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Total 497 results found since Jan 2013.

Early and Continuous Neurologic Improvements after Intravenous Thrombolysis Are Strong Predictors of Favorable Long-term Outcomes in Acute Ischemic Stroke
Background: Intravenously administered tissue plasminogen activator (IV tPA) remains the only approved therapeutic agent for arterial recanalization in acute ischemic stroke (AIS). Considerable proportion of AIS patients demonstrate changes in their neurologic status within the first 24 hours of intravenous thrombolysis with IV tPA. However, there are little available data on the course of clinical recovery in subacute 2- to 24-hour window and its impact. We evaluated whether neurologic improvement at 2 and 24 hours after IV tPA bolus can predict functional outcomes in AIS patients at 3 months.Methods: Data for consecutive...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Leonard LL. Yeo, Prakash Paliwal, Hock L. Teoh, Raymond C. Seet, Bernard PL. Chan, Benjamin Wakerley, Shen Liang, Rahul Rathakrishnan, Vincent F. Chong, Eric YS. Ting, Vijay K. Sharma Tags: Original Articles Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Conveniently-Grasped Field Assessment Stroke Triage (CG-FAST): A Modified Scale to Detect Large Vessel Occlusion Stroke
Conclusions: CG-FAST scale could be an effective and simple scale for accurate identification of LVOS among AIS patients. Introduction Large vessel occlusion stroke (LVOS) often leads to severe disability and mortality. Although endovascular therapy (EVT) has been proved to be effective for LVOS patients (1–9), especially in anterior circulation, its benefit is highly time-dependent (10, 11). As hospitals with around-the-clock endovascular capability are scarce in many parts of the world and patients admitted directly to a CSC would have better outcomes than those receiving drip and ship treatment (12, 13), t...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Ischemic Stroke Outcomes in Oman: Experience of a University Hospital Based Stroke Registry (P6.278)
Conclusions:Ischemic stroke in Oman reflects the high morbidity/mortality seen in most communities in the region. Characteristics of incident stroke such as stroke recurrence, type, severity and cardiovascular comorbidity are likely the major determinants of stroke outcome. A relatively lower prevalence of extracranial artery disease and possible greater prevalence of multiple stroke mechanisms may also influence on outcomes and merit further study.Disclosure: Dr. Gujjar has nothing to disclose. Dr. Ramachandiran has nothing to disclose. Dr. Al-Asmi has nothing to disclose. Dr. Ganguly has nothing to disclose. Dr. Shoaib h...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gujjar, A., Ramachandiran, N., Al-Asmi, A., Ganguly, S., Shoaib, R., Al-Asmi, A. Tags: Cerebrovascular Disease Health Services Research Source Type: research

Prevalence of Asymptomatic Cerebral Aneurysm in General population and Ischemic Stroke Patient (I2-4A)
Conclusions: CA was more common in ischemic stroke patients than general population, especially in the 7th decade. Among the various vascular risk factors, hypertension was only correlated with increased prevalence of CA in ischemic stroke patients.Disclosure: Dr. Kim has nothing to disclose. Dr. Oh has nothing to disclose. Dr. Han has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kim, J. H., Oh, Y.-J., Han, S. W., Lee, J. Y., Lee, K.-Y. Tags: Management of Asymptomatic Cerebrovascular Lesions Data Blitz Presentations Source Type: research

Prevalence of Asymptomatic Cerebral Aneurysm in General population and Ischemic Stroke Patient (S47.007)
Conclusions: CA was more common in ischemic stroke patients than general population, especially in the 7th decade. Among the various vascular risk factors, hypertension was only correlated with increased prevalence of CA in ischemic stroke patients.Disclosure: Dr. Kim has nothing to disclose. Dr. Oh has nothing to disclose. Dr. Han has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kim, J. H., Oh, Y.-J., Han, S. W., Lee, J. Y., Lee, K.-Y. Tags: Cerebrovascular Disease and Interventional Neurology Source Type: research

Stroke Care during the COVID-19 Pandemic: International Expert Panel Review
This study, prepared by a large international panel of stroke experts, assesses the rapidly growing research and personal experience with COVID-19 stroke and offers recommendations for stroke management in this challenging new setting: modifications needed for prehospital emergency rescue and hyperacute care; inpatient intensive or stroke units; posthospitalization rehabilitation; follow-up including at-risk family and community; and multispecialty departmental developments in the allied professions.Summary: The severe acute respiratory syndrome coronavirus 2 uses spike proteins binding to tissue angiotensin-converting enz...
Source: Cerebrovascular Diseases - March 23, 2021 Category: Neurology Source Type: research

E-136 endovascular rescue therapy post-stentriever use in large vessel occlusion; real world experience from a regional stroke network
ConclusionsTranslation of clinical trial results into real world experience is feasible and reiterates the unmet need and importance of continuing innovation to keep on improving upon current thrombectomy devices.DisclosuresK. Patel: None. P. Bhuva: None. P. Hansen: None. R. Gianatasio: None. T. Shams: None. V. Janardhan: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Patel, K., Bhuva, P., Hansen, P., Gianatasio, R., Shams, T., Janardhan, V. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Presence and extent of coronary calcified plaque evaluated by coronary computed tomographic angiography are independent predictors of ischemic stroke in patients with suspected coronary artery disease
Abstract Although ischemic stroke and coronary artery disease (CAD) share common risk factors and pathophysiology, the risk of stroke in patients with CAD remains unclear. We sought to evaluate the risk of ischemic stroke in patients with suspected CAD according to coronary computed tomographic angiography (CCTA) and single-photon emission computed tomography (SPECT) findings. Presence, severity, and extent of CAD were evaluated in 1137 patients with suspected CAD who underwent CCTA and SPECT. Primary outcome was the occurrence of ischemic stroke. During follow-up (median 26 months), ischemic stroke was obse...
Source: The International Journal of Cardiovascular Imaging - September 17, 2015 Category: Radiology Source Type: research

Early Surgery for Infective Endocarditis with Stroke Does Not Increase Post-operative Neurological Complications: What are We Waiting For? (S29.007)
Conclusions:In IE patients with acute stroke, early surgery does not appear to increase post-operative neurological complications.Disclosure: Dr. Zhang has nothing to disclose. Dr. Cho has nothing to disclose. Dr. Marquardt has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Wisco has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Zhang, L., Cho, S., Marquardt, R., Hussain, M., Uchino, K., Wisco, D. Tags: Cerebrovascular Disease and Interventional Neurology: Critical Care and Hemorrhage Source Type: research

Susceptibility vessel sign in subacute stroke patients with large vessel occlusion
CONCLUSION: In subacute stroke patients, the occurrence rate of SVS sign in CE group was lower than that of LAA group. The significance of SVS sign in the differentiation of stroke subtype needs further validation.PMID:34916694
Source: Atherosclerosis - December 17, 2021 Category: Cardiology Authors: G Y Ren X M Wu Y Li J Y Li W P Sun Y N Huang Source Type: research

Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African American Population with Ischemic Stroke (P02.044)
CONCLUSIONS: In this study the prevalence of LVSD in AA population with ischemic stroke was 22.45%. Among these, there was correlation between location of stroke and severity of LVSD. However prospective randomized studies are needed to validate our results. Disclosure: Dr. Devulapalli has nothing to disclose. Dr. Dunlap has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Cockburn has nothing to disclose. Dr. Kurukumbi has nothing to disclose. Dr. Jayam-Trouth has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Devulapalli, S., Dunlap, S., Wilson, N., Cockburn, S., Kurukumbi, M., Jayam-Trouth, A. Tags: P02 Cerebrovascular Disease II Source Type: research