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Condition: Arrhythmia

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Total 3904 results found since Jan 2013.

Frequency Of Atrial Arrhythmias In Stroke: Prolonged Monitoring Of Cardiac Rhythm For Detection Of Atrial Fibrillation After A Cerebral Ischemic Event (PEAACE) Study (P1.130)
Conclusions: Prolonged cardiac monitoring for detection of atrial arrhythmias increases the yield for PAF. Our study shows that PAF is very common in stroke or TIA patients. There was no significant difference in presentation and risk factor profile of patients with less than or more than 30 seconds PAF. The arbitrary 30 seconds duration rule may have to be reconsidered.Disclosure: Dr. Ibrahim has nothing to disclose. Dr. Basir has nothing to disclose. Dr. Ghrooda has nothing to disclose. Dr. Mohammad has nothing to disclose. Dr. Khan has nothing to disclose. Dr. Dobrowolski has nothing to disclose. Dr. Ghualmhusein has no...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ibrahim, Y., Basir, G., Ghrooda, E., Mohammad, A., Khan, N., Dobrowolski, P., Ghualmhusein, S., Shuaib, A. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Miscellaneous Source Type: research

Cerebrovascular Events in 21 105 Patients With Atrial Fibrillation Randomized to Edoxaban Versus Warfarin: Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 Clinical Sciences
Conclusions— In patients with atrial fibrillation, once-daily edoxaban was as effective as warfarin in preventing all strokes, with significant reductions in various subtypes of intracranial bleeding. Ischemic cerebrovascular event rates were similar with high-dose edoxaban and warfarin, whereas low-dose edoxaban was less effective than warfarin. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00781391.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Giugliano, R. P., Ruff, C. T., Rost, N. S., Silverman, S., Wiviott, S. D., Lowe, C., Deenadayalu, N., Murphy, S. A., Grip, L. T., Betcher, J. M., Duggal, A., Dave, J., Shi, M., Mercuri, M., Antman, E. M., Braunwald, E., on behalf of the ENGAGE AF-TIMI 48 Tags: Other anticoagulants, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs Clinical Sciences Source Type: research

Gender and the risk of stroke in atrial fibrillation: impact of old and new anticoagulation regimens
Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia. Thromboembolic events related to AF result in significant morbidity and mortality. An individual’s risk of thromboembolism in the setting of AF varies significantly based on clinical and demographic characteristics. The risk of stroke appears to be greater among women with AF than men. Warfarin provides sufficient protection against stroke, but does not eliminate gender differences in stroke rates. New oral anticoagulants demonstrated similar or superior efficacy compared to warfarin; however rates of stroke in women on new agents remain...
Source: Clinical Research in Cardiology Supplements - April 1, 2013 Category: Cardiology Source Type: research

Clinically important atrial arrhythmia and stroke risk: a UK-wide online survey among stroke physicians and cardiologists
Conclusions: There is a lack of consensus on the diagnosis and management of patients with brief runs of atrial arrhythmia detected on ambulatory ECG. Further research is needed to clarify the risk of stroke in this unique population of patients.
Source: QJM - October 24, 2014 Category: Internal Medicine Authors: Rankin, A. J., Tran, R. T., Abdul-Rahim, A. H., Rankin, A. C., Lees, K. R. Tags: Original papers Source Type: research

Prevalence and impact on outcome of electrocardiographic early repolarization patterns among stroke patients: a prospective observational study
Conclusions ER is frequently found among patients with acute cerebrovascular events and is more prevalent in patients with hemorrhagic compared to ischemic events. Our study yields no evidence that ER is associated with worse outcome or mortality after stroke.
Source: Clinical Research in Cardiology - February 25, 2015 Category: Cardiology Source Type: research

Stroke prevention with rivaroxaban in higher‐risk populations with atrial fibrillation
ConclusionsThese subgroup analyses demonstrate that the treatment effect for rivaroxaban vs. warfarin is broadly consistent across a wide range of patient groups, with respect to both efficacy and safety.
Source: International Journal of Clinical Practice - April 9, 2015 Category: Internal Medicine Authors: H.‐C. Diener, J. L. Halperin, K. Fox, G. J. Hankey Tags: Review Article Source Type: research

Annual atrial tachyarrhythmia burden determined by device interrogation in patients with cardiac implanted electronic devices is associated with a risk of ischaemic stroke independent of known risk factors ADULT CARDIAC
CONCLUSIONS Patients who accumulated an AT duration exceeding 5% (18 days) of the total time in any of the 1-year periods are more likely to have an ischaemic stroke than those who have a low or zero AT burden.
Source: European Journal of Cardio-Thoracic Surgery - April 9, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Wang, S.-H., Kang, Y.-C., Wang, C.-C., Wen, M.-S., Hung, K.-C., Wang, C.-Y., Chen, T.-H. Tags: Electrophysiology - arrhythmias ADULT CARDIAC Source Type: research

A Comparison of Atrial Fibrillation Monitoring Strategies After Cryptogenic Stroke (from the Cryptogenic Stroke and Underlying AF Trial)
Ischemic stroke cause remains undetermined in 30% of cases, leading to a diagnosis of cryptogenic stroke. Paroxysmal atrial fibrillation (AF) is a major cause of ischemic stroke but may go undetected with short periods of ECG monitoring. The Cryptogenic Stroke and Underlying Atrial Fibrillation trial (CRYSTAL AF) demonstrated that long-term electrocardiographic monitoring with insertable cardiac monitors (ICM) is superior to conventional follow-up in detecting AF in the population with cryptogenic stroke.
Source: The American Journal of Cardiology - June 24, 2015 Category: Cardiology Authors: William C. Choe, Rod S. Passman, Johannes Brachmann, Carlos A. Morillo, Tommaso Sanna, Richard A. Bernstein, Vincenzo Di Lazzaro, Hans-Christoph Diener, Marilyn M. Rymer, Frank Beckers, Jodi Koehler, Paul D. Ziegler, CRYSTAL AF Investigators Tags: Arrhythmias and Conduction Disturbances Source Type: research

Association Between High-Sensitivity C-Reactive Protein and Total Stroke by Hypertensive Status Among Men Arrhythmia and Electrophysiology
Conclusions Elevated hsCRP levels were associated with a greater risk of total stroke, even after adjustment for potential confounders and cardiovascular risk factors. Risk of total stroke was significantly higher among hypertensive men with elevated hsCRP compared with normotensive men with low hsCRP.
Source: JAHA:Journal of the American Heart Association - September 21, 2015 Category: Cardiology Authors: Jimenez, M. C., Rexrode, K. M., Glynn, R. J., Ridker, P. M., Gaziano, J. M., Sesso, H. D. Tags: Arrhythmia and Electrophysiology Source Type: research

Clinical and pathogenic features of ischemic stroke among representatives of different gender and age groups
Abstract A total of 1410 patients with ischemic stroke (IS) of four main clinical and pathogenic subtypes, viz., atherothrombotic, cardioembolic, hemodynamic, and lacunar strokes, were studied. We analyzed the dependence of the pathogenic subtype of the stroke, its background pathologies, and stroke risk factors on the age and gender of the patients. It was found that senior patients were more susceptible to atherothrombotic ischemic strokes and patients of working age more frequently suffered from lacunar and hemodynamic strokes, although cases of atherothrombotic strokes in this age cohort were more often obser...
Source: Advances in Gerontology - December 31, 2015 Category: Geriatrics Source Type: research

An evidence-based review of edoxaban and its role in stroke prevention in patients with nonvalvular atrial fibrillation
Tushar Acharya, Prakash Deedwania Division of Cardiology, Department of Internal Medicine, University of California, San Francisco, Fresno, CA, USA Abstract: Atrial fibrillation is the most common arrhythmia in the elderly. It is responsible for significant morbidity and mortality from cardioembolic complications like stroke. As a result, atrial fibrillation patients are risk-stratified using the CHADS2 or CHA2DS2-VASc scoring systems. Those at intermediate-to-high risk have traditionally been treated with therapeutic anticoagulation with warfarin for stroke prevention. Although effective, warfarin use is fraught with mult...
Source: Core Evidence - April 27, 2015 Category: Drugs & Pharmacology Tags: Core Evidence Source Type: research

Long-term Arrhythmia Monitoring in Cryptogenic Stroke: Who, How, and for How Long?
Authors: Montalvo M, Ali R, Silver B, Khan M Abstract Cryptogenic stroke and transient ischemic attack (TIA) account for approximately one-third of stroke patients [1]. Paroxys-mal atrial fibrillation (PAF) has been suggested as a major etiology of these cryptogenic strokes [2, 3]. PAF can be difficult to diagnose because it is intermittent, often brief, and asymptomatic. PAF might be more prevalent than persistent atrial fibrillation in stroke and TIA patients, especially in younger populations [4, 5]. In patients with atrial fibrillation, anticoagulation provides significant risk reduction [6]. A new generation o...
Source: Open Cardiovascular Medicine Journal - June 29, 2016 Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research

Stroke Prediction in Atrial Fibrillation Is it Black and White? ∗
Atrial fibrillation (AF) is a common arrhythmia that predisposes patients to risk of stroke (1) that can be prevented with anticoagulation (2) . However, a minority of patients with AF and risk of stroke are treated with anticoagulants (3) , with undertreatment being due to a variety of factors. Optimizing treatment depends, in part, on the ability to understand risks, benefits, and personal preferences of individual patients. The CHADS 2 (congestive heart failure, hypertension, age  ≥75 years, diabetes, and 2 points for prior stroke or transient ischemic attack) scoring system has been useful for stratifying risk of ...
Source: Journal of the American College of Cardiology - July 26, 2016 Category: Cardiology Source Type: research

E-004 Factors Associated with Successful Revascularization using the Aspiration Component of ADAPT in the Treatment of Acute Ischemic Stroke
ConclusionsAspiration success was associated with younger age. There was a trend for aspiration failure to be associated with cardiogenic etiology and more difficult vascular anatomy. Our findings suggest that the ADAPT technique can be used for the vast majority of patients but it may be beneficial to use a SR primarily when performing thrombectomy in the elderly. Further research analyzing thrombus characteristics is needed.References1 Turk AS, Frei D, Fiorella D, et al. ADAPT FAST study: a direct aspiration first pass technique for acute stroke thrombectomy. J Neurointerv Surg 2014 ;6(4):260–4.2 Turk AS, Turner R,...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Mascitelli, J., Kellner, C., Oravec, C., DeLeacy, R., Oermann, E., Paramasivam, S., Fifi, J., Mocco, J. Tags: Electronic poster abstracts Source Type: research

Pivotal trial pits St. Jude Medical ’ s Amplatzer Amulet anti-stroke device against Boston Scientific ’ s Watchman
St. Jude Medical (NYSE:STJ) said today that it launched a U.S. pivotal trial for its Amplatzer Amulet cardiac implant, which is designed to reduce the risk of stroke in patients with atrial fibrillation. The Amplatzer Amulet device is designed to occlude the left atrial appendage to prevent the formation of blood clots that could lead to a stroke. The FDA approved a similar device made by Boston Scientific (NYSE:BSX), the Watchman implant, in March 2015; St. Jude’s 1,600-patient IDE trial will compare the Amplatzer Amulet to the Watchman in patients with non-ventricular arrhythmias. The primary safety endpoint is ...
Source: Mass Device - September 1, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiac Implants Cardiovascular Clinical Trials Wall Street Beat Boston Scientific St. Jude Medical Source Type: news