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Specialty: Cardiology
Condition: Thrombosis
Education: Study

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Total 1905 results found since Jan 2013.

Pulmonary Embolism in Ischemic Stroke: Clinical Presentation, Risk Factors, and Outcome Stroke
Conclusions In this large cohort study, PE occurred in nearly 1% of AIS patients. PE was more common in patients with severe stroke, history of cancer, previous DVT/PE or acute DVT and associated with lower short- and long-term survival, greater disability, and longer length of stay.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Pongmoragot, J., Rabinstein, A. A., Nilanont, Y., Swartz, R. H., Zhou, L., Saposnik, G., The Investigators of the Registry of the Canadian Stroke Network (RCSN) and University of Toronto Stroke Program for the Stroke Outcomes Research Canada (SORCan [www. Tags: Stroke Source Type: research

The predictive role of CHA2DS2–VASc score between venous thromboembolism and ischemic stroke: a large-scale cohort study
Conclusion: Our study is the first to concern the performance of CHA2DS2–VASc score in predicting the risk of ischemic stroke in VTE patients and the risk of VTE in ischemic stroke patients. Nevertheless, the performance of the score was modest, and the transportability of the score in these populations still needs to be defined.
Source: Journal of Hypertension - February 2, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Racial-Ethnic Disparities in Acute Stroke Care in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study Epidemiology
We examined race‐ethnic disparities in acute stroke performance metrics in a voluntary stroke registry among Florida and Puerto Rico Get With the Guidelines‐Stroke hospitals.Methods and ResultsSeventy‐five sites in the Florida Puerto Rico Stroke Registry (66 Florida and 9 Puerto Rico) recorded 58 864 ischemic stroke cases (2010–2014). Logistic regression models examined racial‐ethnic differences in acute stroke performance measures and defect‐free care (intravenous tissue plasminogen activator treatment, in‐hospital antithrombotic therapy, deep vein thrombosis prophylaxis, discharge antithrombotic therapy, a...
Source: JAHA:Journal of the American Heart Association - February 14, 2017 Category: Cardiology Authors: Sacco, R. L., Gardener, H., Wang, K., Dong, C., Ciliberti-Vargas, M. A., Gutierrez, C. M., Asdaghi, N., Burgin, W. S., Carrasquillo, O., Garcia-Rivera, E. J., Nobo, U., Oluwole, S., Rose, D. Z., Waters, M. F., Zevallos, J. C., Robichaux, M., Waddy, S. P., Tags: Epidemiology, Race and Ethnicity, Treatment, Cerebrovascular Disease/Stroke Original Research Source Type: research

Ischemic Stroke and Risk of Venous Thromboembolism in the General Population: The Tromso Study Epidemiology
ConclusionsThe risk of VTE increased during the first 3 months after an ischemic stroke. The particularly high risk of provoked VTE suggests that additional predisposing factors, such as immobilization, potentiate the VTE risk in patients with ischemic stroke.
Source: JAHA:Journal of the American Heart Association - November 6, 2016 Category: Cardiology Authors: Rinde, L. B., Smabrekke, B., Mathiesen, E. B., Lochen, M.–L., Nȷolstad, I., Hald, E. M., Wilsgaard, T., Brakkan, S. K., Hansen, J.–B. Tags: Epidemiology, Risk Factors, Ischemic Stroke, Thrombosis Original Research Source Type: research

Paradoxical Association of Smoking With In-Hospital Mortality Among Patients Admitted With Acute Ischemic Stroke Stroke
Conclusions Similar to myocardial ischemia, smoking was independently associated with lower inpatient mortality in acute ischemic stroke. This effect may be due to tobacco-induced changes in cerebrovascular vasoreactivity, or may be due in part to residual confounding. Larger, multicenter studies are needed to confirm the finding and the effect on 30-day and 1-year mortality.
Source: JAHA:Journal of the American Heart Association - June 19, 2013 Category: Cardiology Authors: Ali, S. F., Smith, E. E., Bhatt, D. L., Fonarow, G. C., Schwamm, L. H. Tags: Stroke Source Type: research

Causes of ischemic stroke in young adults versus non-young adults: A multicenter hospital-based observational study
CONCLUSIONS: Certain embolic sources and uncommon causes may be etiologically important causes of ischemic stroke in young adults. However, the contribution of conventional vascular risk factors and lifestyle-related risk factors is not negligible with advancing age, even in young adults.PMID:35830430 | DOI:10.1371/journal.pone.0268481
Source: Atherosclerosis - July 13, 2022 Category: Cardiology Authors: Yuichiro Ohya Ryu Matsuo Noriko Sato Fumi Irie Kuniyuki Nakamura Yoshinobu Wakisaka Tetsuro Ago Masahiro Kamouchi Takanari Kitazono Investigators for Fukuoka Stroke Registry Source Type: research

Comparative Effectiveness of Interventions for Stroke Prevention in Atrial Fibrillation: A Network Meta-Analysis Arrhythmia and Electrophysiology
Conclusions The entire spectrum of therapy to prevent thromboembolism in nonvalvular AF significantly reduced stroke/systemic embolism events and mortality.
Source: JAHA:Journal of the American Heart Association - May 19, 2016 Category: Cardiology Authors: Tereshchenko, L. G., Henrikson, C. A., Cigarroa, J., Steinberg, J. S. Tags: Atrial Fibrillation, Anticoagulants, Treatment, Meta Analysis, Cerebrovascular Disease/Stroke Arrhythmia and Electrophysiology Source Type: research

Rare Variants in the ADAMTS13 Von Willebrand Factor-Binding Domain Contribute to Pediatric Stroke Original Articles
Conclusions— Our data provide a link between the genetic architecture of ADAMTS13, ADAMTS13 levels, and stroke susceptibility. Altogether, these studies render ADAMTS13 an attractive candidate for functional studies and may contribute to personalized diagnosis and treatment options in future.
Source: Circulation: Cardiovascular Genetics - August 15, 2016 Category: Cardiology Authors: Stoll, M., Ruhle, F., Witten, A., Barysenka, A., Arning, A., Strauss, C., Nowak-Gottl, U. Tags: Cardiovascular Disease, Genetic, Association Studies, Ischemic Stroke, Thrombosis Original Articles Source Type: research

Impact of angiotensin-converting enzyme inhibition on platelet tissue factor expression in stroke-prone rats
Conclusion: The current study shows for the first time that in hypertension the number of TF-positive megakaryocytes increases thus releasing in the circulation more platelets carrying a functionally active TF. AngII stimulates platelets to express TF.
Source: Journal of Hypertension - May 1, 2018 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Pravastatin Reduces the Risk of Atherothrombotic Stroke when Administered within Six Months of an Initial Stroke Event.
CONCLUSIONS: Pravastatin is likely to reduce atherothrombotic stroke in patients enrolled within 6 months after stroke onset. However, the clinical efficacy for prevention of recurrent stroke was not conclusive with earlier statin treatment. PMID: 28924103 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 20, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Cryptogenic Stroke: Diagnostic Workup and Management
AbstractPurpose of reviewCryptogenic stroke describes a subset of ischemic stroke for which no cause can be found despite a structured investigation. There are a number of putative mechanisms of cryptogenic ischemic stroke including a covert structural cardiac lesion, paroxysmal atrial fibrillation, hypercoagulable state or undiagnosed malignancy. Because many of these proposed mechanisms are embolic – and based on studies of thrombus history showing commonalities between thrombus composition between cardioembolic and cryptogenic strokes – the concept of embolic stroke of undetermined source (ESUS) (Hart et al. Lancet ...
Source: Current Treatment Options in Cardiovascular Medicine - December 2, 2019 Category: Cardiology Source Type: research

Japanese and Non-Japanese Patients with Transient Ischemic Attack or Minor Stroke: A Five-Year Risk Analysis of Stroke and Vascular Events.
CONCLUSIONS: Recurrent stroke and intracranial hemorrhage were determined to be more prevalent at 5 years after TIA or minor stroke in Japanese patients than in non-Japanese patients. Strategies to mitigate the long-term risks of stroke, aside from adherence to current guidelines, should take Japanese-patient-specific residual risks into account. PMID: 32938836 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 19, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study.
CONCLUSIONS: Higher levels of sLOX-1 were observed in patients with acute stoke than in controls. High levels of sLOX-1 can be useful as biomarker for acute stroke. PMID: 27025681 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - March 31, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Atrial fibrillation and risk of stroke: a nationwide cohort study
Conclusions Stroke/TE/TIA risk was particularly increased when prior stroke/TE/TIA was present. Atrial fibrillation is associated with an increase in risk of stroke/TE/TIA in the absence of other risk factors but only a moderate increase in risk when other risk factors are present.
Source: Europace - November 1, 2016 Category: Cardiology Authors: Christiansen, C. B., Gerds, T. A., Olesen, J. B., Kristensen, S. L., Lamberts, M., Lip, G. Y. H., Gislason, G. H., Kober, L., Torp-Pedersen, C. Tags: Atrial fibrillation Source Type: research