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Total 703 results found since Jan 2013.

National registry‐based case–control study: comorbidity and stroke in young adults
ConclusionsIn addition to vascular risk factors, comorbidity (represented by ICD‐10 chapters) was associated with increased risk of stroke in young individuals. The risk of stroke was further increased with the number of diagnosed ICD‐10 chapters.
Source: Acta Neurologica Scandinavica - February 14, 2015 Category: Neurology Authors: E.‐M. Bergman, K. M. Henriksson, S. Åsberg, B. Farahmand, A. Terént Tags: Original Article Source Type: research

Clinical Characteristics of PFO Stroke in Pregnancy (P2.274)
CONCLUSIONS: PFO may pose unique risks compared to non-PFO related stroke in pregnancy. Novel risk factors such as May-Thurner’s anatomy, which promote venous clotting with the increase in abdominal girth are important during pregnancy. For high risk individuals (such as those with known hypercoagulable state), screening for PFO may be of clinical utility in preventing strokes. Further studies are ongoing to validate these preliminary findings. Study Supported by: None.Disclosure: Dr. Chen has nothing to disclose. Dr. Deng has nothing to disclose. Dr. Wickham has nothing to disclose. Dr. McMullin D has nothing to dis...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chen, L., Deng, W., Wickham, T., McMullin D, D., Eng H, L., Buonanno, F., Ning, M. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Patent foramen ovale (PFO), stroke and pregnancy
Patent foramen ovale (PFO)-related stroke is increasingly recognized as an important etiology of ischemic embolic stroke—accounting for up to 50% of strokes previously considered ‘cryptogenic’ or with an unknown mechanism. As a ‘back door to the brain,’ PFO can allow venous clots to enter arterial circulation via interatrial right-to-left shunting, potentially resulting in ischemic stroke. We observe that clinically, PFO-related stroke affects women of childbearing age, and that pregnancy—owing to major changes in hemocoagulative, hormonal, and cardiovascular parameters—can enhance...
Source: Journal of Investigative Medicine - May 23, 2016 Category: Research Authors: Chen, L., Deng, W., Palacios, I., Inglessis-Azuaje, I., McMullin, D., Zhou, D., Lo, E. H., Buonanno, F., Ning, M. Tags: Review Source Type: research

Pregnancy increases stroke risk up to 1 year postpartum and reduces long-term risk
Conclusion: The risk of stroke was elevated during the first year postpartum, but lower in subsequent years. Stroke risk increased in multiparous ( ≥3) women. Physicians should be on alert for pregnancy complications and ensure appropriate management to prevent postpartum stroke.
Source: QJM - January 9, 2017 Category: Internal Medicine Source Type: research

Pregnancy-Related Stroke: A Review
Conclusions and Relevance Early recognition and management are integral in decreasing the morbidity and mortality associated with a stroke in pregnancy. Relevance Statement This study was an evidence-based review of stroke in pregnancy and how to diagnose and mange a pregnancy complicated by a stroke. Target Audience Obstetricians and gynecologist, family physicians Learning Objectives After completing this learning activity, the participant should be better able to identify the pregnancy-related risk factors for a stroke; explain the presenting signs and symptoms of a stroke in pregnancy; describe...
Source: Obstetrical and Gynecological Survey - June 1, 2022 Category: OBGYN Tags: CME ARTICLES Source Type: research

Recurrence of stroke amongst women of reproductive age: impact of and on subsequent pregnancies
ConclusionThe recurrence of stroke after pregnancy is very low, which should be considered when counseling these patients.
Source: European Journal of Neurology - February 1, 2015 Category: Neurology Authors: A. Cruz‐Herranz, I. Illán‐Gala, P. Martínez‐Sánchez, B. Fuentes, E. Díez‐Tejedor Tags: Original Article Source Type: research

Timing and Risk Factors of Postpartum Stroke.
CONCLUSION: Although patients with chronic hypertension and hypertensive diseases of pregnancy are at higher risk of postpartum stroke, they account for a minority of such strokes. The majority of readmissions for postpartum stroke occur within 10 days of discharge; optimal blood pressure management may be particularly important during this period. PMID: 29215510 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - December 4, 2017 Category: OBGYN Authors: Too G, Wen T, Boehme AK, Miller EC, Leffert LR, Attenello FJ, Mack WJ, DʼAlton ME, Friedman AM Tags: Obstet Gynecol Source Type: research

Increased risk of ischaemic stroke among patients with multiple sclerosis
ConclusionsMultiple sclerosis is declared to be associated with an increased risk in developing stroke, which requires closer attention to this group of patients for stroke prevention, especially in the younger population.
Source: European Journal of Neurology - November 29, 2014 Category: Neurology Authors: C.‐H. Tseng, W.‐S. Huang, C.‐L. Lin, Y.‐J. Chang Tags: Original Article Source Type: research

Pre-Pregnancy Obesity and Associations with Stroke and Myocardial Infarction in Women in the Years after Childbirth: A Nationwide Cohort Study.
CONCLUSIONS: In apparently healthy women of fertile age, obesity was associated with increased risks of ischemic stroke and myocardial infarction. PMID: 24146252 [PubMed - as supplied by publisher]
Source: Circulation - October 21, 2013 Category: Cardiology Authors: Dalgas Schmiegelow M, Andersson C, Kober L, Skøtt Andersen S, Bjerring Olesen J, Jensen TB, Azimi A, Birgitte Nielsen M, Gislason G, Torp-Pedersen C Tags: Circulation Source Type: research

Stroke Outcomes and Usage of IV Alteplase during Pregnancy in the Nationwide Inpatient Sample 2005-2010 (P3.100)
ConclusionsStroke remains a serious complication in pregnancy, and mortality is increasing. Usage of tPA for AIS during pregnancy is minimal, with increased mortality compared to all strokes in pregnancy. Research efforts are needed to improve stroke outcomes during pregnancy.Disclosure: Dr. Ouyang has nothing to disclose. Dr. Knopf has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Lee has nothing to disclose. Dr. Smit has nothing to disclose. Dr. Kuklina has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Song, S., Ouyang, B., Knopf, T., Conners, J., Cutting, S., Lee, V., Smit, L., Kuklina, E. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research

Risk of Pregnancy-Associated Stroke Across Age Groups: Population-Based Data from New York State (I5.005)
Conclusions: Younger peripartum women, but not older women, are at increased risk of stroke compared to non-pregnant contemporaries. These results suggest that pregnancy itself does not increase the risk of stroke in older women, though they could reflect a tendency for older pregnant women to have above-average cardiovascular health. More research is needed to investigate why younger women may have increased risk of PAS.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Colello has nothing to disclose. Dr. Leffert ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Colello, A., Leffert, L., Elkind, M., Willey, J. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

Sex Dimorphisms in Ischemic Stroke: From Experimental Studies to Clinic
Sex dimorphisms are important factors that influence the outcomes after ischemic stroke, which include basic health status, cerebrovascular anatomy, hormone levels, and unique factors such as pregnancy and menopause. It is widely recognized that male and female respond differently to stroke. Women aged 45–74 years old showed a lower risk of stroke incidence compared to age-matched man. This kind of protection is lost with aging. Hence, there is increasing requirement to get a more comprehensive understanding of sex-based factors to stroke on stroke incidence, symptoms, and treatments. This review focuses on sex-specific ...
Source: Frontiers in Neurology - June 18, 2020 Category: Neurology Source Type: research

Pharmacists Act on Care Transitions in Stroke (PACT-Stroke): A Systems Approach
This study was a single-center, retrospective assessment of patients contacted by a pharmacist. All data were analyzed descriptively. Our initial evaluation of the Pharmacists Act on Care Transitions in Stroke (PACT-Stroke) service was to quantify and categorize drug-related problems (DRPs), which included drug selection, drug form, dose selection, treatment duration, dispensing, drug use process, patient-related problems, and other. Patients were included if they were adults who experienced an ischemic stroke. Exclusion criteria for this service included pediatric patients, patients with hemorrhagic strokes, patients with...
Source: Clinical Therapeutics - February 16, 2022 Category: Drugs & Pharmacology Authors: Jenna L Harris Danielle DelVecchio Robert W Seabury Christopher D Miller Elizabeth Phillips Source Type: research

Trends in the Incidence and Risk Factors of Pregnancy-Associated Stroke
The objective of this review is to summarize studies on time trends of PAS in relation to trends in the prevalence of stroke risk factors in pregnant women. Seven retrospective national healthcare register-based cohort studies from the US, Canada, UK, Sweden, and Finland were identified. Five studies from the US, Canada, and Finland reported an increasing trend of PAS. Potential biases include more sensitive diagnostics and improved stroke awareness among pregnant women and professionals toward the end of the study period. However, the concurrent increase in the prevalence of several stroke risk factors among pregnant wome...
Source: Frontiers in Neurology - April 11, 2022 Category: Neurology Source Type: research