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Condition: Ischemic Stroke
Procedure: Transplants

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Total 1030 results found since Jan 2013.

Three-Year Experience of Kidney Transplantation at a Single Center in Uzbekistan
CONCLUSIONS: Delayed graft function developed when duration of warm ischemia was increased, which was influenced by the number of vessels in the donor kidney. This is an important prognostic factor for acute rejection development. The risk of vascular complications increases due to postoperative hemodialysis trough, with development of delayed graft function. Recipient deaths during the first year after kidney transplant were mainly from pulmonary embolism, infection, and sepsis as a result of immunosuppression, hypovolemic shock, and acute ischemic stroke.PMID:35384804 | DOI:10.6002/ect.MESOT2021.O10
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 6, 2022 Category: Transplant Surgery Authors: Abdukhakim Khadjibaev Farhod Khadjibaev Rano Rakhimova Visolat Sharipova Pulat Sultanov Dilshod Ergashev Khikmat Anvarov Malika Ruzibakieva Source Type: research

Central VA-ECMO Support without Full Anticoagulation is Feasible During Lung Transplant
In this study, we analyzed the feasibility of central VA-ECMO without full anticoagulation during lung transplantation. We also analyzed the incidence of morbidity including ischemic and thrombotic complications, stroke, and postoperative outcomes.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: Y. Yagi, A. Manerikar, A. Bharat, C. Kurihara Tags: (911) Source Type: research

Carotid Endarterectomy Prior to Ventricular Assist Device Placement in a Patient with Cardiogenic Shock
Atherosclerotic disease in the cervical vessels may be a contraindication for implantation of left ventricular assist devices (LVADs). The occurrence of ischemic stroke represents an obstacle to rehabilitation, and its incidence seems to be higher in this population. Carotid endarterectomy (CEA) is a preferable surgical treatment in patients with high bleeding risk. This case report suggests that CEA followed by implantation of LVADs can be feasible.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M.S. Lira, R.C. Dantas, D.d. Belfort, S.R. Furquim, C.A. Arag ão, B.R. Gomes, B.S. Biselli, S.M. Ferreira, E.A. Bocchi Tags: (558) Source Type: research

Dental Pulp Stem Cell Therapy in Ischemic Stroke: A Meta-Analysis of Preclinical Studies
More preclinical research evidence has shown that dental pulp stem cells (DPSCs) transplantation is expected to promote the recovery of ischemic stroke (IS), but it still lacks an evidence-based analysis. The purpose of this study was to investigate the effects of DPSCs on neurological function and infarct size in Sprague-Dawley (SD) rats with middle cerebral artery embolization (MCAO).
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2022 Category: Neurology Authors: Hongxia Wang, Mengjiao Sun, Jing Sun, Panpan Gong, Ning Liu, Manxia Wang Source Type: research

The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids
Cell Mol Neurobiol. 2022 Mar 28. doi: 10.1007/s10571-022-01209-4. Online ahead of print.ABSTRACTShort-chain fatty acids (SCFAs) are monocarboxylates produced by the gut microbiota (GM) and result from the interaction between diet and GM. An increasing number of studies about the microbiota-gut-brain axis (MGBA) indicated that SCFAs may be a crucial mediator in the MGBA, but their roles have not been fully clarified. In addition, there are few studies directly exploring the role of SCFAs as a potential regulator of microbial targeted interventions in ischemic stroke, especially for clinical studies. This review summarizes t...
Source: Cellular and Molecular Neurobiology - March 29, 2022 Category: Cytology Authors: Zongwei Fang Mingrong Chen Jiafen Qian Chunhua Wang Jinhua Zhang Source Type: research

Final Results of Allogeneic Adipose Tissue-Derived Mesenchymal Stem Cells in Acute Ischemic Stroke (AMASCIS): A Phase II, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Pilot Clinical Trial
We report the final trial results after 24 months of follow-up. Recruitment began in December 2014 and stopped in December 2017 after 19 of 20 planned patients were included. Six patients did not receive study treatment: two due to technical issues and four for acquiring exclusion criteria after randomization. The final study sample was composed of 13 patients (4 receiving AD-MSCs and 9 placebo). One patient in the placebo group died within the first week after study treatment delivery due to sepsis. Two non-treatment-related serious AEs occurred in the AD-MSC group and nine in the placebo group. The total number of AEs an...
Source: Cell Transplantation - March 18, 2022 Category: Cytology Authors: Elena de Celis-Ruiz Blanca Fuentes Mar ía Alonso de Leciñana Mar ía Gutiérrez-Fernández Alberto M Borobia Raquel Guti érrez-Zúñiga Gerardo Ruiz-Ares Laura Otero-Ortega Fernando Laso-Garc ía Mari Carmen G ómez-de Frutos Exuperio D íez-Tejedor Source Type: research

Development of Duramycin-Based Molecular Probes for Cell Death Imaging
Mol Imaging Biol. 2022 Feb 10. doi: 10.1007/s11307-022-01707-3. Online ahead of print.ABSTRACTCell death is involved in numerous pathological conditions such as cardiovascular disorders, ischemic stroke and organ transplant rejection, and plays a critical role in the treatment of cancer. Cell death imaging can serve as a noninvasive means to detect the severity of tissue damage, monitor the progression of diseases, and evaluate the effectiveness of treatments, which help to provide prognostic information and guide the formulation of individualized treatment plans. The high abundance of phosphatidylethanolamine (PE), which ...
Source: Mol Biol Cell - February 10, 2022 Category: Molecular Biology Authors: Dongjian Zhang Meng Gao Qiaomei Jin Yicheng Ni Huailiang Li Cuihua Jiang Jian Zhang Source Type: research

Controlled temperatures in cold preservation provides safe heart transplantation results
ConclusionUsing the SherpaPak system during heart transplantation is safe and not associated with significant recipient morbidity. None of the recipients experienced significant PGD and mortality.
Source: Journal of Cardiac Surgery - January 21, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Macit Bitargil, Osama Haddad, Si M. Pham, Rohan M. Goswami, Parag C. Patel, Samuel Jacob, Magdy M. El ‐Sayed Ahmed, Juan Carlos Leoni Moreno, Daniel S. Yip, Kevin Landolfo, Basar Sareyyupoglu Tags: ORIGINAL ARTICLE Source Type: research