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Condition: Thrombosis
Procedure: Blood Transusion

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Total 82 results found since Jan 2013.

Short-term Medical Complications Following Short Versus Long Cephalomedullary Nails.
Abstract The purpose of this retrospective cohort study was to evaluate whether there is an increased rate of short-term medical complications following short vs long cephalomedullary nails for the treatment of intertrochanteric hip fractures. A total of 899 patients treated surgically with cephalomedullary nails from January 1, 2005, to September 1, 2014, were included. Patients who received short nails (n=334) were older and had a higher incidence of coronary artery disease and diabetes mellitus compared with patients who received long nails (n=565). The incidences of 30-day medical complications, including myoc...
Source: Orthopedics - July 16, 2018 Category: Orthopaedics Authors: Liu J, Frisch NB, Mehran N, Qatu M, Guthrie ST Tags: Orthopedics Source Type: research

To Pack or Not to Pack: Inpatient Management of Epistaxis in the Elderly.
Conclusion Nonpacking interventions in the elderly do not appear to be associated with increased morbidity or mortality when compared to nasal packing only but appear to be associated with increased hospital charges and length of stay. Embolization in the elderly results in greater hospital charges but no change in outcome when compared to ligation. PMID: 30270635 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - October 1, 2018 Category: ENT & OMF Authors: Zhou AH, Chung SY, Sylvester MJ, Zaki M, Svider PS, Hsueh WD, Baredes S, Eloy JA Tags: Am J Rhinol Allergy Source Type: research

Unicompartmental knee replacement – An underrated alternative of total knee replacement: A matched comparative study analysing their benefits and risks in local population
ConclusionBecause of less operative risk and faster rehabilitation, this study suggested that unicompartmental knee replacement is more cost effective and might be a better choice for patients with unicompartmental arthritis in local population.中文摘要簡介膝關節置換術的需求跟隨全世界人口老齡化不斷增加。儘管單室膝關節置換術有較少並發症，即中風﹑心肌梗死﹑血栓栓塞﹑輸血和死亡率，它僅佔所有膝關節置換術的 3一8％，這項研究的目標是比較在香港人口的單室膝關節置換術與全膝關節置換術，通過評估的好處和風險...
Source: Journal of Orthopaedics, Trauma and Rehabilitation - October 16, 2018 Category: Orthopaedics Source Type: research

Emicizumab for the Treatment of Acquired Hemophilia_A: Lessons Learned from 4 Very Different Cases
In conclusion, emiczumab seems to be an effective hemostatic therapy also for AHA, which offers several advantages: subcutaneous weekly therapy, good hemostatic efficacy, possible outpatient therapy, the option to reduce the intensity of immunosuppressive therapy to avoid side effects (as the patients are protected from bleeding), and seems even to be more cost effective than bypassing agents. However, special attention is necessary on the use of appropriate lab assays (chromogenic FVIII assays), the artificial effects on APTT and Bethesda assays, the recognition of the remission, and to avoid the concomitant use of APCC. ...
Source: Blood - November 21, 2018 Category: Hematology Authors: Knoebl, P., Sperr, W. R., Schellongowski, P., Staudinger, T., Jilma-Stohlawetz, P., Quehenberger, P., Koder, S., Ay, C., Gleixner, K. V. Tags: 322. Disorders of Coagulation or Fibrinolysis: Poster II Source Type: research

Major cardiovascular and bleeding events with long-term use of aspirin in patients with prior cardiovascular diseases: 1-year follow-up results from the Management of Aspirin-induced Gastrointestinal Complications (MAGIC) study
This study was conducted to clarify CV and bleeding events in Japanese aspirin users with a history of CV diseases. This study was a prospective, nationwide, multicenter cooperative registry of Japanese patients with CV diseases at risk of thromboembolism who were taking aspirin (75–325 mg) for at least 1 year. We observed major CV and bleeding events during follow-up. Patients with history of ischemic stroke (IS), transient ischemic attack (TIA), coronary artery disease (CAD), atrial fibrillation (AF), and venous thromboembolism (VTE) were included and analyzed in this sutdy. CV events included IS, TIA, CAD, CV death,...
Source: Heart and Vessels - August 23, 2019 Category: Cardiology Source Type: research

Outcome impact of different tranexamic acid regimens in cardiac surgery with cardiopulmonary bypass (OPTIMAL): Rationale, design, and study protocol of a multi-center randomized controlled trial
ConclusionsThe study is designed to identify a TxA dose with maximal efficacy and minimal complications. We hypothesize that the high dose has superior efficacy and non-inferior safety to the low dose.
Source: American Heart Journal - October 22, 2019 Category: Cardiology Source Type: research

Cerebral sinovenous thrombosis in a child with ulcerative colitis: A case report
Rationale: Cerebral sinovenous thrombosis (CVT) associated with inflammatory bowel disease (IBD) is infrequent, but clinically nonnegligible due to its high disability and fatality rates. Patient concerns: A 12-year-old child with newly developed ulcerative colitis (UC) suffered from a sudden left-sided hemiparesis and numbness. Diagnoses: Cerebral sinovenous thrombosis due to ulcerative colitis was diagnosed in this girl. Interventions: The patient was treated with blood transfusion and anticoagulation therapy. Digital subtraction angiography (DSA) and urokinase thrombolysis were implemented followed. Outcomes...
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Intravenous Fat Emulsion Does Not Significantly Alter Clotting Markers in Dabigatran-Treated Blood
AbstractDabigatran etexilate is an oral direct thrombin (Factor IIa) inhibitor approved for patients with atrial fibrillation and for management of risk of deep vein thrombosis and pulmonary embolism. Dabigatran offers advantages over treatment with warfarin, including limited laboratory monitoring. It is equivalent in prevention of stroke and deep vein thrombosis with essentially equivalent complication rates. In contrast to warfarin, reversal of the anticoagulation is less well established. Idarucizumab is available for reversal, however supporting research is mixed; the agent also happens to be quite expensive making av...
Source: Indian Journal of Hematology and Blood Transfusion - June 21, 2020 Category: Hematology Source Type: research

Viable Hemostasis Obtained With Prothrombin Complex Concentrate in Patients Who Refuse Standard Allogeneic Blood Transfusion and Undergo Complex Cardiac Surgery: A Case Series
Human 4-factor prothrombin complex concentrate (4F-PCC) may reduce blood loss during surgery. This case series described perioperative outcomes among 9 patients who refused standard allogeneic blood transfusion, underwent complex cardiac surgery with aortic involvement, and received intraoperative 4F-PCC. Additional intraoperative cointerventions included protamine (n = 9), aminocaproic acid (n = 8), fibrinogen concentrate (n = 6), desmopressin (n = 6), factor VIIa (n = 2), and tranexamic acid (n = 1). Outcomes included postoperative death (n = 1), major postoperative bleeding (n = 1), deep vein thrombosis (n = 2), and isc...
Source: A&A Case Reports - July 1, 2020 Category: Anesthesiology Tags: Case Series Source Type: research

Mortality and Morbidity of Surgical Management of Geriatric Ankle Fractures.
DISCUSSION: After controlling for comorbidities (ie, the ASA class), no increased risk is observed for the 30-day mortality or complication rate between geriatric ankle fracture in the 65 to 79 years old and the 80 to 99 years old age groups. LEVEL OF EVIDENCE: Prognostic level III, retrospective study. PMID: 32769723 [PubMed - in process]
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 13, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Trends in Comorbidities and Complications Among Patients Undergoing Inpatient Spine Surgery
Study Design. Retrospective database study. Objective. We sought to identify trends in demographics, comorbidities, and postoperative complications among patients undergoing ACDF and PLF. Summary of Background Data. As demand for anterior cervical discectomy and fusion (ACDF) and posterior lumbar fusion (PLF) surgery continues to increase, it is important to understand changes in the healthcare system and patient populations undergoing these procedures. Methods. We identified 220,520 ACDF and 151,547 PLF surgeries (2006–2016; Premier Healthcare database). Annual proportions or medians were calculated for patie...
Source: Spine - August 28, 2020 Category: Orthopaedics Tags: SURGERY Source Type: research

Intra-and postoperative complications in the treatment of spinal metastases. A multicentre surveillance study from the German Spinal Registry (DWG-Register).
CONCLUSIONS: This analysis provides predictive models for surgeons to identify patients who may benefit from transitional care programmes. Preoperative status, invasiveness, blood loss> 500 ml and blood transfusions are independent predictors associated with higher risk of complication. PMID: 33047579 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgical Sciences - October 15, 2020 Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research

Preoperative anemia and complications after surgery for pelvic organ prolapse: an analysis of the national surgical quality improvement program database
ConclusionsPreoperative anemia is associated with an increased risk of adverse postoperative outcomes in women having surgery for pelvic organ prolapse.
Source: International Urogynecology Journal - April 24, 2021 Category: OBGYN Source Type: research

Vascular procedures in patients with left ventricular assist devices: single-center experience
ConclusionPatients on LVAD support are a complex cohort with a high risk for perioperative complications. In a setting where device function and anticoagulation are monitored closely, vascular surgery in these patients is feasible with an acceptable perioperative risk.
Source: Indian Journal of Thoracic and Cardiovascular Surgery - May 27, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

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