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Infectious Disease: Outbreaks

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Science ’s 2022 Breakthrough of the Year: A telescope’s golden eye sees the universe anew
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Source: ScienceNOW - December 15, 2022 Category: Science Source Type: news

Role of Inflammaging on the Reproductive Function and Pregnancy
AbstractDuring female lifetime and pregnancy, inflammation and cellular senescence are implicated in physiological processes, from ovulation and menstruation, to placental homeostasis and delivery. Several lifestyles, nutritional, and environmental insults, as well as long-lasting pregestational inflammatory diseases may lead to detrimental effects in promoting and sustaining a chronic excessive inflammatory response and inflammaging, which finally contribute to the decay of fertility and pregnancy outcome, with a negative effect on placental function, fetal development, and future health risk profile in the offspring. Mal...
Source: Clinical Reviews in Allergy and Immunology - January 15, 2022 Category: Allergy & Immunology Source Type: research

Johnson & Johnson Joins World Health Organization in Efforts to Prevent Spread of Ebola in West Africa
Discussions are ongoing with the U.S. Food and Drug Administration regarding the approval of the vaccine regimen in the U.S. WHO Prequalification is often a prerequisite for national registrations of new vaccines and medicines in developing countries. Johnson & Johnson now looks forward to collaborating with the WHO’s African Vaccine Regulatory Forum (AVAREF) to progress national registrations of the Company’s Ebola vaccine regimen. The Company’s Ebola vaccine regimen is designed to be used proactively to induce immunity against Ebola virus disease in adults and children. Johnson & Johnson’s Commitment to E...
Source: Johnson and Johnson - May 13, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

On endocrine disruption at the workplace – how to get from suggestive to conclusive evidence?
Unusual clusters and outbreaks of reproductive disorders during past decades remind us of the devastating health consequences and human suffering to which exposure to industrial chemicals and pharmaceuticals may give rise. Birth defects caused by gestational exposure to thalidomide, vaginal cancer by diethylstilbestrol, azoospermia by dibromochloropropane, cerebral palsy by methyl mercury, and fetal wasting syndrome by chlorinated biphenyls are all inscribed in medical history as tragic mementos of ignorance and neglect in the past (1). In parallel with the fast-increasing entrance of women into the workforce, interest ...
Source: Scandinavian Journal of Work, Environment and Health - April 16, 2020 Category: Occupational Health Tags: Editorial Source Type: research

All Your Coronavirus Questions, Answered
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide. A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illn...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized COVID-19 Explainer Source Type: news

Is It Allergies, The Flu Or The Coronavirus? How To Tell The Difference
(CNN) — The coronavirus has infected more than 100,000 people worldwide. With all of the news of event cancellations, empty flights and health precautions (wash your hands!), it’s natural that people may get a little anxious every time they feel a tickle in their throat or the beginnings of a bad cough. While the coronavirus is certainly something to take seriously, the chances of any individual person getting it are still low. But if you’re wondering whether that stuffy nose could end up being a worst case scenario, CNN talked to Dr. Greg Poland, a professor of medicine and Infectious diseases at the May...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 11, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Coronavirus Source Type: news

That & #039;s a First: FDA Tackles STDs, Zika, and Prosthetic Joint Infection
The U.S. diagnostic market celebrated three regulatory firsts last week.  1. FDA Authorizes Marketing of First Zika Test Until now, tests for detecting Zika virus immunoglobulin (IgM) antibodies in blood were only authorized for emergency use under FDA's Emergency Use Authorization (EUA) authority. On Thursday, the agency said it has authorized marketing of the ZIKV Detect 2.0 IgM Capture ELISA under the agency's traditional premarket authority. The test is manufactured by InBios International. “At the onset of the Zika virus outbreak, when little was known about the disease or how...
Source: MDDI - May 24, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance IVD Source Type: news

The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses
In this study, we exposed apically well-differentiated human NECs cultured at the ALI to the related flaviviruses ZIKV, JEV, WNV, and Usutu virus (USUV). We selected these viruses due to the recent increasing evidences of potential threat to humans (Cadar et al., 2017; Simonin et al., 2018). We show that NECs are particularly susceptible to JEV and WNV infection and to other flaviviruses included in this study. Infection with each virus led to shedding of infectious virus particles through the apical and basolateral surfaces and triggered host mechanisms at the level of inflammatory and antiviral mediators....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research

Scientists Start Second Phase Of Zika Vaccine Testing
Researchers at Houston’s Baylor College of Medicine last week began Phase 2 clinical trials for a Zika vaccine that is expected to have results as early as the end of this year.  Andrew Pekosz, a professor of microbiology and immunology at Johns Hopkins University’s Bloomberg School of Public Health, praised the vaccine’s potential to prevent disease, as well as how quickly clinical trials have taken place.  “It’s really been a light-speed endeavor,” Pekosz, who was not involved in the vaccine’s testing or development at the National Institute for Allergy and In...
Source: Science - The Huffington Post - April 3, 2017 Category: Science Source Type: news

5 Ways The Zika Virus Is Here To Stay
Zika virus’ status as a global health threat may officially be over, but the disease’s impact is far from contained.  The World Health Organization decided in November to end its designation of Zika virus as a public health emergency, but that doesn’t mean that Zika virus has disappeared, explained Dr. Carlos Pardo-Villamizar, a clinical neurologist with an expertise in infectious disorders at Johns Hopkins Medicine. Alongside pressing concerns about how to prevent a resurgence of the disease, health care systems in Brazil and other countries that saw births of babies infected with the disease in ute...
Source: Science - The Huffington Post - January 4, 2017 Category: Science Source Type: news

Health Official Warns Zika Could Spread Across U.S. Gulf
Aug 21 (Reuters) - One of the top U.S. public health officials on Sunday warned that the mosquito-borne Zika virus could extend its reach across the U.S. Gulf Coast after officials last week confirmed it as active in the popular tourist destination of Miami Beach. The possibility of transmission in Gulf States such as Louisiana and Texas will likely fuel concerns that the virus, which has been shown to cause the severe birth defect known as microcephaly, could spread across the continental United States, even though officials have played down such an outcome. Concern has mounted since confirmation that Zika has expanded in...
Source: Healthy Living - The Huffington Post - August 21, 2016 Category: Consumer Health News Source Type: news

Lawmakers Enjoy Vacation While Zika Spreads To U.S.
WASHINGTON ― Democrats in Congress called on leaders Friday to interrupt a seven-week vacation and return to Capitol Hill after the first local outbreak of the Zika virus was reported in Florida. Congress failed to pass emergency legislation to fund the nation’s response to Zika before legislators departed earlier this month, first to attend the party conventions and then to take time off. But with news that at least four people had contracted Zika locally in Southern Florida and the conventions over, Democrats were quick to say it’s time to come back to work. “I call on Republican Congressional leaders...
Source: Healthy Living - The Huffington Post - July 29, 2016 Category: Consumer Health News Source Type: news

Zika Virus Infection: Current Concerns and Perspectives
Abstract The Zika virus outbreaks highlight the growing importance need for a reliable, specific and rapid diagnostic device to detect Zika virus, as it is often recognized as a mild disease without being identified. Many Zika virus infection cases have been misdiagnosed or underreported because of the non-specific clinical presentation. The aim of this review was to provide a critical and comprehensive overview of the published peer‐reviewed evidence related to clinical presentations, various diagnostic methods and modes of transmission of Zika virus infection, as well as potential therapeutic targets to combat...
Source: Clinical Reviews in Allergy and Immunology - May 27, 2016 Category: Allergy & Immunology Source Type: research