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Specialty: Respiratory Medicine
Condition: Hypertension

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Total 342 results found since Jan 2013.

Screening Programs for Obstructive Sleep Apnea
AbstractPurpose of the ReviewThe aim of this article is to describe the literature on the rationale, methods, and outcomes of screening programs for obstructive sleep apnea (OSA).Recent FindingsThe evidence does not support screening for OSA in the general population. Instead, targeted case finding is advised among the following high-risk groups: patients with obesity, congestive heart failure, atrial fibrillation, treatment refractory hypertension, type 2 diabetes, stroke, nocturnal dysrhythmias, and pulmonary hypertension. However, the method of screening remains unclear with some studies suggesting the use of questionna...
Source: Current Respiratory Care Reports - April 11, 2017 Category: Respiratory Medicine Source Type: research

Diagnosing and managing sleep apnea in patients with chronic cerebrovascular disease: a randomized trial of a home-based strategy
ConclusionsPatients with cerebrovascular disease and hypertension have a high prevalence of OSA. The use of portable polysomnography, and auto-titrating CPAP in the patients ’ homes, improved both the diagnosis and the treatment for sleep apnea compared with usual care but did not lower blood pressure.
Source: Sleep and Breathing - April 6, 2017 Category: Respiratory Medicine Source Type: research

CHA2DS2 ‐VASc Scores Predict Major Adverse Cardiovascular Events in Patients with Chronic Obstructive Pulmonary Disease
Conclusion: Early lifestyle modifications and antithrombotic therapy may be essential for COPD patients at a high risk of MACEs, i.e. those with CHA2DS2‐VASc scores ≥ 6. This article is protected by copyright. All rights reserved.
Source: The Clinical Respiratory Journal - March 6, 2017 Category: Respiratory Medicine Authors: Hean Ooi, Li ‐Hsiou Chen, Yung‐Lun Ni, Huan‐Ting Shen, Yen‐Hsien Lee, Yi‐Chun Chu, Ke‐Chih Fang, I‐ Hung Chen, Shu‐Lan Hsu, Hsing‐Chun Chen, Chien‐Hsiu Huang, Kuo‐Sheng Fan, Chun‐Liang Lai, Liang‐Wen Hang Tags: Original Article Source Type: research

Fine Particulate Air Pollution and Daily Mortality: A Nationwide Analysis in 272 Chinese Cities.
CONCLUSIONS: This nationwide investigation provided robust evidence of the associations between short-term exposure to PM2.5 and increased mortality from various cardiopulmonary diseases in China. The magnitude of associations was lower than those reported in Europe and North America. PMID: 28248546 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - February 28, 2017 Category: Respiratory Medicine Authors: Chen R, Yin P, Meng X, Liu C, Wang L, Xu X, Ross JA, Tse LA, Zhao Z, Kan H, Zhou M Tags: Am J Respir Crit Care Med Source Type: research

Idiopathic and Systemic Sclerosis associated Pulmonary Arterial Hypertension: A Comparison of Demographic, Haemodynamic and Magnetic Resonance Imaging Characteristics and Outcomes.
CONCLUSION: The reasons for poorer outcomes in SSc-PAH are likely to be multifactorial including, but not limited to, older age and reduced gas transfer. PMID: 28223154 [PubMed - as supplied by publisher]
Source: Chest - February 17, 2017 Category: Respiratory Medicine Authors: Ramjug S, Hussain N, Hurdman J, Billings C, Charampopoulos A, Elliot CA, Kiely DG, Sabroe I, Rajaram S, Swift AJ, Condliffe R Tags: Chest Source Type: research

Is obstructive sleep apnea associated with the presence of intracranial cerebral atherosclerosis?
ConclusionsOur findings suggest that moderate to severe OSA is associated with the presence of ICAS in patients with suspected OSA.
Source: Sleep and Breathing - February 6, 2017 Category: Respiratory Medicine Source Type: research

Stratification of cardiovascular risk in patients with atrial fibrillation and obstructive sleep apnea —validity of the 2MACE score
ConclusionOSA prevalence is increased in AF patients and is associated with an increase 2MACE score —an indicator of major cardiovascular events. There is a linear relationship between severity of OSA and increasing 2MACE scores, indicating increasing cardiovascular risk related to OSA severity.
Source: Sleep and Breathing - February 1, 2017 Category: Respiratory Medicine Source Type: research

The role of the Nox4-derived ROS-mediated RhoA/Rho kinase pathway in rat hypertension induced by chronic intermittent hypoxia
ConclusionHypertension can be induced by CIH in SD rats. The CIH-induced elevation of BP is at least partially mediated via the Nox4-induced ROS/RhoA/ROCK pathway.
Source: Sleep and Breathing - January 10, 2017 Category: Respiratory Medicine Source Type: research

The role of physical exercise in obstructive sleep apnea
ABSTRACT Obstructive sleep apnea (OSA) is a common clinical condition, with a variable and underestimated prevalence. OSA is the main condition associated with secondary systemic arterial hypertension, as well as with atrial fibrillation, stroke, and coronary artery disease, greatly increasing cardiovascular morbidity and mortality. Treatment with continuous positive airway pressure is not tolerated by all OSA patients and is often not suitable in cases of mild OSA. Hence, alternative methods to treat OSA and its cardiovascular consequences are needed. In OSA patients, regular physical exercise has beneficial effects other...
Source: Jornal Brasileiro de Pneumologia - January 9, 2017 Category: Respiratory Medicine Source Type: research

An uncommon tomographic association: amiodarone pulmonary toxicity and adenocarcinoma
ABSTRACT Obstructive sleep apnea (OSA) is a common clinical condition, with a variable and underestimated prevalence. OSA is the main condition associated with secondary systemic arterial hypertension, as well as with atrial fibrillation, stroke, and coronary artery disease, greatly increasing cardiovascular morbidity and mortality. Treatment with continuous positive airway pressure is not tolerated by all OSA patients and is often not suitable in cases of mild OSA. Hence, alternative methods to treat OSA and its cardiovascular consequences are needed. In OSA patients, regular physical exercise has beneficial effects other...
Source: Jornal Brasileiro de Pneumologia - January 9, 2017 Category: Respiratory Medicine Source Type: research

Pulmonary fat embolism of neoplastic origin
ABSTRACT Obstructive sleep apnea (OSA) is a common clinical condition, with a variable and underestimated prevalence. OSA is the main condition associated with secondary systemic arterial hypertension, as well as with atrial fibrillation, stroke, and coronary artery disease, greatly increasing cardiovascular morbidity and mortality. Treatment with continuous positive airway pressure is not tolerated by all OSA patients and is often not suitable in cases of mild OSA. Hence, alternative methods to treat OSA and its cardiovascular consequences are needed. In OSA patients, regular physical exercise has beneficial effects other...
Source: Jornal Brasileiro de Pneumologia - January 9, 2017 Category: Respiratory Medicine Source Type: research

Echocardiography for defining the right ventricular contractile reserve in healthy subjects
Conclusions: These results provide age- and sex-related limits of normal RV contractile reserve as assessed by stress echocardiographic PASP, TAPSE, S and TAPSE/PASP. Right ventricular contractile reserve, however measured, correlates with exercise capacity.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: D'Alto, M., Pavelescu, A., Romeo, E., Argiento, P., Di Marco, G. M., Correra, A., Mattera Iacono, A., Russo, M. G., Naeije, R. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Prevalence of common diseases in COPD patients versus lung-healthy control subjects: Results from the German COSYCONET study
COSYCONET investigates the interrelationship of COPD and comorbidities with regard to course and prognosis of the disease. The present analysis examined the prevalence of selected common diseases in the COPD cohort compared to apparently lung-healthy subjects from the population-based reference cohorts KORA and SHIP.Spirometry was performed in all subjects and COPD patients were graded according to GOLD criteria. Subjects from KORA/SHIP without known COPD, asthma or chronic bronchitis and with FEV1/FVC≥0.7 were regarded as apparently lung-healthy. Prevalences of myocardial infarction, stroke, diabetes, hypertension, obe...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Karrasch, S., Obst, A., Söhler, S., Thorand, B., Huth, C., Ladwig, K.-H., Flexeder, C., Wacker, M., Peters, A., Heinrich, J., Ewert, R., Nowak, D., Jörres, R. A., Vogelmeier, C., Gläser, S., Schulz, H., COSYCONET Study Group Tags: 6.1 Epidemiology Source Type: research

MRI derived left atrial volume index predicts treatment response in patients with PAH
Conclusion: This study shows that in patients meeting the haemodynamic criteria for PAH, patients with an elevated LA volume had poor response to PAH therapy. Further work to better characterize this PAH phenotype and recognize the importance of comorbidities in predicting response to therapy is required.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Tubman, E., Sproson, T., Capener, D., Condliffe, R., Elliot, C., Charalampopolous, A., Kiely, D., Jim, W., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Cardio-metabolic disorder in grandparents associated with asthma in offspring: Results from a European 3-generation analysis
Conclusion: These preliminary results are similar to those observed previously in Northern-Europe. Grand-father CMD was associated with subsequent asthma in offspring independently of a family history of asthma. This may have important implications with regard to public health intervention.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Carsin, A.-E., Real, F., Basagana, X., Accordini, S., Dharmage, S., Schlünssen, V., Benediktsdottir, B., Leynaert, B., Janson, C., Sunyer, J., Dratva, J., Jarvis, D., Svanes, C. Tags: 6.4 Genes and Environment Source Type: research