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Condition: Anaphylactic Shock

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Can patients with oral allergy syndrome be at risk of anaphylaxis?
Purpose of review Oral allergy syndrome, also known as pollen-food syndrome (PFS), is a condition usually associated with adults and characterized by mild transient oropharyngeal symptoms. The purpose of this review is to determine whether systemic or anaphylactic reactions do occur and if so, who is affected and what are the triggers. Recent findings An increasing number of studies demonstrate that PFS occurs all age groups, and a significant number of affected adults do experience systemic and anaphylactic reactions. The upsurge in the adoption of vegan lifestyles, increase in consumption of fruits and vegetables in...
Source: Current Opinion in Allergy and Clinical Immunology - August 27, 2020 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research

Pregnancy and Hymenoptera venom allergy
Purpose of review To evaluate the indication to perform venom immunotherapy (VIT) during pregnancy considering the risks of adverse events during the build-up phase or the maintenance phase and analyzing specific articles and guidelines on VIT. Recent findings Only few studies treat this argument and literature only counts one recent study on the topic, whereas recent guidelines state the behavior to keep in pregnancy. Summary Hymenoptera venom allergy (HVA) affects about 7.5% of the European population. VIT is the only effective disease-modifying treatment for patients presenting anaphylactic reactions. VIT counts...
Source: Current Opinion in Allergy and Clinical Immunology - August 27, 2020 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research

4th Pediatric Allergy and Asthma Meeting (PAAM)
DISCUSSION SESSION 1: Food allergy (PD01 –PD05)PD01 Allergen-specific humoral and cellular responses in children who fail egg oral immunotherapy due to allergic reactionsMarta Vazquez-Ortiz, Mariona Pascal, Ana Maria Plaza, Manel JuanPD02 FoxP3 epigenetic features in children with cow milk allergyLorella Paparo, Rita Nocerino, Rosita Aitoro, Ilaria Langella, Antonio Amoroso, Alessia Amoroso, Carmen Di Scala, Roberto Berni CananiPD04 Combined milk and egg allergy in early childhood: let them eat cake?Santanu Maity, Giuseppina Rotiroti, Minal GandhiPD05 Introduction of complementary foods in relation to allergy and gut mic...
Source: Clinical and Translational Allergy - October 31, 2016 Category: Allergy & Immunology Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Position document IgE-mediated allergy to egg protein.
Abstract Egg is the food that most often causes allergy in young Spanish children, with an incidence of 2.4-2.6% in the first 2 years of life. The prevalence of sensitisation and allergy to egg is greater in children with allergy to cow's milk and in those suffering atopic dermatitis. The protein component from egg white is the cause of the allergic response in child. The major allergens in egg white are ovomucoid and ovalbumin. Most of the allergic reactions affect the skin, followed by gastrointestinal and respiratory systems. Egg allergy is one of the most common causes of severe anaphylaxis. The diagnosis of e...
Source: Allergologia et Immunopathologia - July 2, 2013 Category: Allergy & Immunology Authors: Martorell A, Alonso E, Boné J, Echeverría L, López MC, Martín F, Nevot S, Plaza AM, Food allergy committee of SEICAP Tags: Allergol Immunopathol (Madr) Source Type: research

A potential breakthrough for peanut allergy treatment
Peanut allergies are among the most rapidly growing food allergies in the United States. Millions of children are currently living with the condition, with new cases being diagnosed daily. (A recent study shows the number of reported peanut allergies tripled in just over a decade.) And because allergic reactions to peanuts tend to be the most severe—80 to 95 percent of all food allergy deaths are peanut or tree nut related—the trend is a serious cause for concern. But a small pilot study published by the Journal of Allergy and Clinical Immunology, may offer hope for the hundred of thousands of families living with the ...
Source: Thrive, Children's Hospital Boston - November 4, 2013 Category: Pediatrics Authors: Tripp Underwood Tags: All posts Food allergies Kids' safety Milk allergies Parenting clinical trial food allergy Dale Umetsu Lynda Schneider peanut allergies Rima Rachid Source Type: news

Position document: IgE-mediated cow's milk allergy.
y) Abstract The present document offers an update on the recommendations for managing patients with cow's milk allergy - a disorder that manifests in the first year of life, with an estimated prevalence of 1.6-3% in this paediatric age group. The main causal allergens are the caseins and proteins in lactoserum (beta-lactoglobulin, alpha-lactoalbumin), and the clinical manifestations are highly variable in terms of their presentation and severity. Most allergic reactions affect the skin, followed by the gastrointestinal and respiratory systems, and severe anaphylaxis may occur. The diagnosis of cow's milk allergy i...
Source: Allergologia et Immunopathologia - March 19, 2015 Category: Allergy & Immunology Authors: Martorell-Aragonés A, Echeverría-Zudaire L, Alonso-Lebrero E, Boné-Calvo J, Martín-Muñoz MF, Nevot-Falcó S, Piquer-Gibert M, Valdesoiro-Navarrete L, Food allergy committee of SEICAP (Spanish Society of Pediatric Allergy, Asthma and Clinical Immunolo Tags: Allergol Immunopathol (Madr) Source Type: research

Risk Factors for Hen’s Egg Allergy in Europe: EuroPrevall birth cohort
ConclusionsSimilar to peanut allergy, eczema was strongly associated with egg allergy development and the association increased with increasing eczema severity. The age of introduction of dietary egg was not a risk factor. The potential role of antibiotics in early life as a risk factor for egg allergy needs further examination.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 15, 2019 Category: Allergy & Immunology Source Type: research

Risk Factors for Hen's Egg Allergy in Europe: EuroPrevall Birth Cohort
ConclusionsSimilar to peanut allergy, eczema was strongly associated with egg allergy development and the association increased with increasing eczema severity. The age of introduction of dietary egg was not a risk factor. The potential role of antibiotics in early life as a risk factor for egg allergy needs further examination.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 29, 2019 Category: Allergy & Immunology Source Type: research

What affects quality of life among caregivers of food-allergic children?
CONCLUSION: Food allergen, having multiple food allergies, age at reaction, income, eczema, parent-reported anaphylaxis, and reaction perception can significantly affect caregiver food allergy QoL. Milk or egg allergy was associated with worse total and domain-specific caregiver QoL scores vs peanut or tree nut allergy, representing a high-risk subgroup. PMID: 24950845 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - June 26, 2014 Category: Allergy & Immunology Authors: Howe L, Franxman T, Teich E, Greenhawt M Tags: Ann Allergy Asthma Immunol Source Type: research

Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap
ConclusionsAn epidemiological relationship between wheat allergy and contact exposure to HWP has been documented. This study implicates a possible role of contact exposure to food‐derived protein hydrolysates as a risk factor for the development of food allergy manifesting itself as anaphylaxis.This article is protected by copyright. All rights reserved.
Source: Allergy - July 8, 2014 Category: Allergy & Immunology Authors: Yuma Fukutomi, Masami Taniguchi, Hiroyuki Nakamura, Kazuo Akiyama Tags: Original Article: Anaphylaxis Source Type: research

Use of a basophil activation test as a complementary diagnostic tool in the diagnosis of severe peanut allergy in adults
Conclusions BAT is useful in determining the severity of peanut allergy and may be used as a complementary diagnostic tool to ensure accurate diagnosis of severe peanut allergy in adults. Thus, it may reduce the need to subject these patients to further tests, including an open challenge with peanuts.
Source: Clinical and Translational Allergy - June 11, 2015 Category: Allergy & Immunology Source Type: research

Epidemiology of food allergy and food-induced anaphylaxis: is there really a Western world epidemic?
Purpose of review: Food-induced anaphylaxis continues to be an important cause of hospital admissions, particularly in children. This review outlines recent advances in understanding the epidemiology of IgE-mediated food allergy and potential mechanisms for its rise in prevalence. Recent findings: The rise in food allergy prevalence in Western countries has happened more quickly than changes to the genome can occur; thus, environmental changes are likely to be important. Recent studies, however, suggest that genetic risk determines responses to environmental risk factors. Environmental peanut exposure has been associated w...
Source: Current Opinion in Allergy and Clinical Immunology - August 29, 2015 Category: Allergy & Immunology Tags: GENETICS AND EPIDEMIOLOGY: Edited by Isabella Annesi-Maesano and Antonella Cianferoni Source Type: research

Cor a 14 is the superior serological marker for hazelnut allergy in children, independent of concomitant peanut allergy
ConclusionConcomitant peanut allergy is common in hazelnut allergic children, but decision points as well as diagnostic values for Cor a 14 are not affected. We found 3 independent and well‐characterized serotypes; hazelnut allergic children sensitized to Cor a 14, peanut allergic children sensitized to Ara h 2 and children sensitized to birch pollen protein Bet v 1.This article is protected by copyright. All rights reserved.
Source: Allergy - December 1, 2015 Category: Allergy & Immunology Authors: Esben Eller, Charlotte G Mortz, Carsten Bindslev‐Jensen Tags: Original Article: Anaphylaxis Source Type: research

Precision Medicine in Allergic Disease – Food Allergy, Drug Allergy, and Anaphylaxis‐PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology
This article is protected by copyright. All rights reserved.
Source: Allergy - January 24, 2017 Category: Allergy & Immunology Authors: Antonella Muraro, Robert F. Lemanske, Mariana Castells, Maria J. Torres, David Khan, Hans ‐Uwe Simon, Carsten Bindslev‐Jensen, Wesley Burks, Lars K. Poulsen, Hugh A. Sampson, Margitta Worm, Kari C. Nadeau Tags: Review Source Type: research