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Condition: Anaphylactic Shock

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Total 7645 results found since Jan 2013.

Eperisone-Induced Anaphylaxis: Pharmacovigilance Data and Results of Allergy Testing.
CONCLUSIONS: Incidence of eperisone-induced anaphylaxis calculated from the KIDS-KAERS database was 0.001%. Eperisone can cause hypersensitive reactions, including anaphylaxis, possibly by inducing non-immunoglobulin E-mediated immediate hypersensitivity. PMID: 30661315 [PubMed]
Source: Allergy, Asthma and Immunology Research - January 22, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine highly allergic volunteers using allergy alert test: the Italian experience.
Conclusion: Most SR during UR were mild with no need for adrenaline treatment. The honey bee venom and the severity of the anaphylaxis during the field sting were the only SR´s risk factors for systemic adverse reactions during the UR. PMID: 30702236 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 2, 2019 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Making the GRADE in Anaphylaxis Management: Towards Recommendations Integrating Values, Preferences, Context, and Shared Decision-Making.
CONCLUSION: Clinical guidelines provide an important opportunity to critically appraise evidence and translate evidence to practice. Patients, clinicians, and policy makers should appreciate the strength of recommendation and certainty of evidence, and understand how this impacts guideline applicability and implementation. PMID: 32199979 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 17, 2020 Category: Allergy & Immunology Authors: Shaker MS, Oppenheimer J, Wallace DV, Golden DBK, Lang DM, Joint Task Force for Allergy Practice Parameters, Lang ES, Bernstein JA, Campbell RL, Chu D, Dinakar C, Ellis AK, Greenhawt M, Horner C, Lieberman JA, Rank MA, Stukus DR, Wang J Tags: Ann Allergy Asthma Immunol Source Type: research

Predictors of Severe Anaphylaxis In Hymenoptera Venom Allergy: The Importance of Absence of Urticaria/Angioedema.
PMID: 32199978 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 17, 2020 Category: Allergy & Immunology Authors: Chapsa M, Roensch H, Langner M, Beissert S, Bauer A Tags: Ann Allergy Asthma Immunol Source Type: research

Natural history and long-term follow-up of Hymenoptera allergy
Purpose of review Information on the natural history of hypersensitivity reactions is helpful for deciding which patient urgently needs a venom immunotherapy (VIT). Recent findings The frequency of self-reported systemic allergic reactions (SAR) to Hymenoptera stings is approximately 3–7% in the Northern Hemisphere. About 25% of SAR are severe (anaphylactic shock). Fatal sting reactions are very rare. The most important risk factor for severe insect sting anaphylaxis is mast cell disease. Other risk factors are higher age, vespid venom allergy (in contrast to honeybee venom allergy), repeated stings, male sex, and t...
Source: Current Opinion in Allergy and Clinical Immunology - August 27, 2020 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research

Global patterns of drug allergy-induced fatalities: a wake-up call to prevent avoidable deaths
Purpose of review To identify patterns and key issues though a systematic review in order to support prevention strategies and reduce avoidable deaths related to drug-induced anaphylaxis (DAF). Recent findings DAF rate has been estimated by 0.13–0.53/106 population/year. General global trends of DAF are increasing over time, mostly occurring at healthcare settings (62%) with a similar gender distribution and an average age of 53 years. Antibiotics, anaesthetics, radio-contrast media and NSAIDs were the most frequently implicated agents. Main comorbidities were personal history of drug allergy, cardiovascul...
Source: Current Opinion in Allergy and Clinical Immunology - July 27, 2022 Category: Allergy & Immunology Tags: DRUG ALLERGY: Edited by Paul Whitaker and Luciana K. Tanno Source Type: research

Childhood Peanut Allergy Linked With Other Legume Allergies Childhood Peanut Allergy Linked With Other Legume Allergies
French children with peanut allergy also tend to have allergies to one or more other legumes, which are likely to cause anaphylactic reactions, researchers in France report.Medscape Medical News
Source: Medscape Allergy Headlines - October 4, 2022 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Strategies to Treat Food Allergy With Oral Immunotherapy Strategies to Treat Food Allergy With Oral Immunotherapy
Oral immunotherapy for food allergy can protect against anaphylaxis, but it rarely cures, has risks, and requires collaboration by patients, their families, and their allergists, researchers report.Medscape Medical News
Source: Medscape Allergy Headlines - October 28, 2022 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence
Filaggrin is an epidermal protein that has a role in skin barrier function. Filaggrin loss-of-function (FLG-LOF) mutations are a significant risk factor for eczema and atopy, but their association with food allergy (FA) is less clear.
Source: Journal of Allergy and Clinical Immunology - August 28, 2014 Category: Allergy & Immunology Authors: Devasmitha Venkataraman, Nelís Soto-Ramírez, Ramesh J. Kurukulaaratchy, John W. Holloway, Wilfried Karmaus, Susan L. Ewart, S. Hasan Arshad, Mich Erlewyn-Lajeunesse Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

A ‘difficult’ insect allergy patient: reliable history of a sting, but all testing negative
Purpose of review: Few conditions are as treatable as allergy to stinging insects, with venom immunotherapy (VIT) providing up to 98% protection to subsequent stings. The challenge with VIT is not in the treatment, but in the diagnosis. To offer VIT, one must determine a history of a systemic reaction to a stinging insect in conjunction with the presence venom-specific IgE. Current diagnostic methods, although sensitive and specific, are imperfect, and some newer testing options are not widely available. A conundrum occasionally faced is the patient with a reliable and compelling history of a systemic allergic reaction yet...
Source: Current Opinion in Allergy and Clinical Immunology - June 26, 2015 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Jeffrey G. Demain Source Type: research

Guidelines for the use and interpretation of diagnostic methods in adult food allergy
Food allergy has an increasing prevalence in the general population and in Italy concerns 8 % of people with allergies. The spectrum of its clinical manifestations ranges from mild symptoms up to potentially fatal anaphylactic shock. A number of patients can be diagnosed easily by the use of first- and second-level procedures (history, skin tests and allergen specific IgE). Patients with complex presentation, such as multiple sensitizations and pollen-food syndromes, frequently require a third-level approach including molecular diagnostics, which enables the design of a component-resolved sensitization profile for each pa...
Source: Clinical and Molecular Allergy - October 5, 2015 Category: Allergy & Immunology Authors: Donatella MacchiaGiovanni MelioliValerio PravettoniEleonora NuceraMarta PiantanidaMarco CaminatiCorrado CampochiaroMona-Rita YacoubDomenico SchiavinoRoberto PaganelliMario Di GioacchinoOn behalf of the Food Allergy Study Group (ATI) of the Italian Society Source Type: research

Doctor, my child is bullied: food allergy management in schools
Purpose of review: Studies suggest that food allergies have increased in prevalence, resulting in most school classrooms having more than one child affected. Children with food allergies are vulnerable for experiencing potentially life-threatening allergic reactions, as well as social consequences such as bullying. Management recommendations for food allergies in schools should incorporate knowledge of both issues. Recent findings: Current recommendations for food allergy management in schools focus on appropriate avoidance measures and prompt recognition and treatment of allergic reactions. Guidelines focus upon a school...
Source: Current Opinion in Allergy and Clinical Immunology - April 29, 2016 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Julie Wang Source Type: research

Guidance on Completing a Written Allergy and Anaphylaxis Emergency Plan
This report offers a comprehensive written plan, with advice on individualizing instructions to suit specific patient circumstances.
Source: PEDIATRICS - February 28, 2017 Category: Pediatrics Authors: Wang, J., Sicherer, S. H., SECTION ON ALLERGY AND IMMUNOLOGY Tags: Allergy/Immunology From the American Academy of Pediatrics Source Type: research

Omalizumab facilitates rapid oral desensitization for peanut allergy
Peanut oral immunotherapy is a promising approach to peanut allergy, but reactions are frequent, and some patients cannot be desensitized. The anti-IgE medication omalizumab (Xolair; Genentech, South San Francisco, Calif) might allow more rapid peanut updosing and decrease reactions.
Source: Journal of Allergy and Clinical Immunology - September 5, 2016 Category: Allergy & Immunology Authors: Andrew J. MacGinnitie, Rima Rachid, Hana Gragg, Sara V. Little, Paul Lakin, Antonella Cianferoni, Jennifer Heimall, Melanie Makhija, Rachel Robison, R. Sharon Chinthrajah, John Lee, Jennifer Lebovidge, Tina Dominguez, Courtney Rooney, Megan Ott Lewis, Jen Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Skin inflammation exacerbates food allergy symptoms in epicutaneously sensitized mice
ConclusionEven after eliminating exposure to the antigen, inflammation from skin barrier disruption can exacerbate the severity of food allergy symptoms. Serum baseline mmcp1 levels might be an effective marker for predicting the severity of antigen‐induced allergic symptoms.This article is protected by copyright. All rights reserved.
Source: Allergy - January 10, 2018 Category: Allergy & Immunology Authors: Akiko Kawasaki, Naohiro Ito, Hiroki Murai, Motoko Yasutomi, Hironobu Naiki, Yusei Ohshima Tags: Original Article: Experimental Allergy and Immunology Source Type: research