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Condition: Hypertension
Procedure: Cardiac Catheterization

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Total 178 results found since Jan 2013.

Abstract 47: Presentation and Outcomes of Women Veterans with Suspected Ischemia and Nonobstructive Coronary Artery Disease: Insights from the VA Clinical Assessment Reporting and Tracking Program. Poster Session I
Conclusion: Between October 2007 and September 2011, 23% of women veterans undergoing catheterization for suspected ischemia had non-obstructive CAD. In contrast to non-VA studies, adverse clinical outcomes and re-hospitalization rates for chest pain were less frequent. These findings may represent systematic differences in treatment and follow-up care of women veterans between VA and non-VA healthcare systems.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Nkonde-Price, C., Plomondon, M., Maddox, T. M., Rumsfeld, J., Duvernoy, C. Tags: Poster Session I Source Type: research

Impact of glomerular filtration rate on clinical outcomes following carotid artery revascularization in 11,832 patients from the care registry®
Conclusions: CKD patients have a greater number of comorbidities, and worse unadjusted in‐hospital and 30‐day outcomes, CKD was not, however, an independent predictor of in‐hospital and 30‐day outcomes after carotid artery revascularization. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - July 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Luis Gruberg, Allen Jeremias, John H. Rundback, H. Vernon Anderson, John A. Spertus, Kevin F. Kennedy, Kenneth A. Rosenfield Tags: Original Study Source Type: research

Right ventricular dysfunction in chronic thromboembolic obstruction of the pulmonary artery: a pressure-volume study using the conductance catheter
Pressure-volume loops describe dynamic ventricular performance, relevant to patients with and at risk of pulmonary hypertension. We used conductance catheter-derived pressure-volume loops to measure right ventricular (RV) mechanics in patients with chronic thromboembolic pulmonary arterial obstruction at different stages of pathological adaptation. Resting conductance catheterization was performed in 24 patients: 10 with chronic thromboembolic pulmonary hypertension (CTEPH), 7 with chronic thromboembolic disease without pulmonary hypertension (CTED), and 7 controls. To assess the validity of conductance measurements, RV vo...
Source: Journal of Applied Physiology - February 15, 2014 Category: Physiology Authors: McCabe, C., White, P. A., Hoole, S. P., Axell, R. G., Priest, A. N., Gopalan, D., Taboada, D., MacKenzie Ross, R., Morrell, N. W., Shapiro, L. M., Pepke-Zaba, J. Tags: ARTICLES Source Type: research

Impact of Glomerular filtration rate on clinical outcomes after carotid artery revascularization in 11,832 patients from the CARE registry
ConclusionsPatients with CKD have a greater number of comorbidities and worse unadjusted in‐hospital and 30‐day outcomes; CKD was not, however, an independent predictor of in‐hospital and 30‐day outcomes after carotid artery revascularization. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - May 3, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Luis Gruberg, Allen Jeremias, John H. Rundback, H. Vernon Anderson, John A. Spertus, Kevin F. Kennedy, Kenneth A. Rosenfield Tags: Original Studies Source Type: research

Effect of Acute Arteriolar Vasodilation on Capacitance and Resistance in Pulmonary Arterial Hypertension.
Conclusions: In vasoresponsive PAH, PVC is a function of the pressure response of the vasoconstricted arterioles to stroke volume. Immediately upon vasodilation, the capacitance increases markedly. The compliance vessels are thus the same as the resistance vessels. The immediate reduction in Pa pressure during NO suggests that large vessel remodeling is not a major contributor to systolic pressure in these patients. PMID: 25340330 [PubMed - as supplied by publisher]
Source: Chest - October 23, 2014 Category: Respiratory Medicine Authors: Newman JH, Brittain EL, Robbins IM, Hemnes AR Tags: Chest Source Type: research

Prostanoids But Not Oral Therapies Improve Right Ventricular Function in Pulmonary Arterial Hypertension
Conclusions Right ventricular function improves after therapy with regimens including prostanoids but not oral-only regimens. Patients with the least compensated RV function at diagnosis might derive the most benefit from therapy. Larger studies are needed to determine whether changes in RVSWI after therapy are associated with outcomes.
Source: JACC: Heart Failure - November 3, 2014 Category: Cardiology Source Type: research

Left ventricular systolic torsion is correlated to right ventricular dilation in pulmonary hypertension patients
Conclusion: We concluded that left ventricular torsion which plays a key role in left ventricular systolic function and stroke volume is affected in PH patients with MPAP higher than 35 mmHg and is correlated to right ventricular dilation.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Lamia, B., Molano, L. C., Cuvelier, A., Viacroze, C., Muir, J.-F. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Abstract P104: Oxygen Drastically Increases Cardiac Output Without Changing Mean Pulmonary Arterial Pressure in a Patient With Severe, Progressive Pulmonary Hypertension Session Title: Onsite Poster Competition I With Reception
Conclusion: Our patient had no significant change in mPAP facing oxygen-induced decrease in PVR. Instead, there was a marked increase in RV CO explainable only by an increase in RV SV facing decreased RV afterload, as HR decreased with oxygen. These findings are consistent with the patient’s class 1 exercise capacity despite having severe PH, indicating an ability to increase CO with activity and suggesting a positive response to medications and better prognosis. Our case shows the importance of assessing hemodynamic data in the workup and management of PH. We propose using TTE assessment of CO coupled with 100% oxygen a...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Dan Zheng, Thomas Roe Tags: Poster Abstract Presentations Source Type: research

Prognostic value of hemodynamics following treatment initiation in pulmonary arterial hypertension
Conclusions: Stroke volume index and right atrial pressure at first follow-up catheterization were the best hemodynamic predictors of death or transplantation. These variables should be further validated as treatment targets in a prospective study.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Weatherald, J., Adir, Y., Boucly, A., Savale, L., Simonneau, G., Montani, D., Jaïs, X., Humbert, M., Chemla, D., Sitbon, O., Herve, P. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Haemodynamic effects of exercise therapy in stable, optimally treated pulmonary arterial hypertension
Conclusions: Provisional results suggest exercise therapy in PAH has a positive effect on the pressure-flow relationship in the pulmonary circulation, leading to reduced stress on the right ventricle on exertion. This change may improve long term outcomes.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: MacKenzie, A., Ford, J., Jayasekera, G., Crowe, T., Peacock, A., Church, C., Johnson, M. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RV stroke volume index and trends for improvement in myocardial remodelling in patients with CTEPH. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodelling.RésuméContexteLes effets du traitement par le riociguat sur le métabolisme, la perfusion et le débit du ventricule droit (VD) chez les patients atteints d’hypertension pulmonaire thromboembolique chronique (HPTC) sont inconnus. Dans la présente étude, nous analysons les changements aux ventriculaires droits associés au traitement par le riociguat.Méthod...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research

Late Breaking Abstract - Balloon Pulmonary Angioplasty for the Treatment of Non Operable Chronic Thromboembolic Pulmonary Hypertension - Initial experience of a Belgian Center
Conclusion: In our cohort, we demonstrated that BPA improves most of the haemodynamics variables, including stroke volume index and pulmonary arterial compliance, without severe adverse events. Further studies for the long term efficacy of BPA are required.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Godinas, L., Lawrence, B., Werner, B., Catharina, B., Mathias, L., Marion, D., Geert, M. Tags: Pulmonary hypertension Source Type: research

Vena cava backflow and right ventricular stiffness in pulmonary arterial hypertension
Vena cava backflow is a well-recognised clinical hallmark of right ventricular failure in pulmonary arterial hypertension (PAH). Backflow may result from tricuspid regurgitation during right ventricular systole or from impaired right ventricular diastolic filling during atrial contraction. Our aim was to quantify the forward and backward flow in the vena cava and to establish the main cause in PAH. In 62 PAH patients, cardiac magnetic resonance measurements provided volumetric flows (mL·s–1) in the superior and inferior vena cava; time integration of flow gave volume. The "backward fraction" was defined as the...
Source: European Respiratory Journal - October 16, 2019 Category: Respiratory Medicine Authors: Marcus, J. T., Westerhof, B. E., Groeneveldt, J. A., Bogaard, H. J., de Man, F. S., Vonk Noordegraaf, A. Tags: Pulmonary vascular disease Original Articles: Pulmonary hypertension Source Type: research

Plasma proteoglycan prolargin in diagnosis and differentiation of pulmonary arterial hypertension
ConclusionsPlasma prolargin levels differentiate PAH patients from controls and the other investigated dyspnoea groups including HF. Its potential in PAH differentiation may be enhanced by inclusion in a multi ‐marker panel. Larger studies are needed to evaluate its discriminative ability of PAH in relation to other dyspnoea aetiologies and its potential role in PAH risk stratification and pathobiology.
Source: ESC Heart Failure - January 5, 2021 Category: Cardiology Authors: Mattias Arvidsson, Abdulla Ahmed, Habib Bouzina, G öran Rådegran Tags: Original Research Article Source Type: research