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Specialty: Urology & Nephrology
Condition: Hypertension

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Total 232 results found since Jan 2013.

Fabry nephropathy: a review ¿ how can we optimize the management of Fabry nephropathy?
Fabry disease is a rare, X-linked, lysosomal storage disease caused by mutations in the gene encoding the enzyme alpha-galactosidase A. Complete or partial deficiency in this enzyme leads to intracellular accumulation of globotriaosylceramide (Gb3) and related glycosphingolipids in many cell types throughout the body, including the kidney. Progressive accumulation of Gb3 in podocytes, epithelial cells and the tubular cells of the distal tubule and loop of Henle contribute to the renal symptoms of Fabry disease, which manifest as proteinuria and reduced glomerular filtration rate leading to chronic kidney disease and progre...
Source: BMC Nephrology - May 6, 2014 Category: Urology & Nephrology Authors: Stephen WaldekSandro Feriozzi Source Type: research

Cognition may be related to arterial pulsatility index in HD patients.
Conclusion: In well-dialyzed hemodialysis patients with no history of stroke or dementia, CCAPI may correlate with cognitive function and represent a marker for underlying cerebral microvascular disease. PMID: 24780553 [PubMed - in process]
Source: Clinical Nephrology - May 1, 2014 Category: Urology & Nephrology Authors: Post JB, Morin KG, Handrakis JP, Rivera DR, Yen C, Sano M, Spungen AM Tags: Clin Nephrol Source Type: research

Awareness of Kidney Disease among US Adults: Findings from the 2011 Behavioral Risk Factor Surveillance System.
Conclusion: The overall awareness of kidney disease was low in the general population. Efforts are needed to promote the awareness and early detection of kidney disease in public health services and clinical practice. © 2014 S. Karger AG, Basel. PMID: 24732234 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - April 12, 2014 Category: Urology & Nephrology Authors: Li C, Wen XJ, Pavkov ME, Zhao G, Balluz LS, Ford ES, Williams D, Gotway CA Tags: Am J Nephrol Source Type: research

Hypertension in hemodialysis patients treated with atenolol or lisinopril: a randomized controlled trial
Conclusions Among maintenance dialysis patients with hypertension and left ventricular hypertrophy, atenolol-based antihypertensive therapy may be superior to lisinopril-based therapy in preventing cardiovascular morbidity and all-cause hospitalizations. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases; ClinicalTrials.gov number: NCT00582114)
Source: Nephrology Dialysis Transplantation - February 28, 2014 Category: Urology & Nephrology Authors: Agarwal, R., Sinha, A. D., Pappas, M. K., Abraham, T. N., Tegegne, G. G. Tags: Intra- and Extracorporeal Treatments of Kidney Failure Source Type: research

Home Blood Pressure Monitoring in CKD
Hypertension is common in patients with chronic kidney disease (CKD) and the prevalence increases with declining kidney function. Hypertension management is particularly important due to the increased risk of cardiovascular disease and stroke in the CKD population. Most clinical decisions for blood pressure (BP) management are based on BP readings in the office or dialysis unit. These BP readings often are inaccurate. Home BP monitoring provides more data than conventional clinic or dialysis-unit BP measurements and is relatively easy to accomplish, is cost-effective, and has been shown to have an increasing role in the ma...
Source: American Journal of Kidney Diseases - February 14, 2014 Category: Urology & Nephrology Authors: Debbie L. Cohen, Yonghong Huan, Raymond R. Townsend Tags: In Practice Source Type: research

Chlorthalidone for Poorly Controlled Hypertension in Chronic Kidney Disease: An Interventional Pilot Study.
In conclusion, among people with moderate to advanced CKD with poorly controlled hypertension, chlorthalidone may significantly reduce BP via volume contraction; a randomized trial is needed to define the risks and benefits. Adverse effects may occur within a few weeks and should be carefully monitored. © 2014 S. Karger AG, Basel. PMID: 24526255 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - February 11, 2014 Category: Urology & Nephrology Authors: Agarwal R, Sinha AD, Pappas MK, Ammous F Tags: Am J Nephrol Source Type: research

Incident ESRD and Treatment-Resistant Hypertension: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study
Conclusions: Individuals with treatment-resistant hypertension are at increased risk for ESRD. Appropriate clinical management strategies are needed to treat treatment-resistant hypertension in order to preserve kidney function in this high-risk group.
Source: American Journal of Kidney Diseases - January 2, 2014 Category: Urology & Nephrology Authors: Rikki M. Tanner, David A. Calhoun, Emmy K. Bell, C. Barrett Bowling, Orlando M. Gutiérrez, Marguerite R. Irvin, Daniel T. Lackland, Suzanne Oparil, William McClellan, David G. Warnock, Paul Muntner Tags: Pathogenesis and Treatment of Kidney Disease Source Type: research

Renovascular hypertension: A report of 21 cases.
Abstract Renovascular hypertension (RVH) is among the most common forms of secondary hypertension. We studied 21 patients (eight male and 13 female) with RVH who were encountered during a period of 16 years. The average age of the patients was 34.75 years. Trans-renal Doppler ultrasound confirmed the diagnosis of renovascular stenosis (RAS) as the cause of RVH in 95% of the patients. Computed tomography angiography was performed in ten cases, which confirmed the diagnosis in all these cases. Magnetic resonance angiography was performed in only three patients. Renal scintigraphy was performed in 11 patients, with D...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 1, 2014 Category: Urology & Nephrology Authors: Labidi J, Touat D, Abdelghanim K, Ajili F, Ariba YB, Abdelhafidh NB, Louzir B, Othmani S Tags: Saudi J Kidney Dis Transpl Source Type: research

Specific Management of Anemia and Hypertension in Renal Transplant Recipients: Influence of Renin-Angiotensin System Blockade.
Conclusions: This study provides insight into the safety of RAS inhibition and Hb correction with an erythrocyte-stimulating agent in kidney transplant recipients. © 2013 S. Karger AG, Basel. PMID: 24356394 [PubMed - as supplied by publisher]
Source: American Journal of Nephrology - December 19, 2013 Category: Urology & Nephrology Authors: Salzberg DJ, Karadsheh FF, Haririan A, Reddivari V, Weir MR Tags: Am J Nephrol Source Type: research

Risk of Stroke in Long-term Dialysis Patients Compared With the General Population
Conclusions: Patients undergoing dialysis are at elevated risk of stroke. Patients undergoing PD appear to be less likely to develop hemorrhagic stroke than those undergoing HD. Comprehensive control of hypertension and diabetes is necessary when delivering dialysis treatment.
Source: American Journal of Kidney Diseases - December 2, 2013 Category: Urology & Nephrology Authors: Hsi-Hao Wang, Shih-Yuan Hung, Junne-Ming Sung, Kuan-Yu Hung, Jung-Der Wang Tags: Dialysis Source Type: research

Increased risk of ischemic stroke among women with bladder pain syndrome/interstitial cystitis: A cohort study from Taiwan
ConclusionsOur study demonstrates an association between BPS/IC and a subsequent ischemic stroke diagnosis among women in Taiwan. Neurourol. Urodynam. © 2013 Wiley Periodicals, Inc.
Source: Neurourology and Urodynamics - October 24, 2013 Category: Urology & Nephrology Authors: Shiu‐Dong Chung, Sudha Xirasagar, Ching‐Chun Lin, Wells Ling, Hsien‐Chang Li, Herng‐Ching Lin Tags: Original Clinical Article Source Type: research

Do higher dialysate calcium concentrations increase vascular stiffness in haemodialysis patients as measured by aortic pulse wave velocity?
Background: Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chronic increase in arterial stiffness. We therefore looked at changes in arterial stiffness in established haemodialysis patients to determine whether there was a threshold effect of dialysate calcium concentration linked to change in arterial stiffness. Methods: We performed pulse wave velocity measurements six months apart in patients dialysing with calcium concentrations of 1.0, 1.25, 1.35 and>=1.5 mmol/l. R...
Source: BMC Nephrology - September 8, 2013 Category: Urology & Nephrology Authors: Evangelia CharitakiAndrew Davenport Source Type: research

Prevalence of Apparent Treatment-Resistant Hypertension among Individuals with CKD.
CONCLUSIONS: This study highlights the high prevalence of apparent treatment-resistant hypertension among individuals with CKD. PMID: 23868902 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - July 18, 2013 Category: Urology & Nephrology Authors: Tanner RM, Calhoun DA, Bell EK, Bowling CB, Gutiérrez OM, Irvin MR, Lackland DT, Oparil S, Warnock D, Muntner P Tags: Clin J Am Soc Nephrol Source Type: research

Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses
Salt seems to get the most press, but potassium is an important player in the prevention of vascular disease. This systematic review of 22 RCTs and 11 cohort studies shows that systolic blood pressure was reduced by 7.16 (1.91 to 12.41) mm Hg when the potassium intake was 90-120 mmol/day, without any dose response. Furthermore, there was a 24% lower risk of stroke. The results suggest that patients without impaired renal excretion of potassium would potentially see the most benefit with respect to hypertension and stroke prevention with increased potassium intake. : Effect of lower sodium intake on health: systematic revi...
Source: Nephrology Now - July 15, 2013 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: General Nephrology Hypertension Source Type: research

Effect of lower sodium intake on health: systematic review and meta-analyses
This is another article that supports the literature for reduction in salt intake for overall population health. This systematic further shows that not only does salt lower blood pressure, but there are no adverse effects on lipids, catecholamine levels of renal function. Furthermore, it is associated with lower risk of stroke and fatal coronary heart disease in adults. : Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis. Systematic Review: Vitamin D and C...
Source: Nephrology Now - July 15, 2013 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: General Nephrology Hypertension Source Type: research