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Condition: SARS
Infectious Disease: Pandemics

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Total 689 results found since Jan 2013.

Cardiovascular Complications in Coronavirus Disease 2019-Pathogenesis and Management
Semin Respir Crit Care Med. 2023 Feb;44(1):21-34. doi: 10.1055/s-0042-1760096. Epub 2023 Jan 16.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic has caused a devastating impact on morbidity and mortality around the world. Severe acute respiratory syndrome-coronavirus-2 has a characteristic tropism for the cardiovascular system by entering the host cells and binding to angiotensin-converting enzyme 2 receptors, which are expressed in different cells, particularly endothelial cells. This endothelial injury is linked by a direct intracellular viral invasion leading to inflammation, microthrombosis, and angiogenesis. C...
Source: Respiratory Care - January 16, 2023 Category: Respiratory Medicine Authors: Marcos I Restrepo Judith Marin-Corral Juan J Rodriguez Valeria Restrepo Rodrigo Cavallazzi Source Type: research

Cardiovascular Complications in Coronavirus Disease 2019 —Pathogenesis and Management
Semin Respir Crit Care Med 2023; 44: 021-034 DOI: 10.1055/s-0042-1760096The coronavirus disease 2019 (COVID-19) pandemic has caused a devastating impact on morbidity and mortality around the world. Severe acute respiratory syndrome-coronavirus-2 has a characteristic tropism for the cardiovascular system by entering the host cells and binding to angiotensin-converting enzyme 2 receptors, which are expressed in different cells, particularly endothelial cells. This endothelial injury is linked by a direct intracellular viral invasion leading to inflammation, microthrombosis, and angiogenesis. COVID-19 has been associated with...
Source: Seminars in Respiratory and Critical Care Medicine - January 16, 2023 Category: Respiratory Medicine Authors: Restrepo, Marcos I. Marin-Corral, Judith Rodriguez, Juan J. Restrepo, Valeria Cavallazzi, Rodrigo Tags: Review Article Source Type: research

Original Article: Increased Stroke Severity and Mortality in Patients with SARS-CoV-2 Infection: An Analysis from the N3C Database
Studies from early in the COVID-19 pandemic showed that patients with ischemic stroke and concurrent SARS-CoV-2 infection had increased stroke severity. We aimed to test the hypothesis that this association persisted throughout the first year of the pandemic and that a similar increase in stroke severity was present in patients with hemorrhagic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Jackson A Narrett, Indika Mallawaarachchi, Chad M. Aldridge, Ethan D Assefa, Arti Patel, Johanna J Loomba, Sarah Ratcliffe, Ofer Sadan, Teshamae Monteith, Bradford B Worrall, Donald E Brown, Karen C Johnston, Andrew M Southerland, N3C consortium Source Type: research

Increased stroke severity and mortality in patients with SARS-CoV-2 infection: An analysis from the N3C database
Studies from early in the COVID-19 pandemic showed that patients with ischemic stroke and concurrent SARS-CoV-2 infection had increased stroke severity. We aimed to test the hypothesis that this association persisted throughout the first year of the pandemic and that a similar increase in stroke severity was present in patients with hemorrhagic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Jackson A Narrett, Indika Mallawaarachchi, Chad M. Aldridge, Ethan D Assefa, Arti Patel, Johanna J Loomba, Sarah Ratcliffe, Ofer Sadan, Teshamae Monteith, Bradford B Worrall, Donald E Brown, Karen C Johnston, Andrew M Southerland, N3C consortium Source Type: research

Telemedicine During COVID-19 Pandemic: Lesson Learned from the Lazio Region Infectious Diseases and Emergency Department Network
We describe the teleconsultation (TC) model in the Lazio Region. It uses a hub-and-spoke network system on geographic regional basis using a web based digital platform, termed ADVICE with the aim to connect regional Emergency Departments (EDs) and Infectious Diseases (ID) acute and critical care settings for patients with acute ID syndrome. Between January 2020 and June 2021, the ADVICE platform received 18.686 TCs: of them, 10838 requests (58%) were for ID TCs in 7996 patients, followed by 2555(13%) requests for trauma, 2286(12%) for acute complex syndrome and 1681 (8%) for Stroke TCs. Three quarter of ID TCs were request...
Source: Journal of Medical Systems - December 7, 2022 Category: Information Technology Source Type: research

Neurological manifestations in COVID-19 in three waves of the pandemic: An inpatient study from India
Conclusion: SARS-CoV-2 produces many central and peripheral nervous system manifestations. Encephalopathy was more common in first wave while acute symptomatic seizures were more common in third wave. Encephalopathy was most common neurological manifestation with progressively higher mortality with increased number of systemic comorbidities. Ischemic stroke was seen in patients who had vascular risk factors as well as in patients without them.
Source: Annals of Indian Academy of Neurology - December 3, 2022 Category: Neurology Authors: Rahul Kulkarni Dulari Gupta Shripad Pujari Vishal Deshpande Pravin Naphade Rushikesh Deshpande Source Type: research

Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their pathogenesis and clinical manifestations in the case of COVID-19. The risk factors, mechanisms of development, diagnostic approach, and the age characteristics of patients with neurological complications of COVID-19 are discussed. The specific mechanisms of the neuroinvasiveness and neurovirulence of the SARS-CoV-2 virus, regardless of the age of patients and the presence of risk factors, lead to systemic damage to the endothelium of small-caliber vessels, generalized thrombov...
Source: Advances in Gerontology - December 1, 2022 Category: Geriatrics Source Type: research

Mechanisms of COVID-19-induced cerebellitis
Curr Med Res Opin. 2022 Oct 28:1-25. doi: 10.1080/03007995.2022.2141963. Online ahead of print.ABSTRACTThe COVID-19 pandemic caused by SARS-CoV2 has raised several important health concerns, not least increased mortality and morbidity. SARS-CoV2 can infect the central nervous system via hematogenous or transneuronal routes, acting through different receptors including ACE2, DPP4 and neuropilin 1- and cause several issues, include the focus here, cerebellitis. The cerebellum is an essential part of the CNS located adjacent to the brainstem with a complex micro and macroscopic structure. The cerebellum plays several physiolo...
Source: Current Medical Research and Opinion - October 28, 2022 Category: Research Authors: Mohammad Banazadeh Sepehr Olangian-Tehrani Melika Sharifi Mohammadreza Malek-Ahmadi Farhad Nikzad Nooria Doozandeh-Nargesi Alireza Mohammadi Gary J Stephens Mohammad Shabani Source Type: research

Hereditary thrombotic thrombocytopenic purpura and COVID-19: Impacts of vaccination and infection in this rare disease
DISCUSSION: The risk of an acute episode triggered by COVID-19 seems higher than following vaccination in hTTP patients, who can be safely vaccinated against SARS-CoV-2.PMID:36284639 | PMC:PMC9585384 | DOI:10.1002/rth2.12814
Source: Thrombosis and Haemostasis - October 26, 2022 Category: Hematology Authors: Erika Tarasco Anne Sophie von Krogh Radomira Hrdlickova Thomas R Braschler Teresa Iwaniec Paul N Kn öbl Eriko Hamada Oleg Pikovsky Stefan Farese Odit Gutwein Petr Kessler Nina H Schultz Charis von Auer Jerzy Windyga Kenneth Friedman Ingrid Hrachovinova J Source Type: research

The COVID-19 pandemic effect on the prehospital Madrid stroke code metrics and diagnostic accuracy
by Nicol ás Riera-López, Andrea Gaetano-Gil, José Martínez-Gómez, Nuria Rodríguez-Rodil, Borja M. Fernández-Félix, Jorge Rodríguez-Pardo, Carmen Cuadrado-Hernández, Emmanuel Pelayo Martínez-González, Alicia Villar-Arias, Fátima Gutiérrez-Sánchez, Pablo Busca-Ostolaza, Eduardo Montero-Ruiz, Exu perio Díez-Tejedor, Javier Zamora, Blanca Fuentes-Gimeno, on behalf of the Madrid Stroke Network BackgroundOnly very few studies have investigated the effect of the COVID-19 pandemic on the pre-hospital stroke code protocol. During the first wave, Spain was one of the most affected countries by the SARS-CoV-2 coronavi...
Source: PLoS One - October 10, 2022 Category: Biomedical Science Authors: Nicol ás Riera-López Source Type: research

The impact of first wave of the SARS-CoV-2 2019 pandemic in Poland on characteristics and outcomes of patients hospitalized due to stable coronary artery disease
CONCLUSIONS: The SARS-CoV-2 2019 pandemic affected the characteristics and hospitalization course of stable angina patients hospitalized following the first wave. The hospitalization outcome was similar in the analyzed time intervals. The higher prevalence of comorbidities raises concern regarding upcoming years.PMID:36200545 | DOI:10.5603/CJ.a2022.0094
Source: Cardiology Journal - October 6, 2022 Category: Cardiology Authors: Justyna Jankowska-Sanetra Krzysztof Sanetra Marta Konopko Monika Kutowicz Magdalena Synak Krzysztof Milewski Pawe ł Kaźmierczak Łukasz Kołtowski Piotr P Buszman Source Type: research