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Specialty: Neurology
Condition: Stroke
Education: Academia

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Total 363 results found since Jan 2013.

Long-term motor, functional, and academic outcome following childhood ischemic and hemorrhagic stroke: A large rehabilitation center-based retrospective study
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Source: Developmental Neurorehabilitation - November 13, 2016 Category: Neurology Authors: Estelle Yvon Delphine Lamotte Anne Tiberghien Ingrid Godard Alain Mardaye Anne Laurent-Vannier Maria De Agostini Mathilde Chevignard Source Type: research

Corrigendum to “Risk of depression in patients with chronic rhinosinusitis: A nationwide population-based retrospective cohort study J. Affect. Disord. 206 (2016) 294−299
This study is supported in part by Taiwan Ministry of Health and Welfare Clinical Trial and Research Center of Excellence (MOHW105-TDU-B-212 –133019), Academia Sinica Taiwan Biobank Stroke Biosignature Project (BM10501010037), NRPB Stroke Clinical Trial Consortium (MOST 105–2325-B-039-003), Tseng-Lien Lin Foundation, Taichung, Taiwan, Taiwan Brain Disease Foundation, Taipei, Taiwan, Katsuzo and Kiyo Aoshima Memorial Funds, Japan, Chi na Medical University Hospital, and CMU under the Aim for Top University Plan of the Ministry of Education, Taiwan.
Source: Journal of Affective Disorders - November 9, 2016 Category: Neurology Authors: Che-Lun Hsu, Tang-Chuan Wang, Te-Chun Shen, Yu-Jhen Huang, Cheng-Li Lin, Fung-Chang Sung Source Type: research

Validation of international stroke scales for use by nurses in Greek settings.
CONCLUSIONS: The Greek version of the stroke tools show that both SSS and BI have high internal consistency and reliability and together with the mRS could be used in any Greek stroke care delivery setting. PMID: 27680397 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 28, 2016 Category: Neurology Authors: Theofanidis D Tags: Top Stroke Rehabil Source Type: research

Stroke Treatment Academic Industry Roundtable: The Next Generation of Endovascular Trials Special Report
Conclusions— Research priorities in ET for large vessel occlusion stroke are to improve systems of care, investigate effective adjuvant therapies, and explore whether patient eligibility could be expanded.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Jovin, T. G., Albers, G. W., Liebeskind, D. S., for the STAIR IX Consortium Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Special Report Source Type: research

Noncontrast Computed Tomography Hypodensities Predict Poor Outcome in Intracerebral Hemorrhage Patients Clinical Sciences
Conclusions— The presence of noncontract CT hypodensities at baseline independently predicts poor outcome and comes as a useful and widely available addition to our ability to predict ICH patients’ clinical evolution.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Boulouis, G., Morotti, A., Brouwers, H. B., Charidimou, A., Jessel, M. J., Auriel, E., Pontes-Neto, O., Ayres, A., Vashkevich, A., Schwab, K. M., Rosand, J., Viswanathan, A., Gurol, M. E., Greenberg, S. M., Goldstein, J. N. Tags: Computerized Tomography (CT), Prognosis, Mortality/Survival, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Clinical Sciences Source Type: research

Cerebrospinal Fluid Stanniocalcin-1 as a Biomarker for Alzheimer ’s Disease and Other Neurodegenerative Disorders
AbstractStanniocalcin-1 (STC-1) is a nerve cell-enriched protein involved in intracellular calcium homeostasis regulation. Changes in calcium regulation are hypothesized to play a role in the pathophysiology of Alzheimer ’s disease (AD). The expression of STC-1 increases in response to ischemic stroke, but whether it is altered in neurodegenerative disorder, particularly Alzheimer’s disease (AD), has not been investigated before. We measured STC-1 in cerebrospinal fluid (CSF) samples from a total of 163 individu als including AD, prodromal AD (pAD), mixed AD, stable mild cognitive impairment (sMCI), and diagnoses of ot...
Source: NeuroMolecular Medicine - September 18, 2016 Category: Neurology Source Type: research

Neurofeedback-based motor imagery training for rehabilitation after stroke.
Abstract Mental training, including motor observation and motor imagery, has awakened much academic interest. The presumed functional equivalence of motor imagery and motor execution has given hope that mental training could be used for motor rehabilitation after a stroke. Results obtained from randomized controlled trials have shown mixed results. Approximately half of the studies demonstrate positive effects of motor imagery training but the rest do not show an additional benefit. Possible reasons why motor imagery training has so far not become established as a robust therapeutic approach are discussed in detai...
Source: Der Nervenarzt - August 29, 2016 Category: Neurology Authors: Dettmers C, Braun N, Büsching I, Hassa T, Debener S, Liepert J Tags: Nervenarzt Source Type: research

Exploratory factor analysis of the reintegration to normal living index in a stroke population.
CONCLUSIONS: Previous factor analyses on the RNLI utilizing general disability samples commonly report a two-factor solution. Our data support the presence of a single factor solution across the RNLI within a large sample comprised exclusively of stroke survivors. This suggests that the RNLI acts as more of a unitary measure of quality of life within a stroke sample relative to other disabled samples. PMID: 27486007 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 2, 2016 Category: Neurology Authors: Merz ZC, Van Patten R, Mulhauser K, Fucetola R Tags: Top Stroke Rehabil Source Type: research

Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke Special Reports
Pooled analysis of individual patient data from stroke trials can deliver more precise estimates of treatment effect, enhance power to examine prespecified subgroups, and facilitate exploration of treatment-modifying influences. Analysis plans should be declared, and preferably published, before trial results are known. For pooling trials that used diverse analytic approaches, an ordinal analysis is favored, with justification for considering deaths and severe disability jointly. Because trial pooling is an incremental process, analyses should follow a sequential approach, with statistical adjustment for iterations. Update...
Source: Stroke - July 24, 2016 Category: Neurology Authors: Lees, K. R., Khatri, P., for the STAIR IX Collaborators, Alexandrov, Bivard, Boltze, Broderick, Campbell, Creighton, Fiorella, Furlan, Gorelick, Hess, Kim, Latour, Liebeskind, Luby, Lyden, Lynch, Marshall, Menon, Muir, Palesch, Peng, Pryor, Mocco, Rasmuss Tags: Meta Analysis, Cerebrovascular Disease/Stroke Special Reports Source Type: research

Internal Carotid Artery S-Shaped Curve as a Marker of Fibromuscular Dysplasia in Dissection-Related Acute Ischemic Stroke
Background and Purpose: Craniocervical fibromuscular dysplasia (FMD) is associated with dissections and with S-shaped curves in the internal carotid artery (ICA). We evaluated the occurrence of S-curves in patients presenting with acute strokes due to ICA steno-occlusive dissections. Methods: This was a retrospective review of the interventional databases of two academic tertiary-care institutions. The presence of ICA S-shaped curves, C-shaped curves, 360-degree loops, as well as classic FMD and atherosclerotic changes at the ICA bulb and curve/loop was determined. Cases of carotid dissections were compared with a control ...
Source: Interventional Neurology - July 15, 2016 Category: Neurology Source Type: research

Third European Stroke Science Workshop Special Report
Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a cornerstone of European Stroke Organization’s academic activities and major highlight for researchers in the field. Participants include stroke researchers at all career stages who convene for plenary lectures and discussions, thus facilitating crosstalk among researchers from different fields. As in pr...
Source: Stroke - June 26, 2016 Category: Neurology Authors: Dichgans, M., Planas, A. M., Biessels, G. J., van der Worp, B., Sudlow, C., Norrving, B., Lees, K., Mattle, H. P. Tags: Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Special Report Source Type: research

Novel Treatments in Neuroprotection for Aneurysmal Subarachnoid Hemorrhage
Opinion statement New neuroprotective treatments aimed at preventing or minimizing “delayed brain injury” are attractive areas of investigation and hold the potential to have substantial beneficial effects on aneurysmal subarachnoid hemorrhage (aSAH) survivors. The underlying mechanisms for this “delayed brain injury” are multi-factorial and not fully understood. The most ideal treatment strategies would have the potential for a pleotropic effect positively modulating multiple implicated pathophysiological mechanisms at once. My personal management (RFJ) of patients with aneurysmal subarachnoid hemorrhage...
Source: Current Treatment Options in Neurology - June 19, 2016 Category: Neurology Source Type: research

Academic-industry Collaborations in Translational Stroke Research
Abstract Academic-industry collaborations are an emerging format of translational stroke research. Next to classic contract research models, a multitude of collaboration models has been developed, some of which even allowing for multinational or intercontinental research programs. This development has recently been paralleled by first successful attempts to overcome the translational stroke research road block, such as the unprecedented success of novel endovascular approaches or the advent of the multicenter preclinical trial concept. While the first underlines the role of the industry as a major innovation drive...
Source: Translational Stroke Research - June 13, 2016 Category: Neurology Source Type: research

Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes Clinical Sciences
Conclusions— AF is associated with an unfavorable 90-day outcome among patients with a CES independent of established risk factors and initial stroke severity. This suggests that AF-specific mechanisms affect CES severity and functional status after CES. If confirmed in future studies, further investigation into the underlying pathophysiological mechanisms may provide novel avenues to AF detection and treatment.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Henninger, N., Goddeau, R. P., Karmarkar, A., Helenius, J., McManus, D. D. Tags: Atrial Fibrillation, Etiology, Ischemic Stroke Clinical Sciences Source Type: research

Analysis of Inpatient Thrombophilia Testing for Adults with an Ischemic Stroke or Transient Ischemic Attack and its Impact on Clinical Management (P1.123)
Conclusions: Inpatient thrombophilia testing did not affect management in the vast majority of patients with an ischemic stroke or TIA despite a positive test result. Therefore, by avoiding inpatient testing, healthcare costs may be reduced without affecting patient care.Disclosure: Dr. Gavva has nothing to disclose. Dr. Alberts has received personal compensation for activities with AGA medical, AstraZeneca, Bayer, Pfizer, Bistol-Myers-Squibb, Boehringer Ingelheim, diaDexus, Genentech, KOS, Medicine Company, PDL biopharma, Pfizer, Photothera, Sanofi. Dr. Johnson has nothing to disclose. Dr. Sarode has received personal com...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gavva, C., Alberts, M., Johnson, M., Sarode, R. Tags: Cerebrovascular Disease: Epidemiology Source Type: research