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Specialty: General Medicine
Condition: Polymyositis

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Total 16 results found since Jan 2013.

An atypical presentation of hypothyroidism with extremely exaggerated functional impairment
We report a 34-year-old woman, presenting with a new atypical musculoskeletal manifestation of hypothyroidism mimicking polymyositis.
Source: Clinical Case Reports - July 19, 2023 Category: General Medicine Authors: Alireza Arezoumand, Sahar Nazari, Kimia Jazi, Mohammad Bagherzade, Mohammad Mehdi Riahi, Melika AkbariMehr, Narges Kanganee, Maryam Masoumi Tags: CASE REPORT Source Type: research

Acute respiratory distress syndrome relapsing in 10  months with an initial manifestation of polymyositis
We report a case of a patient with steroid-responsive ARDS that relapsed in 10  months with an initial manifestation of seronegative polymyositis. ARDS associated with polymyositis may develop earlier than myopathy and may relapse later.
Source: Clinical Case Reports - December 6, 2021 Category: General Medicine Authors: Yukihisa Takeda, Mariko Ono, Hayato Kinoshita, Yoko Nagatomo, Hiroki Miyauchi, Hiroshi Tsukamoto, Hiroyuki Nakamura, Kazutetsu Aoshiba Tags: CASE REPORT Source Type: research

Strength training and aerobic exercise training for muscle disease.
CONCLUSIONS: The evidence regarding strength training and aerobic exercise interventions remains uncertain. Evidence suggests that strength training alone may have little or no effect, and that aerobic exercise training alone may lead to a possible improvement in aerobic capacity, but only for participants with FSHD. For combined aerobic exercise and strength training, there may be slight increases in muscle strength and aerobic capacity for people with dermatomyositis and polymyositis, and a slight decrease in aerobic capacity and increase in muscle strength for people with juvenile dermatomyositis. More research with rob...
Source: Cochrane Database of Systematic Reviews - December 5, 2019 Category: General Medicine Authors: Voet NB, van der Kooi EL, van Engelen BG, Geurts AC Tags: Cochrane Database Syst Rev Source Type: research

Antisynthetase syndrome presenting as interstitial lung disease: a case report
ConclusionAntisynthetase syndrome is a rare clinical entity which apart from clinical presentation requires specific serological investigations for diagnosis. Concomitant association of interstitial lung disease gives it a guarded prognosis.
Source: Journal of Medical Case Reports - August 3, 2019 Category: General Medicine Source Type: research

18FFluorodeoxyglucose positron emission tomography/computed tomography for diagnosing polymyositis/dermatomyositis.
Authors: Sun L, Dong Y, Zhang N, Lv X, Chen Q, Wei W Abstract [18F]fluorodeoxyglucose positron emission tomography/computed tomography ([18F]FDG-PET/CT) is useful for diagnosing cancers and inflammatory diseases. A polymyositis/dermatomyositis (PM/DM) lesion is an inflammatory heterogeneous disease of the striated muscle. In the present study, the maximum standardized uptake value (SUVmax) was compared between 22 cases with definite or probable PM/DM (PM/DM group) that underwent [18F]FDG-PET/CT examination and the same number of patients with no myopathy. The average proximal muscle FDG uptake value (SUVaverage) fo...
Source: Experimental and Therapeutic Medicine - May 30, 2018 Category: General Medicine Tags: Exp Ther Med Source Type: research

Hypokalemic myopathy in primary aldosteronism: A case report.
Authors: Wu C, Xin J, Xin M, Zou H, Jing L, Zhu C, Lei W Abstract Primary aldosteronism (PA) is a rare disorder. The majority of patients with PA present with typical features and are easily diagnosed. This disorder is usually diagnosed with hypokalemia, hypertension or an adrenal mass. However, patients with atypical symptoms may present a challenge for diagnosis and treatment. In the present study, a case of PA is described that presented with hypokalemic myopathy simulating polymyositis. The patient was a 44-year-old woman who presented with weakness and difficulty walking. The patient was initially suspected to...
Source: Experimental and Therapeutic Medicine - January 20, 2017 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Insight into the training of patients with idiopathic inflammatory myopathy.
Abstract Using current recommended treatment, a majority of patients with idiopathic inflammatory myopathy develop muscle impairment and poor health. Beneficial effects of exercise have been reported on muscle performance, aerobic capacity and health in chronic polymyositis and dermatomyositis, as well as in active disease and inclusion body myositis to some extent. Importantly, randomized controlled trials indicate that improved health and decreased clinical disease activity could be mediated through increased aerobic capacity. Recently, reports seeking pathomechanisms of the underlying effects of exercise on ske...
Source: Orvosi Hetilap - August 31, 2016 Category: Journals (General) Authors: Váncsa A Tags: Orv Hetil Source Type: research

New insights of myositis-specific and -associated autoantibodies in juvenile and adult type myositis.
Abstract Myositis, which means inflammation of the muscles, is a general term used for inflammatory myopathies. Myositis is a rare idiopathic autoimmune disease. It is believed that environmental factors such as virus, bacteria, parasites, direct injuries, drugs side effect can trigger the immune system of genetically susceptible individuals to act against muscle tissues. There are several types of myositis with the same systemic symptoms such as muscle weakness, fatigue, muscle pain and inflammation. These include dermatomyositis, juvenile dermatomyositis, inclusion-body myositis, polymyositis, orbital myositis a...
Source: Orvosi Hetilap - June 30, 2016 Category: Journals (General) Authors: Váncsa A, Dankó K Tags: Orv Hetil Source Type: research

Anti-U3 ribonucleoprotein antibody-positive inflammatory myopathy: a case report
Conclusions Our findings indicate that mild muscle weakness with steroid-resistant dysphagia may be a clinical feature of patients with anti-U3 RNP antibody-positive inflammatory myopathy.
Source: Journal of Medical Case Reports - June 8, 2016 Category: Journals (General) Source Type: research

Long-term follow-up of patients with idiopathic inflammatory myopathy at Waitemata District Health Board.
CONCLUSION: There is significant treatment-related morbidity in adult IIM, with a high incidence of steroidrelated complications, in particular, osteoporosis. Infections accounted for the most common cause of death. PMID: 26914299 [PubMed - as supplied by publisher]
Source: New Zealand Medical Journal - February 26, 2016 Category: Journals (General) Tags: N Z Med J Source Type: research

Epidemiology of idiopathic inflammatory myopathy in Hungary.
CONCLUSIONS: The authors propose to establish a National Myositis Registry in the frame of multicentric collaboration in order to have more information about the disease. Orv. Hetil., 2014, 155(41), 1643-1646. PMID: 25282109 [PubMed - in process]
Source: Orvosi Hetilap - October 1, 2014 Category: Journals (General) Authors: Nagy-Vincze M, Bodoki L, Griger Z, Dankó K Tags: Orv Hetil Source Type: research

Electrophysiological and Clinical Examination of Polymyositis: A Retrospective Analysis.
CONCLUSIONS:: Our results show that MUP is a sensitive yardstick for diagnosis of PM and is inversely related to disease duration. Our study also highlights that selecting specific muscles for EMG may improve diagnostic accuracy in PM. PMID: 24556930 [PubMed - as supplied by publisher]
Source: The American Journal of the Medical Sciences - February 19, 2014 Category: Journals (General) Authors: Yang F, Jing F, Chen Z, Ling L, Wang R, Wang X, Tin C, Pu C, Shi X, Huo Y, Zhang X, Huang X, Yu S Tags: Am J Med Sci Source Type: research

Antisynthetase syndrome: Not just an inflammatory myopathy
In recent years, antisynthetase syndrome has been recognized as an important cause of autoimmune inflammatory myopathy in a subset of patients with polymyositis and dermatomyositis. It is associated with serum antibodies to aminoacyl-transfer RNA synthetases and is characterized by a constellation of manifestations, including fever, myositis, interstitial lung disease, "mechanic’s hands," Raynaud phenomenon, and polyarthritis. Physicians should be familiar with its variety of clinical presentations and should include it in the differential diagnosis in patients presenting with unexplained interstitial lung disease.
Source: Cleveland Clinic Journal of Medicine - October 1, 2013 Category: Journals (General) Authors: CHATTERJEE, S., PRAYSON, R., FARVER, C. Tags: Review Source Type: research

Strength training and aerobic exercise training for muscle disease.
CONCLUSIONS: Moderate-intensity strength training in myotonic dystrophy and FSHD and aerobic exercise training in dermatomyositis and polymyositis and myotonic dystrophy type I appear to do no harm, but there is insufficient evidence to conclude that they offer benefit. In mitochondrial myopathy, aerobic exercise combined with strength training appears to be safe and may be effective in increasing submaximal endurance capacity. Limitations in the design of studies in other muscle diseases prevent more general conclusions in these disorders. PMID: 23835682 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 9, 2013 Category: Journals (General) Authors: Voet NB, van der Kooi EL, Riphagen II, Lindeman E, van Engelen BG, Geurts AC Tags: Cochrane Database Syst Rev Source Type: research

Statin-Associated Polymyositis Following Omeprazole Treatment.
Abstract Statins are an extensively used class of drugs, and myopathy is an uncommon, but well-described side effect of statin therapy. Inflammatory myopathies, including polymyositis, dermatomyositis, and necrotizing autoimmune myopathy, are even rarer, but debilitating, side effects of statin therapy that are characterized by the persistence of symptoms even after discontinuation of the drug. It is important to differentiate statin-associated inflammatory myopathies from other self-limited myopathies, as the disease often requires multiple immunosuppressive therapies. Drug interactions increase the risk of stati...
Source: Clinical Medicine and Research - April 12, 2013 Category: Journals (General) Authors: Kanth R, Shah MS, Flores RM Tags: Clin Med Res Source Type: research