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Hospitalists Join in Sustainability Efforts
Ms. Wohlford is the director of sustainability for Carilion Clinic. The Roanoke, Va.-based health system has numerous awards and recognitions for its sustainability efforts that include everything from installing solar-power receptors to hiring sheep to keep the lawn. Carilion Clinic. In a world transformed by environmental degradation and the effects of climate change, hospitals can be major generators of greenhouse gases, energy consumption, and waste. But they are also important centers for health and wellness promotion, not just for the patients they serve but also for staff and their communities. That is why a growi...
Source: The Hospitalist - October 3, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Practice Management Source Type: research

Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions
Conclusions and Future Perspectives It is now evident that NK/ILC family plays a pivotal role in the immune defenses. Recent studies in murine and human settings demonstrated that the expression of several inhibitory checkpoints, that may be detrimental in the tumor context, is not restricted to T lymphocytes, revealing an important, yet poorly appreciated, contribution of their expression on innate immune cells. Thus, in the recent years different immunotherapy approaches, based on the blockade of inhibitory NK cell receptors, have been developed in order to unleash NK cell cytotoxicity. This is particularly important in...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research

Short- and long-term impact of remifentanil on thermal detection and pain thresholds after cardiac surgery: A randomised controlled trial
CONCLUSION Earlier reports of increased pain sensitivity 1 year after the use of remifentanil could not be confirmed in this randomised study using Quantitative Sensory Testing. This indicates that remifentanil plays a minor role in the development of chronic thoracic pain. Still, the relatively high incidence of chronic thoracic pain and its accompanying impact on quality of life remain challenging problems. TRIAL REGISTRATION The study was registered at EudraCT (ref: 2013-000201-23) and ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT02031016).
Source: European Journal of Anaesthesiology - December 7, 2018 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Maternal Exposure of BALB/c Mice to Indoor NO2 and Allergic Asthma Syndrome in Offspring at Adulthood with Evaluation of DNA Methylation Associated Th2 Polarization
Conclusions: Maternal exposure to indoor environmental NO2 causes allergic asthma-related consequences in offspring absent any subsequent lung provocation and potentiates the symptoms of allergic asthma in adult offspring following postnatal allergic sensitization and challenge; this response is associated with the Th2-based immune response and DNA methylation of the IL4 gene. https://doi.org/10.1289/EHP685 Received: 19 June 2016 Revised: 07 June 2017 Accepted: 19 June 2017 Published: 13 September 2017 Address correspondence to N. Sang, College of Environment and Resource, Shanxi University, Taiyuan, Shanxi 030006, P...
Source: EHP Research - September 13, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Doxycycline for outpatient-treated acute exacerbations of COPD: a randomised double-blind placebo-controlled trial
Publication date: Available online 5 May 2017 Source:The Lancet Respiratory Medicine Author(s): Patricia van Velzen, Gerben ter Riet, Paul Bresser, Jeroen J Baars, Bob T J van den Berg, Jan W K van den Berg, Paul Brinkman, Jennece W F Dagelet, Johannes M A Daniels, Dewi R G L Groeneveld-Tjiong, René E Jonkers, Coen van Kan, Frans H Krouwels, Karin Pool, Arjan Rudolphus, Peter J Sterk, Jan M Prins Background Antibiotics do not reduce mortality or short-term treatment non-response in patients receiving treatment for acute exacerbations of COPD in an outpatient setting. However, the long-term effects of antibiotics are unkn...
Source: The Lancet Respiratory Medicine - May 6, 2017 Category: Respiratory Medicine Source Type: research

Maternal Asthma, Pregnancy, Delivery and Birth Outcomes: A Retrospective Cohort Study.
Abstract The aim of current study was to determine women´s maternal asthma in pregnancy, delivery and birth outcomes. Using a retrospective cohort design, data of 580 pregnant women were gathered form a large teaching hospital in Tehran, Iran. The medical records of pregnant women who had attended this hospital between 2009 and 2011 were assessed. Data of delivery and birth outcomes were gathered by observation and medical records of women. Multiple logistic regression and adjusted odds ratio (OR) were used to assess the independent association of asthma and outcomes. 274 patients (47.2%) were in "asthmatic group...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2017 Category: Allergy & Immunology Authors: Vaezi A, Haghighi L, Beigmohammadi F, Nojomi M Tags: Iran J Allergy Asthma Immunol Source Type: research

4th Pediatric Allergy and Asthma Meeting (PAAM)
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut mic...
Source: Clinical and Translational Allergy - October 31, 2016 Category: Allergy & Immunology Source Type: research

Title: The WASH Approach: Fighting Waterborne Disease in Emergency Situations
Refugees collect water from a public tap stand in an Adjumani settlement. © Wendee Nicole Rhino Camp, Arua District. Refugees in Uganda live on land donated by Ugandan nationals. Refugee families are given plots on which they can build temporary shelters and grow crops.© Wendee Nicole Oxfam staff members Tim Sutton (left) and Pius Nzuki Kitonyi (right) with the soon-to-be-repaired water pump in Adjumani. In disaster-affected situations, Oxfam takes a lead in delivering WASH-related services.© Wendee Nicole Hand-operated water pumps are a reliable source of pre...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Community Health Disaster Response Drinking Water Quality Infectious Disease Infrastructure International Environmental Health Microbial Agents Sanitation Warfare and Aftermath Water Pollution Source Type: research