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Infectious Disease: Epidemics

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Total 445 results found since Jan 2013.

Neurosyphilis in Africa: A systematic review
DiscussionThis is the first systematic review of the literature on neurosyphilis in Africa since the beginning of the HIV epidemic. Neurosyphilis continues to be reported as a manifestation of both early and late syphilis, but the methodological quality of the majority of the included studies was poor. Future well-designed prospective studies are needed to better delineate the incidence and clinical spectrum of neurosyphilis in Africa and to better define interactions with HIV in this setting.
Source: PLoS Neglected Tropical Diseases - August 31, 2017 Category: Tropical Medicine Authors: Michael Marks Source Type: research

Former CDC chief Frieden to head $225m anti-heart disease initiative
Previous US Centers for Disease Control and Prevention director Dr. Tom Frieden said he will head Resolve, a new public health initiative focused on fighting heart disease and stroke which has already raised $225 million in backing from a handful of private philanthropies. The Bill & Melinda Gates Foundation, Bloomberg Philanthropies and the Chan Zuckerberg Initiative have joined in to fund the initiative. Resolve plans to invest in efforts to reduce trans-fats from restaurant menus, which follows up on Frieden’s 2006 efforts to ban trans-fats as the New York City health commissioner. The initiative will also look to...
Source: Mass Device - September 12, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Centers for Disease Control & Prevention (CDC) Source Type: news

Former CDC Chief Leads Global Initiative to Save 100M Lives Former CDC Chief Leads Global Initiative to Save 100M Lives
Former CDC Director Tom Frieden, MD, heads the Resolve to Save Lives initiative, which aims to save lives from heart disease and stroke and prevent epidemics in low- and middle-income countries.Medscape Medical News
Source: Medscape Medical News Headlines - September 13, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Pediatric Strokes: The Who, What, When, and Beyond...: A Patient and Family Guide
The prevalence of pediatric strokes, incidence of delay in treatment, and misdiagnosis has become an epidemic in healthcare. The purpose of this poster presentation is to provide education to healthcare professionals related to the extensive care required for pediatric stroke patients, from diagnosis until adulthood. As healthcare professionals, we must be educated and aware that pediatric strokes (one of the top 10 causes of death in children aged 1-19 years) occur and their recovery includes a multidisciplinary approach. We have developed an educational booklet for patients and parents that includes diagnoses through all...
Source: Journal of Pediatric Surgical Nursing - July 1, 2017 Category: Nursing Tags: Poster Abstracts Source Type: research

Melanocortin neurons: Multiple routes to regulation of metabolism
This article is part of a Special Issue entitled: Melanocortin Receptors - edited by Ya-Xiong Tao.
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - September 19, 2017 Category: Molecular Biology Source Type: research

Obesity epidemic puts 240,000 lives at risk each year
BRITAIN ’S obesity epidemic has put hundreds of thousands at risk of heart disease and stroke, analysis shows.
Source: Daily Express - Health - September 24, 2017 Category: Consumer Health News Source Type: news

Atrial Fibrillation in Heart Failure: a Therapeutic Challenge of Our Times.
Authors: Batul SA, Gopinathannair R Abstract Atrial fibrillation (AF) and heart failure (HF) are growing cardiovascular disease epidemics worldwide. There has been an exponential increase in the prevalence of AF and HF correlating with an increased burden of cardiac risk factors and improved survival rates in patients with structural heart disease. AF is associated with adverse prognostic outcomes in HF and is most evident in mild-to-moderate left ventricular (LV) dysfunction where the loss of "atrial kick" translates into poorer quality of life and increased mortality. In the absence of underlying structural heart...
Source: Korean Circulation Journal - September 29, 2017 Category: Cardiology Tags: Korean Circ J Source Type: research

Photobiomodulation for Traumatic Brain Injury and Stroke
Abstract There is a notable lack of therapeutic alternatives for what is fast becoming a global epidemic of traumatic brain injury (TBI). Photobiomodulation (PBM) employs red or near‐infrared (NIR) light (600–1100nm) to stimulate healing, protect tissue from dying, increase mitochondrial function, improve blood flow, and tissue oxygenation. PBM can also act to reduce swelling, increase antioxidants, decrease inflammation, protect against apoptosis, and modulate microglial activation state. All these mechanisms of action strongly suggest that PBM delivered to the head should be beneficial in cases of both acute and chro...
Source: Journal of Neuroscience Research - November 13, 2017 Category: Neuroscience Authors: Michael R Hamblin Tags: REVIEW Source Type: research

Photobiomodulation for traumatic brain injury and stroke - Hamblin MR.
There is a notable lack of therapeutic alternatives for what is fast becoming a global epidemic of traumatic brain injury (TBI). Photobiomodulation (PBM) employs red or near-infrared (NIR) light (600-1100nm) to stimulate healing, protect tissue from dying,...
Source: SafetyLit - November 16, 2017 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Building on NeuroNEXT: “Next Generation” Clinics to Cure Chronic Neurological Disability
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - November 24, 2017 Category: Neurology Authors: Rajiv R. Ratan Tags: Letter to the Editor Source Type: research

Pediatric Strokes: The Who, What, When, and Beyond...A Patient and Family Guide
Abstract The prevalence of pediatric strokes, incidence of delay in treatment, and misdiagnosis has become an epidemic in healthcare. The purpose of this poster presentation is to provide education to healthcare professionals related to the extensive care required for pediatric stroke patients, from diagnosis until adulthood. As healthcare professionals, we must be educated and aware that pediatric strokes (one of the top 10 causes of death in children aged 1–19 years) occur and their recovery includes a multidisciplinary approach. We have developed an educational booklet for patients and parents that includes diagnose...
Source: Journal of Pediatric Surgical Nursing - July 1, 2017 Category: Nursing Tags: Poster Abstracts Source Type: research

Glycaemic, Blood Pressure and Low Density Lipoprotein Cholesterol Control in Adult Patients with Diabetes in Singapore: A Review of Singapore Literature Over Two Decades.
CONCLUSION: Mirroring global patterns, the glycaemic, BP and LDL-C control in adult diabetic patients in Singapore do not appear to be treated to target in the majority of patients. PMID: 29177366 [PubMed - in process]
Source: Annals of the Academy of Medicine, Singapore - October 1, 2017 Category: General Medicine Authors: Poh Z, Venkataraman K, Toh SE, Low LL Tags: Ann Acad Med Singapore Source Type: research

GSE72278 A novel lineage of adipose tissue regulatory T cells controls obesity and insulin resistance
Contributors : Emilie Stolarczyk ; Charlotte Bailey ; Natividad Garrido-Mesa ; Paul Lavender ; Richard Jenner ; Graham Lord ; Jane HowardSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusThe epidemic of obesity and its associated systemic metabolic complications continues to increase. Adipose tissue (AT)-associated T cells have been proposed to play an important role in the regulation of bodyweight and insulin sensitivity with a link to Th1 or Th2 lineage specification. A specific subset of regulatory T cells (TREGS) plays a critical and non-redundant role in controlling s...
Source: GEO: Gene Expression Omnibus - December 1, 2017 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research

Rate or Rhythm Control of Atrial Fibrillation - Pearls for the Internist.
Abstract Atrial fibrillation is an epidemic in Asia that is increasingly prevalent. Apart from stroke risk stratification and management of anticoagulation, physicians managing this group of patients also need to determine an optimal strategy in terms of rate or rhythm control. With new techniques of catheter ablation to maintain patients in sinus rhythm, patients with atrial fibrillation now have more options for treatment, on top of pharmacological methods. This paper aims to review the current evidence for rate and rhythm control in both general patients and subgroups of interest commonly encountered in clinica...
Source: Annals of the Academy of Medicine, Singapore - November 1, 2017 Category: General Medicine Authors: Huang W, Keng FY, Ching CK Tags: Ann Acad Med Singapore Source Type: research

Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders. KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy INTRODUCTION Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research