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Condition: Hemorrhagic Stroke
Therapy: Statin Therapy

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Total 361 results found since Jan 2013.

Long-Term Evolocumab in Patients with Established Atherosclerotic Cardiovascular Disease
CONCLUSIONS: Long-term LDL-C lowering with evolocumab was associated with persistently low rates of adverse events for over >8 years that did not exceed those observed in the original placebo arm during the parent study and led to further reductions in cardiovascular events compared with delayed treatment initiation.PMID:36031810 | DOI:10.1161/CIRCULATIONAHA.122.061620
Source: Circulation - August 29, 2022 Category: Cardiology Authors: Michelle L O'Donoghue Robert P Giugliano Stephen D Wiviott Dan Atar Anthony C Keech Julia F Kuder KyungAh Im Sabina A Murphy Jose H Flores-Arredondo J Antonio G Lopez Mary Elliott-Davey Bei Wang Maria Laura Monsalvo Siddique Abbasi Marc S Sabatine Source Type: research

Incidence of Statin-Associated Adverse Events in Kidney Transplant Recipients
CONCLUSIONS: Statins appear to be generally well-tolerated in kidney transplant recipients. However, statin use might be associated with slightly higher risk of post-transplant diabetes mellitus, cataract, and rhabdomyolysis.PMID:36800538 | DOI:10.2215/CJN.0000000000000124
Source: Clinical Journal of the American Society of Nephrology : CJASN - February 17, 2023 Category: Urology & Nephrology Authors: Sunjae Bae JiYoon B Ahn Kmd Corey Joseph Ryan Whisler Mark A Schnitzler Krista L Lentine Bernard S Kadosh Dorry L Segev Mara A McAdams-DeMarco Source Type: research

E-113 Lower low-density lipoprotein level increases the risk of delayed parenchymal hematoma following endovascular thrombectomy
ConclusionLDL level <50 mg/dL independently predicted delayed PH following thrombectomy and LDL >100 was shown to be a protective factor, irrespective of statin use. Further study is needed to explore the underlying mechanism and identify the strategies to prevent post-thrombectomy delayed PH among patients with low LDL levels.Disclosures S. Ahn: None. S. Roth: None. J. Jo: None. Y. Ko: None. N. Mummareddy: None. M. Fusco: None. R. Chitale: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ahn, S., Roth, S., Jo, J., Ko, Y., Mummareddy, N., Fusco, M., Chitale, R., Froehler, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Prognostic importance of atrial fibrillation in asymptomatic aortic stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis study
Conclusion: Rate of AF is moderate in asymptomatic AS. Longstanding but not episodic AF was, independently predictive of increased risk of heart failure and non-hemorrhagic stroke. New-onset AF was associated with cardiac decompensation.
Source: International Journal of Cardiology - October 13, 2011 Category: Cardiology Authors: Anders M. Greve, Eva Gerdts, Kurt Boman, Christa Gohlke-Baerwolf, Anne B. Rossebø, Christoph A. Nienaber, Simon Ray, Kenneth Egstrup, Terje R. Pedersen, Lars Køber, Ronnie Willenheimer, Kristian Wachtell Tags: Original Articles Source Type: research

Carotid endarterectomy for symptomatic low-grade carotid stenosis
Conclusions: This study shows that CEA is a safe, effective, and durable treatment for patients with symptomatic low-grade carotid stenosis associated with unstable plaque. Patients had excellent protection against further ischemic events and survived long enough to justify the initial surgical risk. Plaque instability seems to play a major part in the onset of ischemic events, regardless the entity of lumen narrowing.
Source: Journal of Vascular Surgery - August 19, 2013 Category: Surgery Authors: Enzo Ballotta, Annalisa Angelini, Franco Mazzalai, Giacomo Piatto, Antonio Toniato, Claudio Baracchini Tags: Clinical research studies Source Type: research

Cerebrovascular neurosurgery 2014
Publication date: Available online 14 February 2015 Source:Journal of Clinical Neuroscience Author(s): Mohamed Salem , Bradley A. Gross , Rose Du , Ajith J. Thomas Continued advances in our understanding of the management of cerebrovascular disease were made in 2014. A randomized trial for management of unruptured brain arteriovenous malformation (ARUBA) (Mohr et al. Lancet 2014;383:614–21.) and the Scottish intracranial vascular malformation study (Al-Shahi Salman et al. JAMA 2014;311:1661–9) were published and contrasted with reports based on extensive surgical experience. We highlight the results from the simvasta...
Source: Journal of Clinical Neuroscience - February 16, 2015 Category: Neuroscience Source Type: research

Dual Antiplatelet Therapy Prior to Expedited Carotid Surgery Reduces Recurrent Events Prior to Surgery without Significantly Increasing Peri-operative Bleeding Complications.
CONCLUSION: Early introduction of dual antiplatelet therapy was associated with a significant reduction in recurrent neurological events and spontaneous embolization prior to CEA, without incurring a significant increase in major peri-operative bleeding complications. PMID: 26283034 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 14, 2015 Category: Surgery Authors: Batchelder A, Hunter J, Cairns V, Sandford R, Munshi A, Naylor AR Tags: Eur J Vasc Endovasc Surg Source Type: research

Potential role of statins in the intracerebral hemorrhage and subarachnoid hemorrhage.
Abstract Statins are used in primary and secondary prevention of cardiovascular episodes. Most of recent studies regard ischemic stroke. There are more emerging results of studies suggesting usefulness of these drugs in the other types of stroke e.g. intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Searching for new methods of treatment is important, because both ICH and SAH lead to poor prognosis and severe psychomotor disability. The unquestionable role of inflammatory factors in the pathogenesis of these disorders justifies considering statin treatment. Previous results are contradictory, thus ...
Source: Neurologia i Neurochirurgia Polska - September 19, 2015 Category: Neurology Authors: Kotlęga D, Gołąb-Janowska M, Masztalewicz M, Ciećwież S, Nowacki P Tags: Neurol Neurochir Pol Source Type: research

Potential role of statins in the intracerebral hemorrhage and subarachnoid hemorrhage
Publication date: September–October 2015 Source:Neurologia i Neurochirurgia Polska, Volume 49, Issue 5 Author(s): Dariusz Kotlęga, Monika Gołąb-Janowska, Marta Masztalewicz, Sylwester Ciećwież, Przemysław Nowacki Statins are used in primary and secondary prevention of cardiovascular episodes. Most of recent studies regard ischemic stroke. There are more emerging results of studies suggesting usefulness of these drugs in the other types of stroke e.g. intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Searching for new methods of treatment is important, because both ICH and SAH lead to poor pro...
Source: Polish Journal of Neurology and Neurosurgery - January 19, 2016 Category: Neurosurgery Source Type: research

Blood lipid levels, statin therapy and the risk of intracerebral hemorrhage
Dyslipidemia has been proven to play an important role in the occurrence and development of the ischemic stroke and lipid-lowering therapy could significantly decrease the risk of the ischemic stroke. However,...
Source: Lipids in Health and Disease - March 1, 2016 Category: Lipidology Authors: Yingxu Ma, Zhaokai Li, Liang Chen and Xiangping Li Source Type: research