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Condition: Inflammatory Bowel Disease
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Total 222 results found since Jan 2013.
N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)
CONCLUSION: The use of N-acetylcysteine should be considered in a number of conditions as our population ages and levels of glutathione drop. Supplementation may contribute to reducing morbidity and mortality in some chronic conditions as outlined in the article.PMID:34221501 | PMC:PMC8211525 | DOI:10.1155/2021/9949453
Source: Journal of Nutrition and Metabolism - July 5, 2021 Category: Nutrition Authors: Gerry K Schwalfenberg Source Type: research
Pharmacological Inhibition of the Nod-Like Receptor Family Pyrin Domain Containing 3 Inflammasome with MCC950
Pharmacol Rev. 2021 Jul;73(3):968-1000. doi: 10.1124/pharmrev.120.000171.ABSTRACTActivation of the Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome drives release of the proinflammatory cytokines interleukin (IL)-1β and IL-18 and induces pyroptosis (lytic cell death). These events drive chronic inflammation, and as such, NLRP3 has been implicated in a large number of human diseases. These range from autoimmune conditions, the simplest of which is NLRP3 gain-of-function mutations leading to an orphan disease, cryopyrin-associated period syndrome, to large disease burden indications, such as atheroscl...
Source: Pharmacological Reviews - June 12, 2021 Category: Drugs & Pharmacology Authors: Sarah E Corcoran Reena Halai Matthew A Cooper Source Type: research
Increased risk of stroke among patients with inflammatory bowel disease: A PRISMA ‐compliant meta‐analysis
ConclusionIBD is a risk factor for stroke. More high-quality large-sample epidemiologic studies about the relationship between IBD and stroke should be further conducted.
Source: Brain and Behavior - May 7, 2021 Category: Neurology Authors: Yao Chen,
Xiang Wang Tags: REVIEW Source Type: research
Varicella zoster virus anterior uveitis complicated by thalamic stroke
We report a case of varicella zoster virus (VZV)-associated anterior uveitis in a patient with weight loss, arthritis and signs of inflammatory bowel disease. Her clinical course included the development of a thalamic stroke secondary to VZV cerebral vasculopathy. Following antiviral therapy, the patient ’s neurologic symptoms recovered and her ophthalmic findings improved.
Source: Journal of Ophthalmic Inflammation and Infection - May 1, 2021 Category: Opthalmology Source Type: research
Inflammatory Bowel Disease as a Precondition for Stroke or TIA: A Matter of Crohn's Disease Rather than Ulcerative Colitis
As a chronic systemic inflammation may be associated with an increased risk of vascular events, the aim of the present study was to assess the incidence of stroke and transient ischemic attack (TIA) in patients with inflammatory bowel disease over a period of 15 years.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2021 Category: Neurology Authors: Christian Tanislav, Kathleen Trommer, Christian Labenz, Karel Kostev Source Type: research
A journey through clinic and research
I started to study Medicine at the University of Genoa, Italy more than 20 years ago and I now realize that I was quite far from understanding what ‘Medicine’ really means. After weeks and weeks spent on books during the first year, I understood that becoming a MD not only requires the willingness to help people with health problems, but also strong motivation and dedication to learn a huge amount of notions. In Italy, as it is the case for several other countries, the University courses last 6 years, during which the MD student is fully engaged by individual study, lessons and seminars, exercises, and internships. Wit...
Source: European Heart Journal - March 29, 2021 Category: Cardiology Source Type: research
Successful Distancing: Telemedicine in Gastroenterology and Hepatology During the COVID-19 Pandemic
AbstractTelemedicine involves delivering healthcare and preventative care services to patients without the need for in-person encounters. Traditionally, telemedicine has been used for acute events (e.g., stroke, used to relay essential information to the emergency department) and chronic disease management (e.g., diabetes and chronic kidney disease management). Though the utilization of telemedicine in gastroenterology and hepatology has been modest at best, especially for inflammatory bowel diseases and chronic liver disease management, since the onset of coronavirus disease 2019 (COVID-19) pandemic, utilization of teleme...
Source: Digestive Diseases and Sciences - March 3, 2021 Category: Gastroenterology Source Type: research
Giant Vertebrobasilar Fusiform Aneurysm Mass Effect Heralds Rapid in Situ Thrombosis and Ischemic Stroke in the Setting of Ulcerative Colitis
Here we describe a case of brainstem infarction secondary to rapid thrombus formation in a giant vertebrobasilar fusiform aneurysm (GVBFA) that was preceded clinically by several months of headaches and dizziness initially attributable to mass effect. Less than a month after initial identification of the aneurysm, a large partially-occluding thrombus formed leading to infarction of the brainstem. Interestingly, this patient also had ulcerative colitis, which has been associated with acquired hypercoagulability.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2021 Category: Neurology Authors: Keith J. Kincaid, Ju Yu, Franklin D. Echevarria, Alexis N. Simpkins Tags: Case Report Source Type: research
Association Between Chronic Inflammatory Diseases and Stroke-Associated Pneumonia – An Epidemiological Study
This study assessed the relationship between chronic inflammatory diseases and stroke-associated pneumonia (SAP).
Source: Journal of Stroke and Cerebrovascular Diseases - January 19, 2021 Category: Neurology Authors: Layne Dylla, Paco S. Herson, Sharon N. Poisson, John D. Rice, Adit A. Ginde Source Type: research
