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Total 207 results found since Jan 2013.
Therapeutic benefits of prophetic medicine remedies in treating hematological diseases (A review article)
Am J Blood Res. 2023 Aug 15;13(4):130-142. eCollection 2023.ABSTRACTHematological disorders are common medical ailments constituting an important cause of morbidity and mortality worldwide, which may be managed efficiently using different prophetic medicine remedies as adjuvants to current therapeutics. Prophetic medicine includes the body of knowledge about medicine that has been derived from the deeds, customs (sunnah), ahadith (sayings), actions, and agreements of Prophet Muhammad, peace be upon him. This review article aims at exploring the magnitude of therapeutic benefits of prophetic medicine remedies as adjuvant tr...
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Ghazi H Mogharbel Ahmad S Badawi Amal Yaseen Zaman Mehrevan M Abd Elmoniem Ibrahim M Abdel-Rahman Mariam Eid Alenazi Fareed Akbar Shah Mohamed Abdelnaem Aly Syed Nazar Imam Nusaybah Eid Alenazi Salah Mohamed El Sayed Source Type: research
Macrophage ferroptosis promotes MMP2/9 overexpression induced by hemin in hemorrhagic plaque
Conclusions Our results suggested that hemin-induced macrophage ferroptosis promotes p38 pathway activation and MMP2/9 overexpression, which may play a crucial role in increasing hemorrhagic plaque vulnerability. These findings provide insights into the pathogenesis of hemorrhagic plaques and suggest that targeting macrophage ferroptosis may be a promising strategy for stabilizing vulnerable plaque.PMID:37696298 | DOI:10.1055/a-2173-3602
Source: Thrombosis and Haemostasis - September 11, 2023 Category: Hematology Authors: Bicheng Li Minqiao Lu Hui Wang Siqi Sheng Shuyuan Guo Jia Li Ye Tian Source Type: research
Transcriptomic Profiling Identifies Ferroptosis-Related Gene Signatures in Ischemic Muscle Satellite Cells Affected by Peripheral Artery Disease
CONCLUSIONS: This is the first report documenting that genes known to be involved in ferroptosis are differentially expressed in human skeletal muscle affected by PAD. Targeting ferroptosis may be a novel therapeutic strategy to reduce PAD myopathy.PMID:37675635 | DOI:10.1161/ATVBAHA.123.319518
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 7, 2023 Category: Cardiology Authors: Lillian Tran Bowen Xie Edwyn Assaf Ricardo Ferrari Iraklis I Pipinos George P Casale Roberto Ivan Mota Alvidrez Simon Watkins Ulka Sachdev Source Type: research
Improving the Performance of Poly(caprolactone)-Cellulose Acetate-Tannic Acid Tubular Scaffolds by Mussel-Inspired Coating
In this study, tubular scaffolds consisting of a composite of poly(caprolactone), cellulose acetate, and tannic acid (TA) were electrospun, and then the scaffolds were treated with different Fe(III) solutions (iron(III) chloride hexahydrate (FeCl3'6H2O)) to obtain four tubular scaffolds: F0, F5, F15, and F45. According to scanning electron microscopy (SEM) and field emission-SEM results, TA/Fe(III) complex is coated on the fiber of the scaffold after post-treatment; the fiber surface morphology changes with different Fe(III) concentrations. This provides designability to the performance of tubular scaffolds. The tensile st...
Source: Biomacromolecules - August 28, 2023 Category: Biochemistry Authors: Hao Wang Hong Xia Wendan Yang Zhenzhen Xu Toshiaki Natsuki Qing-Qing Ni Source Type: research
Prevalence and Risk Factors for Bleeding in Hereditary Hemorrhagic Telangiectasia: A National Inpatient Sample Study
In conclusion, AVM and angiodysplasia are more common, and HMB and PPH less common in HHT than non-HHT. Iron deficiency anemia prevalence is similar in bleeders and non-bleeders, suggesting ongoing blood loss and need for universal iron screening.PMID:37567149 | DOI:10.1182/bloodadvances.2023010743
Source: Adv Data - August 11, 2023 Category: Epidemiology Authors: Jabra Zarka Kwonho Jeong Jonathan G Yabes Margaret V Ragni Source Type: research
Ferrozoles: Ferrocenyl derivatives of letrozole with dual effects as potent aromatase inhibitors and cytostatic agents
J Biol Inorg Chem. 2023 Jul 17. doi: 10.1007/s00775-023-02006-0. Online ahead of print.ABSTRACTIn the treatment of hormone-dependent cancers, aromatase inhibitors (AI) are receiving increased attention due to some undesirable effects such as the risk of endometrial cancer and thromboembolism of SERMs (selective estrogen receptor modulators). Letrozole is the most active AI with 99% aromatase inhibition. Unfortunately, this compound also exhibits some adverse effects such as hot flashes and fibromyalgias. Therefore, there is an urgent need to explore new types of AIs that retain the same-or even increased-antitumor ability....
Source: Journal of Biological Inorganic Chemistry : JBIC - July 17, 2023 Category: Chemistry Authors: Borja Diaz de Gre ñu Diego M Fern ández-Aroca Juan A Organero Gema Dur á Felix Angel Jal ón Ricardo S ánchez-Prieto M Jos é Ruiz-Hidalgo Ana Mar ía Rodríguez Lucia Santos Jos é L Albasanz Blanca R Manzano Source Type: research
The "Viral" Form of Polyarteritis Nodosa (PAN)-A Distinct Entity: A Case Based Review
Conclusions: The viral form of PAN seems to be individualized as a distinct entity, requiring early, aggressive medication.PMID:37374366 | PMC:PMC10305326 | DOI:10.3390/medicina59061162
Source: Medicina (Kaunas) - June 28, 2023 Category: Universities & Medical Training Authors: Victoria Pa șa Elena Popa Mihaela Poroch Adriana Cosmescu Agnes Iacinta Bacusca Ana Maria Slanina Alexandr Ceasovschih Alexandra Stoica Antoneta Petroaie Monica Ungureanu Andrei Emilian Popa Raluca Ioana Avram Cristina Bologa Vladimir Poroch Elena Adorat Source Type: research
