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Nutrition: Weight Loss

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Total 615 results found since Jan 2013.

Guideline: ACP recommends weight loss and CPAP therapy for obstructive sleep apnea
People diagnosed with obstructive sleep apnea (OSA) should not consider surgery, according to new recommendations from the American College of Physicians (ACP). Instead, ACP recommends that patients lose weight and use continuous positive airway pressure (CPAP) as initial therapy. More than 18 million American adults have sleep apnea, which increases the risk of high blood pressure, heart attack, stroke, heart failure, and diabetes and increases the chance of driving or other accidents. Sleep apnea is a leading cause of excessive daytime sleepiness...
Source: Health News from Medical News Today - September 25, 2013 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes
In this study, conducted in 16 centers in the United States, 5145 overweight or obese patients with type 2 diabetes were randomly assigned to participate in an intensive lifestyle intervention that promoted weight loss through decreased caloric intake and increased physical activity, the intervention group, or receive diabetes support and education only, the control group. The primary outcome was a composite of death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for angina occurring over a maximum follow-up of 13.5 years. At a median follow-up of 9.6 years, the trial was st...
Source: Journal of Vascular Surgery - October 1, 2013 Category: Surgery Authors: The Look AHEAD Research Group Tags: Abstracts Source Type: research

A case report of adult lead toxicity following use of Ayurvedic herbal medication
DiscussionA high index of suspicion of metal toxicity is necessary among persons with characteristic symptoms and signs in the absence of occupational exposure. Despite limited evidence for chelation in adults and in those with modest blood lead levels, this patient appeared to benefit from repeated chelation therapy. Both allopathic and alternative medicine practitioners and public health specialists need to be aware of the potential for contamination of and side effects from alternative pharmacologic and herbal therapies.
Source: Journal of Occupational Medicine and Toxicology - October 2, 2013 Category: Occupational Health Authors: Laura BreeherFred GerrLaurence Fuortes Source Type: research

Could leptin explain the link between abdominal obesity and cardiovascular disease
High levels of adipose tissue hormone leptin in the blood reduces blood vessels' ability to dilate, and also affects blood clotting, all of which increase the risk of heart attack and stroke. These are some of the results that Manuel Gonzalez shows in his doctoral thesis that he defended at Umea University. Numerous population studies have shown that overweight people, especially those with abdominal obesity, have a higher risk of coronary artery disease and myocardial infarction...
Source: Health News from Medical News Today - October 9, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Correlates of ADL difficulty in a large hemodialysis cohort
Abstract Needing assistance with activities of daily living (ADL) is an early indicator of functional decline and has important implications for individuals' quality of life. However, correlates of need for ADL assistance have received limited attention among patients undergoing maintenance hemodialysis (HD). A multicenter cohort of 742 prevalent HD patients was assessed in 2009–2011 and classified as frail, prefrail and nonfrail by the Fried frailty index (recent unintentional weight loss, reported exhaustion, low grip strength, slow walk speed, low physical activity). Patients reported need for assistance with 4 ADL ta...
Source: Hemodialysis International - October 9, 2013 Category: Hematology Authors: Nancy G. Kutner, Rebecca Zhang, Richard M. Allman, C. Barrett Bowling Tags: Original Article Source Type: research

Kidney Function and Prevalent and Incident Frailty.
CONCLUSIONS: In community-dwelling elders, lower eGFRcys was associated with a higher risk of prevalent and incident frailty whereas lower eGFRSCr was not. These findings highlight the importance of considering non-GFR determinants of kidney function. PMID: 24178972 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - October 31, 2013 Category: Urology & Nephrology Authors: Dalrymple LS, Katz R, Rifkin DE, Siscovick D, Newman AB, Fried LF, Sarnak MJ, Odden MC, Shlipak MG Tags: Clin J Am Soc Nephrol Source Type: research

Improved sex drive after bariatric surgery
The health risks of obesity are well known, with increased risk of cardiovascular diseases, type 2 diabetes, stroke and certain cancers. But what is not so well known is how it affects women's sex drive and satisfaction, something researchers from the University of Pennsylvania set out to explore. In a study, published in JAMA Surgery this month, Prof. David B. Sarwer, of the University's Perelman School of Medicine, and colleagues conducted a study with women who underwent bariatric surgery...
Source: Health News from Medical News Today - November 5, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Menopause and Weight Gain
Many women approaching the menopause will experience a number of symptoms, including vaginal dryness, hot flushes and a lack of sex drive. However another symptom that may arise as a result of the menopause is weight gain. Most commonly occurring around the hips and abdomen, this menopausal symptom for the majority of women is considered to be the least desirable. Photo: Nikodem Nijaki: Wikipedia Although the exact factors that contribute to weight gain are not entirely understood, it is known that a decline in oestrogen levels, a loss of muscle tissue and lifestyle factors are part of the cause. Though it can be argued t...
Source: The Hysterectomy Association - November 7, 2013 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: menopause hormone replacement therapy oestrogen weight gain Source Type: news

New heart guidelines back stronger therapies for high risk patients
(Reuters) - New U.S. guidelines on heart health that were a decade in the making recommend stronger measures for patients at particularly high risk of heart attack or stroke, including more aggressive therapy with drugs that lower cholesterol or even bariatric weight loss surgery.
Source: Reuters: Health - November 12, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

New U.S. heart guidelines back stronger therapies for high-risk patients
(Reuters) - New U.S. guidelines on heart health that were a decade in the making recommend stronger measures for patients at particularly high risk of heart attack or stroke, including more aggressive therapy with drugs that lower cholesterol or even weight loss surgery.
Source: Reuters: Health - November 12, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

The extra‐pancreatic effects of GLP‐1 receptor agonists: a focus on the cardiovascular, gastrointestinal and central nervous systems
Abstract The glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) exenatide and liraglutide have been shown to improve glycaemic control and beta‐cell function with a low risk of hypoglycaemia in people with type 2 diabetes. GLP‐1 receptors are also expressed in extra‐pancreatic tissues and trial data suggest GLP‐1RAs also have effects beyond their glycaemic actions. Preclinical studies using native GLP‐1 or GLP‐1RAs provide substantial evidence for cardioprotective effects, while clinical trial data have demonstrated beneficial actions on hypertension and dyslipidaemia in people with type 2 diabetes. Sig...
Source: Diabetes, Obesity and Metabolism - December 24, 2013 Category: Endocrinology Authors: J Seufert, B Gallwitz Tags: Unsolicited Review Article Source Type: research

No pain, no gain? Getting the most out of exercise
Staying in shape has all sorts of benefits, from maintaining heart health to warding off dementia and cancerInactivity – fuelled by cars and a sedentary work life – has been dubbed the biggest public health problem of the 21st century, a global pandemic with dramatic impact on peoples wellbeing. The latest reports suggest that around the world it was responsible for 5.3 million deaths in 2008 – around one in 10 – more deaths than smoking.Not only does exercise make you fitter, it can also ward off numerous and often unexpected diseases, from heart attacks, to diabetes, some forms of cancer and dementia. There are t...
Source: Guardian Unlimited Science - January 13, 2014 Category: Science Authors: Catherine de Lange Tags: Cycling Fitness Sport Running Transport Yoga Weightlifting Features UK news Life and style Cycle hire schemes The Observer Swimming Science Source Type: news

A safe, effective diet pill - the elusive holy grail
Trade in illegal, ineffective drugs flourishes as pharmaceutical industry repeatedly fails to produce successful pillAttempts to invent a safe and effective diet pill have foundered time and again, allowing the internet trade in illegal and ineffective herbal supplements and dangerous drugs, such as DNP, to flourish.A successful diet pill could make billions for the pharmaceutical industry, but efforts to date have ended in disaster, with patients harmed, drugs banned and massive compensation paid out.Fen-phen, an appetite suppressant, was the most spectacular failure. It was withdrawn in the US in 1997 after causing wides...
Source: Guardian Unlimited Science - January 14, 2014 Category: Science Authors: Sarah Boseley Tags: The Guardian Diets and dieting Drugs trade Healthcare industry World news Pharmaceuticals industry & wellbeing Health policy Society Politics UK news Life and style Public services policy Business Science Source Type: news

Inhibition of Transforming Growth Factor-{beta} Attenuates Brain Injury and Neurological Deficits in a Rat Model of Germinal Matrix Hemorrhage Basic Sciences
Conclusions— Increased level of TGF-β1 and activation of the TGF-β pathway associate with the development of brain injury after GMH. SD208 inhibits GMH-induced activation of the TGF-β pathway and leads to an improved developmental profile, partial recovery of cognitive and motor functions, and attenuation of GMH-induced brain atrophy and hydrocephalus.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Manaenko, A., Lekic, T., Barnhart, M., Hartman, R., Zhang, J. H. Tags: Animal models of human disease, Neuroprotectors Basic Sciences Source Type: research

Obese kids: inadequate sleep may increase heart disease risk
Telling adolescents to get enough sleep can sometimes be a tall order, but a new study in The Journal of Pediatrics reminds us just how important a good night's sleep can be. It suggests obese youths who do not get adequate sleep may increase their risk for developing diabetes, heart disease and stroke.The researchers, from the University of Michigan Health System and Baylor University, say the combination of inadequate sleep and obesity has been linked to raised risks of cardiovascular diseases in adults and younger children.
Source: Health News from Medical News Today - March 6, 2014 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news