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Total 15 results found since Jan 2013.

Efficacy of the exhalation delivery system with fluticasone in patients who remain symptomatic on standard nasal steroid sprays
ConclusionEDS ‐FLU comparably improves symptoms, irrespective of whether patients are symptomatic while using conventional nasal steroids before treatment.
Source: International Forum of Allergy and Rhinology - April 21, 2021 Category: Allergy & Immunology Authors: Brent A. Senior, Rodney J. Schlosser, John Bosso, Zachary M. Soler Tags: ORIGINAL ARTICLE Source Type: research

Exhalation delivery system with fluticasone improves quality of life and health status: pooled analysis of phase 3 trials NAVIGATE I and II
ConclusionIn this pooled analysis of 2 large pivotal EDS ‐FLU trials, health domain and health utilities improvements were significantly greater with EDS‐FLU than EDS‐PBO and were comparable to population norms.
Source: International Forum of Allergy and Rhinology - May 21, 2020 Category: Allergy & Immunology Authors: Zachary M. Soler, Sam Colman, Fulton F. Velez, Rodney J. Schlosser Tags: ORIGINAL ARTICLE Source Type: research

Eosinophilic esophagitis: Pathophysiology, diagnosis, and management.
Abstract Eosinophilic esophagitis (EoE) is a multifactorial esophageal inflammation, with a genetic predisposition, which combines a deficient esophageal mucosal barrier, an abnormal immune reaction to environmental allergens mediated by Th2 interleukins, immediate esophageal lesions and dysmotility, with secondary remodeling and fibrosis. Symptoms include reflux, abdominal pain, and food impaction, with a variation according to age. Fibroscopy shows major and minor endoscopic and histologic criteria, with a mucosal count≥15 eosinophils/high power field (Eo/hpf). A new entity has been defined, where gastroesopha...
Source: Archives de Pediatrie - February 27, 2019 Category: Pediatrics Authors: Vinit C, Dieme A, Courbage S, Dehaine C, Dufeu CM, Jacquemot S, Lajus M, Montigny L, Payen E, Yang DD, Dupont C Tags: Arch Pediatr Source Type: research

NAVIGATE I: Randomized, Placebo-Controlled, Double-Blind Trial of the Exhalation Delivery System With Fluticasone for Chronic Rhinosinusitis With Nasal Polyps.
CONCLUSIONS: In patients with chronic rhinosinusitis with NP (CRSwNP) who were symptomatic despite high rates of prior intranasal steroid use and/or surgery, EDS-FLU produced statistically significant and clinically meaningful improvements compared to EDS-placebo in multiple subjective and objective outcomes (symptoms, SNOT-22, RSDI, SF-36, PGIC, and NP grade), including all 4 cardinal symptoms of CRSwNP. PMID: 30477309 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - November 27, 2018 Category: ENT & OMF Authors: Sindwani R, Han JK, Soteres DF, Messina JC, Carothers JL, Mahmoud RA, Djupesland PG Tags: Am J Rhinol Allergy Source Type: research

Eds-flu versus traditional nasal steroids for treating chronic rhinosinusitis: summarizing current evidence for symptom benefits
Standard intranasal steroids (INS) are first-line therapy, but yield limited benefit, in treating defining symptoms of CRSw/sNP (congestion, rhinorrhea, facial pain/pressure, anosmia). We compared symptom relief with traditional INS, as summarized in a 2016 Cochrane review, with symptom relief reported in pooled trials with EDS-FLU (exhalation delivery system with fluticasone).
Source: Annals of Allergy, Asthma and Immunology - November 1, 2018 Category: Allergy & Immunology Authors: G. Bensch, J. Messina, H. Sacks, R. Mahmoud Tags: A452 Source Type: research

Severe ketorolac-induced asthma diagnosed by chest CT
Conclusion: This report illustrates both an intravenous NSAID causing severe AERD, and how a chest CT may be instrumental for the diagnosis of life-threatening asthma. (Figure 1)
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Fernandes, V., Regateiro, F. S., Baptista, J. P., Alfaro, T. M., Matos, M. J. Tags: Allergy and immunology Source Type: research

P441 Exhalation delivery system with fluticasone (EDS-FLU) improves peak nasal inspiratory flow (PNIF) in CRSWNP
Nasal polyps cause nasal passage obstruction in CRS leading to the defining symptoms: congestion/obstruction, rhinorrhea, facial pain/pressure, and decreased sense of smell/hyposmia. EDS-FLU was shown to substantially improve several objective and subjective measures in CRSwNP. In this analysis, we examined the effect of EDS-FLU on PNIF to assess nasal passage obstruction.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: E. Schenkel, J. Messina, J. Carothers, P. Djupesland, R. Mahmoud Source Type: research

Safety and efficacy of a bioabsorbable fluticasone propionate –eluting sinus dressing in postoperative management of endoscopic sinus surgery: a randomized clinical trial
ConclusionSinuBand FP was well tolerated and showed evidence of efficacy. A larger study is needed to further evaluate and confirm the benefits of SinuBand FP.
Source: International Forum of Allergy and Rhinology - May 30, 2017 Category: Allergy & Immunology Authors: Gwijde F.J.P.M. Adriaensen, Keng ‐Hua Lim, Wytske J. Fokkens Tags: ORIGINAL ARTICLE Source Type: research

8 Things You Need To Know About Your Body's Energy Levels
By Hallie Levine Your energy makeover starts now It’s no wonder so many of us struggle with energy issues. We go, go, go from morning to night, running on little but grit and caffeine. But it doesn’t have to be that way! “The reality is, you can get a real boost by making a few simple changes,” says Nada Milosavljevic, MD, director of the integrative health program at Massachusetts General Hospital. That’s why we put together this complete guide to all-day energy: It’s packed with proven strategies that will keep you powered up as you plow through your to-do list. You’ll also learn...
Source: Healthy Living - The Huffington Post - May 4, 2017 Category: Consumer Health News Source Type: news

What 5 Nurses Keep In Their Medicine Cabinets
Snooping inside a medicine cabinet while using the bathroom during a party is a particular guilty pleasure.  What eye cream does your host use? What kinds of medications are they on? It’s natural to be curious and often, you’re comparing the regimens of acquaintances to your own. For example, do you have the same emergency first aid stash?   If you’re snooping inside the medicine cabinet of a nurse, you might feel the strong urge to copy what you see. In this case, HuffPost has done the peeking for you: Among the nurses contacted for this story, over-the-counter painkillers, bandages and to...
Source: Science - The Huffington Post - May 12, 2016 Category: Science Source Type: news

Non-culprit coronary vasospasm in a woman affected by Churg–Strauss syndrome presenting with ST-elevation myocardial infarction
A 57-year old Caucasian woman with no cardiovascular risk factor was admitted to our Institution for typical chest pain. According to classification criteria of the American College of Rheumatology [1] (Box 1), she was affected by Churg–Strauss Syndrome (CSS) with nasal polyposis and asthma, treated by oral prednisone, inhaled salmeterol and fluticasone. She also reported allergy to most non-steroidal anti-inflammatory drugs, with previous anaphylactic shock to ibuprofen. A myocardial perfusion scintigraphy performed one month before showed reversible anterolateral wall perfusion defect.
Source: International Journal of Cardiology - August 5, 2014 Category: Cardiology Authors: Gianpiero D'Amico, Luca Nai Fovino, Umberto Cucchini, Luisa Cacciavillani, Sabino Iliceto, Paolo Buja Source Type: research