Rare Variants in the ADAMTS13 Von Willebrand Factor-Binding Domain Contribute to Pediatric Stroke [Original Articles]

Conclusions— Our data provide a link between the genetic architecture of ADAMTS13, ADAMTS13 levels, and stroke susceptibility. Altogether, these studies render ADAMTS13 an attractive candidate for functional studies and may contribute to personalized diagnosis and treatment options in future.
Source: Circulation: Cardiovascular Genetics - Category: Cardiology Authors: Tags: Cardiovascular Disease, Genetic, Association Studies, Ischemic Stroke, Thrombosis Original Articles Source Type: research