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Specialty: Neurosurgery
Condition: Atrial Fibrillation

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Total 221 results found since Jan 2013.

Endovascular thrombectomy and left atrial appendage evaluation for recurrent cerebral embolism case with atrial fibrillation early after administration of intravenous tissue plasminogen activator
ConclusionsAttention should be paid to ischemic stroke recurrence as a complication of IV t-PA, and preparation for mechanical thrombectomy is warranted. Further study of the left atrial appendage is needed to clarify the mechanisms of onset.
Source: Interdisciplinary Neurosurgery - November 9, 2019 Category: Neurosurgery Source Type: research

E-023 Predictors of outcomes in tandem anterior circulation occlusions following mechanical thrombectomy
In this study, we present outcomes of patients undergoing tandem mechanical thrombectomy. We demonstrate that stenting is associated with improved final reperfusion, but increased odds of asymptomatic ICH. Additional clinical trials should be performed to optimize the procedure and improve patient outcomes.Disclosures J. Catapano: None. D. Farhadi: None. A. Naik: None. S. Koester: None. E. Winkler: None. V. Srinivasan: None. K. Karahalios: None. J. Rulney: None. S. Desai: None. A. Jadhav: None. F. Albuquerque: None. A. Ducruet: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Catapano, J., Farhadi, D., Naik, A., Koester, S., Winkler, E., Srinivasan, V., Karahalios, K., Rulney, J., Desai, S., Jadhav, A., Albuquerque, F., Ducruet, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Intravenous thrombolysis before mechanical thrombectomy in patients with atrial fibrillation
The introduction into clinical practice of endovascular mechanical thrombectomy (MT) has brought better results in patients with ischemic stroke from large vessel occlusion (LVO) in the anterior circulation in whom therapy is started 4.5–5 hours after symptoms onset.1–3 Controversies exist about the usefulness of intravenous thrombolysis (IVT) before MT in patients with atrial fibrillation (AF). AF is the probable etiology in >25% of ischemic strokes, and >40% of patients with ischemic stroke from LVO in the anterior circulation have a clinical history of AF.4 5 AF is an independent predictor of poor func...
Source: Journal of NeuroInterventional Surgery - July 14, 2023 Category: Neurosurgery Authors: Bozzani, A., Arici, V., Ragni, F., Sterpetti, A., Arbustini, E. Tags: Letter Source Type: research

O-042 Functional Outcome Prediction Model for Carotid Stenting Patients Using Admission Profiles: 29,453 patients using NIS data 2005 to 2013
ConclusionsAge (greater than 80), presence of symptoms including TIA, DM, CHF, COPD and CRF were identified to predict worse functional outcome after CAS.DisclosuresS. Park: None. M. Alexander: 1; C; : Investigator in CREST2 Trial. A. Rosengart: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Park, S., Alexander, M., Rosengart, A. Tags: Oral abstracts Source Type: research

A case of cardiac tamponade during the treatment of simultaneous cardio-cerebral infarction associated with atrial fibrillation - Case report.
Conclusion: Some cases with CCI treated with IV-tPA and endovascular intervention were reported, but the treatment strategy should be still discussed multidisciplinary. Especially, the administration of antithrombotic drugs for CCI should be carefully performed because fatal hemorrhage such as cardiac tamponade can occur. PMID: 31893142 [PubMed]
Source: Surgical Neurology International - January 2, 2020 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Dabigatran, intracranial hemorrhage, and the neurosurgeon.
Abstract Dabigatran etexilate (Pradaxa) is a novel oral anticoagulant that has gained FDA approval for the prevention of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation. In randomized trials, the incidence of hemorrhagic events has been demonstrated to be lower in patients treated with dabigatran compared with the traditional anticoagulant warfarin. However, dabigatran does not have reliable laboratory tests to measure levels of anticoagulation and there is no pharmacological antidote. These drawbacks are challenging in the setting of intracerebral hemorrhage. In this article...
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Awad AJ, Walcott BP, Stapleton CJ, Yanamadala V, Nahed BV, Coumans JV Tags: Neurosurg Focus Source Type: research

Spontaneous Cerebellar Hemorrhage in a Patient Taking Apixaban
Conclusions Recent FDA approval of several novel oral anticoagulants for use in patients with atrial fibrillation has resulted in a significant number of patients formerly treated with warfarin being switched to these newer agents. There remains a lack of clear guidelines for the management of hemorrhagic complications. This case report describes one management strategy and highlights the paucity of current evidence to support critical clinical decisions.
Source: Interdisciplinary Neurosurgery - December 24, 2014 Category: Neurosurgery Source Type: research

Rivaroxaban and intracranial haemorrhage after mild traumatic brain injury: A dangerous combination?
The novel direct anticoagulant rivaroxaban has been approved in 2011 for the prophylaxis of thromboembolic events in patients with atrial fibrillation. Its mechanisms of action involve direct inhibition of factor Xa and a large multicentre trial has demonstrated at least non-inferiority compared with warfarin regarding the prevention of ischemic stroke [1]. This trial has also demonstrated that the risk of major bleeding was not increased with rivaroxaban and indeed, intracranial and fatal bleeding occurred less frequently in rivaroxaban-treated patients.
Source: Clinical Neurology and Neurosurgery - May 30, 2015 Category: Neurosurgery Authors: Christopher Beynon, Anna Potzy, Oliver W. Sakowitz, Andreas W. Unterberg Source Type: research

P-016 role of balloon guiding catheter in mechanical thrombectomy using stentretrivers subgroup analysis of swift prime
ConclusionBGC use in the SWIFT PRIME cohort of patients treated with rTPA and mechanical thrombectomy with Solitaire demonstrated significantly lower infarct size and higher reperfusion rates at 27 h. Overall procedure times were shorter for BGC group. These findings suggest that there is likely benefit from use of BGC when treating AIS with mechanical thrombectomy; however, randomized trials are required to confirm this finding.Abstract P-016 Table 1Distribution of variables among BGC and no BGC group Characteristic No BGC BGC Total p-value Number394887Age (years)61.8 ± 13.566.8 ± 11.764.6 ± 12....
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Pereira, V., Siddiqui, A., Jovin, T., Yavagal, D., Levy, E., Bonafe, A., Cognard, C., Jansen, O., Nogueira, R., Jahan, R., Slater, L., Coutinho, J., Saver, J., Goyal, M. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

Effect of Carotid Revascularization Endarterectomy Versus Stenting Trial Results on the Performance of Carotid Artery Stent Placement and Carotid Endarterectomy in the United States
BACKGROUND: CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) results, published in 2010, showed no difference in the rates of composite outcome (stroke, myocardial infarction, or death) between carotid artery stent placement (CAS) and carotid endarterectomy (CEA). OBJECTIVE: To identify any changes in use and outcomes of CAS and CEA subsequent to the CREST results. METHODS: We estimated the frequency of CAS and CEA procedures in the years 2009 (pre-CREST period) and 2011 (post-CREST period), using data from the National Inpatient Sample (NIS). Demographic and clinical characteristics and in-hospital o...
Source: Neurosurgery - October 22, 2015 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

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Every 3 seconds, someone in the United States needs blood, and it is estimated that 1 in 20 Americans will receive a transfusion at some point in their lives. This demand for blood will increase further as the population ages, as>40% of all donated blood currently is used in people>65 years old. In addition, an increasing number of individuals take oral anticoagulants (OACs) and antiplatelet agents for cardiac reasons (e.g., atrial fibrillation or valvular disease), for stroke prevention, or for management of venous thromboembolism.
Source: World Neurosurgery - March 29, 2016 Category: Neurosurgery Authors: Peter Le Roux Tags: Book Review Source Type: research

Efficacy of Proximal Aspiration Thrombectomy for Using Balloon-Tipped Guide Catheter in Acute Intracranial Internal Carotid Artery Occlusion.
CONCLUSION: A strategy of PAT before standard MT may result in shorter puncture-to-reperfusion time and better angiographic outcome than a strategy of standard MT for acute intracranial ICA occlusion. PMID: 27446520 [PubMed]
Source: Journal of Korean Neurosurgical Society - July 26, 2016 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

O-022 General Anesthesia, Baseline ASPECTS, Time to Treatment, and IV TPA Impact Intracranial Hemorrhage after Stentriever Thrombectomy: Pooled Analysis from SWIFT PRIME, SWIFT and STAR Trials
ConclusionsHigher baseline ASPECTS, better collaterals and general anesthesia are associated with lower incidence of ICH after neurothrombectomy with Solitaire stentriever. Prolonged time to treatment increases the risk of parenchymal hematoma and hemorrhage in ischemic territory. Parenchymal hematoma is distinctly associated with IV TPA. Of all ICH subtypes, sICH has the strongest impact on functional independence.DisclosuresR. Raychev: None. J. Saver: 2; C; Medtronic, Stryker, Boehrniger, Neuravia. R. Jahan: 1; C; Medtronic. 2; C; Medtronic. R. Nogueira: 2; C; Medtronic, Stryker. M. Goyal: 2; C; Medtronic. V. Pereira: 2;...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Raychev, R., Saver, J., Jahan, R., Nogueira, R., Goyal, M., Pereira, V., Gralla, J., Levy, E., Yavagal, D., Cognard, C., Liebeskind, D. Tags: Oral abstracts Source Type: research

Acute hemifield room tilt illusion in cerebral ischaemia
We present 2 cases in the setting of acute vertebrobasilar territory ischaemia. Case 1: A 56-year old man was admitted with acute dyspnoea and new atrial fibrillation. On day two while lying in bed, he developed vomiting and suddenly perceived the curtain to his left was lying horizontal along the floor and felt he was sliding towards the left. MRI brain revealed acute multiterritory infarction (Figure 1). He was commenced on therapeutic anticoagulation and was well on follow-up. Case 2: A 47-year old man awoke with acute vertigo, vomiting and ataxia, exacerbated by head movement with dysarthria and diplopia. The worl...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Kinsella, J., Lonergan, R., Killeen, R., McGuigan, C. Tags: Drugs: CNS (not psychiatric), Stroke, Ophthalmology, Ear, nose and throat/otolaryngology ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

The importance of atrial fibrillation and selected echocardiographic parameters for the effectiveness and safety of thrombolytic therapy in patients with stroke
Publication date: Available online 19 September 2017 Source:Neurologia i Neurochirurgia Polska Author(s): Lasek-Bal Anetta, Kowalewska-Twardela Teresa, Warsz-Wianecka Aldona, Puz Przemysław, Krzan Aleksandra, Cieślik Aleksandra
Source: Polish Journal of Neurology and Neurosurgery - September 20, 2017 Category: Neurosurgery Source Type: research