women (mean age=56years) without vascular disease at baseline reported their history of hypertension during pregnancy and other factors.
Source: International Journal of Cardiology - July 31, 2016 Category: Cardiology Authors: Dexter Canoy, Benjamin J. Cairns, Angela Balkwill, F. Lucy Wright, Asma Khalil, Valerie Beral, Jane Green, Gillian Reeves, Million Women Study Collaborators Source Type: research

20 Defective placental bed vascular remodeling precedes manifestations of superimposed preeclampsia in stroke-prone spontaneously hypertensive rats
Conclusion Our data confirms the characterization of pregnant SHRSP as a model reproducing clinical diagnostic traits and the underlying placental pathology observed in preeclampsia superimposed on chronic hypertension. This novel model provides an attractive system for interventional studies and dissection of the multifactorial origins of hypertensive disorders of pregnancy.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 3, 2016 Category: OBGYN Source Type: research

Role of Tumor Necrosis Factor-{alpha} and Natural Killer Cells in Uterine Artery Function and Pregnancy Outcome in the Stroke-Prone Spontaneously Hypertensive RatNovelty and Significance Pregnancy and Hypertension
Women with chronic hypertension are at increased risk of maternal and fetal morbidity and mortality. We have previously characterized the stroke-prone spontaneously hypertensive rat (SHRSP) as a model of deficient uterine artery function and adverse pregnancy outcome compared with the control Wistar–Kyoto. The activation of the immune system plays a role in hypertension and adverse pregnancy outcome. Therefore, we investigated the role of tumor necrosis factor-α in the SHRSP phenotype in an intervention study using etanercept (0.8 mg/kg SC) at gestational days 0, 6, 12, and 18 in pregnant SHRSP compared with vehicle-tre...
Source: Hypertension - October 11, 2016 Category: Cardiology Authors: Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T. J., Graham, D., Delles, C. Tags: Animal Models of Human Disease, Basic Science Research, Inflammation, Hypertension, Preeclampsia Original Articles Source Type: research

Risk of Pregnancy-Associated Stroke Across Age Groups
This population-based cohort study uses data from the New York State SPARCS database to examine the risk of stroke in women of childbearing age who are pregnant or post partum compared with the risk in those who are not pregnant.
Source: JAMA Neurology - October 24, 2016 Category: Neurology Source Type: research

Stroke Risk Can Rise With Pregnancy-Linked High Blood Pressure
THURSDAY, May 25, 2017 -- Several factors raise the risk of pregnancy-related stroke in women with preeclampsia, a new study suggests. Preeclampsia is a condition marked by high blood pressure and protein in a pregnant woman ' s urine. It affects...
Source: Drugs.com - Daily MedNews - May 25, 2017 Category: General Medicine Source Type: news

Stroke Risk Can Rise with Pregnancy-Linked High Blood Pressure
Infections, clotting disorders, history of high blood pressure puts women with preeclampsia in jeopardy, study says Source: HealthDay Related MedlinePlus Pages: High Blood Pressure in Pregnancy, Stroke
Source: MedlinePlus Health News - May 25, 2017 Category: Consumer Health News Source Type: news

Study uncovers stroke risk factors in preeclampsia
A new study by Columbia University Medical Center has identified certain conditions that increase stroke risk for pregnant women with preeclampsia.
Source: Health News - UPI.com - May 26, 2017 Category: Consumer Health News Source Type: news

Defective trophoblast invasion underlies fetal growth restriction and preeclampsia-like symptoms in the stroke-prone spontaneously hypertensive rat
AbstractSTUDY QUESTIONWhat is the impact of chronic hypertension on placental development, fetal growth and maternal outcome in the stroke-prone spontaneously hypertensive rat (SHRSP)?SUMMARY ANSWERSHRSP showed an impaired remodeling of the spiral arteries and abnormal pattern of trophoblast invasion during placentation, which were associated with subsequent maternal glomerular injury and increased baseline hypertension as well as placental insufficiency and asymmetric fetal growth restriction (FGR).WHAT IS KNOWN ALREADYA hallmark in the pathogenesis of preeclampsia (PE) is abnormal placentation with defective remodeling o...
Source: Molecular Human Reproduction - April 27, 2017 Category: Molecular Biology Source Type: research

Establishment of a model of superimposed pre-eclampsia in the pregnant stroke prone spontaneously hypertensive rat by exposure to angiotensin II
This study aimed to establish a novel model of superimposed pre-eclampsia in stroke prone spontaneously hypertensive (SHRSP) rats by increasing systemic angiotensin II (AngII) during pregnancy.
Source: Placenta - August 30, 2017 Category: Reproduction Medicine Authors: Hannah Morgan, Elaine Butler, Elisabeth Beattie, Martin McBride, Delyth Graham Source Type: research

Safety of Pregnancy After Cerebral Venous Thrombosis Brief Report
Conclusions—In women with prior cerebral venous thrombosis, recurrent venous thrombotic events during subsequent pregnancies are infrequent.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Diana Aguiar de Sousa, Patricia Canhao, Isabelle Crassard, Jonathan Coutinho, Antonio Arauz, Adriana Conforto, Yannick Beȷot, Maurice Giroud, Jose M. Ferro, on behalf of the ISCVT–2–PREGNANCY Investigators* Tags: Pregnancy, Secondary Prevention, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research

Stroke Volume Recruitability during the Third Trimester of Pregnancy
Conclusion In healthy term pregnancy, the heart operates in the ascending portion of the Starling's curve, rendering it fluid responsive. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - December 26, 2017 Category: Perinatology & Neonatology Authors: Herrera, Sandra Kuhlmann-Capek, Maggie J. Rogan, Sarah C. Saad, Antonio F. Saade, George R. Hankins, Gary D. V. Pacheco, Luis D. Tags: Original Article Source Type: research

AHA: Infections Could Trigger Stroke in Pregnant Women During Delivery
FRIDAY, April 20, 2018 (American Heart Association) -- Pregnant women who have an infection when they enter the hospital for delivery might be at higher risk of having a stroke during their stay, according to new research. The study, published...
Source: Drugs.com - Daily MedNews - April 20, 2018 Category: General Medicine Source Type: news

Stroke Risk Factors Unique to Women
According to this study: Optimal stroke prevention strategies for women should take into account risk factors specific to women, including endogenous hormone levels, exogenous hormone therapy, and pregnancy-related complications.
Source: AJN - April 26, 2018 Category: Nursing Tags: Journal Watch Source Type: research

AHA News: Pregnancy May Raise Risk of Deadliest Type of Stroke
FRIDAY, Feb. 8, 2019 (American Heart Association News) -- The risk of a type of stroke that causes bleeding in the brain is higher among women during pregnancy and in the weeks following delivery, new research finds. While studies have shown that...
Source: Drugs.com - Daily MedNews - February 8, 2019 Category: General Medicine Source Type: news

Hypertensive Disorders of Pregnancy Tied to Stroke Risk
MONDAY, March 4, 2019 -- Women with a history of hypertensive disorders of pregnancy (HDP) have a greater long-term risk for stroke that is reduced by aspirin use, according to a study recently published in Neurology. Eliza C. Miller, M.D., from the...
Source: Drugs.com - Pharma News - March 4, 2019 Category: Pharmaceuticals Source Type: news