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Condition: Pain
Drug: Morphine

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Total 24 results found since Jan 2013.

Opiate Use After Endoscopic Endonasal Transsphenoidal Surgery
CONCLUSION: Patients undergoing EETS have higher opiate needs compared to those undergoing endoscopic sinus surgery, although the overall requirements are still considered low. Independent risk factors associated with higher opiate use in the immediate postoperative period included current smokers and grade 3 intraoperative cerebrospinal fluid leaks.PMID:34881667 | DOI:10.1177/19458924211061990
Source: American Journal of Rhinology and Allergy - December 9, 2021 Category: ENT & OMF Authors: Tara J Wu Reza Kianian Emmanuel G Villalpando Morcos N Nakhla Christine Wells Anthony P Heaney Marvin Bergsneider Marilene B Wang Source Type: research

M046 direct provocation testing to morphine in a patient with severe allergic symptoms to opioids
We describe a patient with sickle cell disease who has continuously avoided morphine and oxycodone, limiting her therapeutic options during pain crises.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: B. Underwood, A. Assa'ad, K. Risma Source Type: research

Opioid use after endoscopic skull base surgery: A descriptive, prospective, longitudinal cohort study
ConclusionAfter ESBS, greater total opioid use was significantly associated with history of headaches and previous opioid use within 60 days. Overall, opioid use declined among all patients in the postoperative period, but several factors may contribute to longer duration of use.
Source: International Forum of Allergy and Rhinology - July 26, 2021 Category: Allergy & Immunology Authors: Ryan A. Rimmer, Brian Scott, Jasmina Pailet, Nyssa Fox Farrell, Jess C. Mace, Kara Y. Detwiller, Timothy L. Smith, Aclan Dogan, Sachin Gupta, Peter Andersen, Justin Cetas, Mathew Geltzeiler Tags: ORIGINAL ARTICLE Source Type: research

Prescription patterns and opioid usage in sinonasal surgery
ConclusionOpioids are overprescribed after sinonasal surgery. The amount of postoperative opiate prescribed should be greatly reduced and may be based on the specific procedures performed. Improved patient education regarding disposal of excess narcotics may help to curtail future opioid diversion.
Source: International Forum of Allergy and Rhinology - November 5, 2019 Category: Allergy & Immunology Authors: Christopher I. Newberry, Geoffrey C. Casazza, Liese C. Pruitt, Jeremy D. Meier, David E. Skarda, Jeremiah A. Alt Tags: ORIGINAL ARTICLE Source Type: research

Incidence and risk factors for epidural morphine induced pruritus in parturients receiving cesarean section: A prospective multicenter observational study
This study is designed to clarify the incidence of epidural morphine induced pruritus (EMIP) in Chinese Han and Tibetan parturients after cesarean section (CS) and to identify the correlated risk factors. This is a prospective multicenter observational study. Follow-up evaluations were performed at 3 hours, 6 hours, 12 hours, 24 hours, and 48 hours after morphine administration. The primary outcome was EMIP incidence. Other details were also recorded for risk factor screening. Totally 284 parturients receiving CS were enrolled and 247 completed the study. The overall incidence of EMIP was 18.6% (46 in 247). The...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

The impact of a transversus abdominis plane block including clonidine vs. intrathecal morphine on nausea and vomiting after caesarean section: A randomised controlled trial
BACKGROUND Intrathecal morphine (ITM) is a widely used technique for postcaesarean section analgesia but entails a high risk of postoperative nausea and vomiting (PONV). The transversus abdominis plane (TAP) block is an alternative. OBJECTIVE We tested the hypothesis that a TAP block including clonidine reduces the incidence of PONV after caesarean section when compared with ITM. DESIGN A randomised, controlled, double-blinded study. SETTING Geneva University Hospitals, Switzerland, from October 2013 to February 2017. PATIENTS A total of 182 patients undergoing elective caesarean section were studied. Reasons...
Source: European Journal of Anaesthesiology - July 8, 2019 Category: Anesthesiology Tags: Postoperative nausea and vomiting Source Type: research

Allergic Contact Dermatitis To Fentanyl TTS With Good Tolerance To Systemic Fentanyl.
CONCLUSION: We present the case of allergic contact dermatitis (ACD) due to hypersensitivity to fentanyl with good tolerance to buprenorphine. Positive PT in this patient suggests a type IV hypersensitivity mechanism. Allergic reactions to opioids are frequently immediate, but delayed reactions could appear, especially when the drug is administered topically. PMID: 31131754 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - May 29, 2019 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Histamine and Delirium: Current Opinion
This study indicated that switch from H2 blockers to PPIs reduced delirium and, thus, providing an appropriate strategy to combat drug-induced delirium using antiulcer drugs (Fujii et al., 2012). The ventrolateral preoptic nucleus is a sleep-promoting nucleus located in the basal forebrain. A commonly used intravenous anesthetic, propofol, had been reported to induce sleep and augment the firing rate of neurons in ventrolateral GABAergic preoptic nucleus, but the underlining mechanism is yet to be clearly determined. Interestingly, the propofol-induced inhibition of inhibitory postsynaptic currents on noradrenalin-inhibite...
Source: Frontiers in Pharmacology - April 8, 2019 Category: Drugs & Pharmacology Source Type: research

Opioid analgesic use and patient ‐reported pain outcomes after rhinologic surgery
ConclusionPostoperative pain after elective rhinologic surgery appears to peak over the first 3 days and decreases rapidly afterward. Most patients require a few doses of opioid analgesics. Opioid requirements and pain levels did not vary based on surgeon, type and extent of surgery, and demographic factors. Judicious prescribing of opioid medication after rhinologic surgery represents a practical opportunity for rhinologists and otolaryngologists to reduce opioid overprescription and abuse.
Source: International Forum of Allergy and Rhinology - March 27, 2019 Category: Allergy & Immunology Authors: Charles A. Riley, Matthew Kim, Anthony P. Sclafani, Aron Kallush, Klaus Kjaer, Ashutosh S. Kacker, Abtin Tabaee Tags: ORIGINAL ARTICLE Source Type: research

Can Battlefield Acupuncture Improve Colonoscopy Experience?
Conclusions: More data are needed, so potentially more patients can indeed avoid morphine/benzodiazepam-based sedation by use of acupuncture to make colonoscopies safer and more pleasant. PMID: 30377464 [PubMed]
Source: Acupuncture in Medicine - October 1, 2018 Category: Complementary Medicine Authors: Abdelfatah MM, Beacham MC, Freedman M, Tillmann HL Tags: Med Acupunct Source Type: research

What Causes Flushing?
Discussion Flushing is usually thought of as a benign condition such as blushing, but can be quite irritating if it is frequent or persistent (i.e. menopausal hot flashes) or even pathologic (i.e. malignancy). “Flushing is a subjective and sensation of warmth that is accompanied by reddening of the skin anywhere on the body but favors the face, neck, and upper torso…. Flushing can be broadly divided into episodic or persistent. Episodic flashing is mediated by the release of endogenous vasoactive mediators or medications, while persistent flushing result in a fixed facial erythema with telangiectasias and cyano...
Source: PediatricEducation.org - April 30, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

In Defense of Morphine (Part 1)
Discussion, we all know why they performed this study, what they expected it to show, and how it will be cited for years to come. It demonstrates an association between morphine and worse outcomes in patients with ST-elevation acute myocardial infarction (STEMI). I don’t know why everyone has been ganging up on poor old morphine for acute coronary syndrome (ACS)—maybe because it’s been beloved by so many for so long—but while I may not be able to empathize with the hardships of being popular, I sympathize with the hate it’s been receiving and hope to offer some exculpation.   How did we get here?...
Source: EMS 12-Lead - February 17, 2018 Category: Cardiology Authors: Vince DiGiulio Tags: Original Articles Vince DiGiulio Source Type: research