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Bibliometric analysis of the worldwide scientific production on COVID-19 infection and cerebrovascular disease
CONCLUSION: It was observed that the United States was the country with the highest scientific production on COVID-19 and cerebrovascular disease in the year 2020 in the different health areas; however, more research is still needed worldwide for a better analysis of the bibliometric indicators on the subject.PMID:37706386 | PMC:PMC10284493 | DOI:10.4103/aca.aca_70_22
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Camila Palomino-Leyva Jhonny Rivera-Recuenco Alicia Fernandez-Giusti John Barja-Ore Yesenia Retamozo-Siancas Frank Mayta-Tovalino Source Type: research

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

Epidemiologic and Genomic Analysis of the Severe Acute Respiratory Syndrome Coronavirus 2 Epidemic in the Nebraska Region of the United States, March 2020 –2021
This report details the epidemiologic and genetic evolution of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first year of the epidemic in the state of Nebraska using data collected from the Creighton Catholic Health Initiatives (CHI) health system. Statistical modelling identified age, gender, and previous history of diabetes and/or stroke as significant risk factors associated with mortality in COVID-19 patients. In parallel, the viral genomes of over 1,000 samples were sequenced. The overall rate of viral variation in the population was 0.07 mutations/day. Genetically, the first 9 months of...
Source: Frontiers in Microbiology - May 18, 2022 Category: Microbiology Source Type: research

Identification of Novel Gene Signatures using Next-Generation Sequencing Data from COVID-19 Infection Models: Focus on Neuro-COVID and Potential Therapeutics
In conclusion, our study unravels a rapid approach for applying next-generation knowledge discovery (NGKD) platforms to discover small molecules with therapeutic potential against COVID-19 and its related disease pathologies.
Source: Frontiers in Pharmacology - August 31, 2021 Category: Drugs & Pharmacology Source Type: research

UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news

Malignant Cerebral Ischemia in A COVID-19 Infected Patient: Case Review and Histopathological Findings
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is responsible for an unprecedented worldwide pandemic that has severely impacted the United States. As the pandemic continues, a growing body of evidence suggests that infected patients may develop significant coagulopathy with resultant thromboembolic complications including deep vein thrombosis, pulmonary embolism, myocardial infarction, and ischemic stroke. However, this data is limited and comes from recent small case series and observational studies on stroke types, mechanisms, and outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2020 Category: Neurology Authors: Smit D. Patel, Ryan Kollar, Patrick Troy, Xianyuan Song, Mohammad Khaled, Augusto Parra, Mubashir Pervez Source Type: research

In defense of our patients: indirect negative neurological consequences of sars-cov-2 in the new york epicenter
New York has become the epicenter in the United States for the coronavirus disease 2019 (COVID-19) pandemic with approximately 202,829 infected, 52,697 hospitalized, and 17,055 confirmed deaths as of June 5, 2020.15 The large influx of critically ill patients resulted in widespread policy and practice changes to counter this new resource-limited setting. All elective surgeries were cancelled. Urgent cases required approval and were limited significantly, resulting in primarily emergency cases.
Source: Journal of Stroke and Cerebrovascular Diseases - July 9, 2020 Category: Neurology Authors: Jared B. Cooper, Anubhav G. Amin, Michael G. Kim, Alan A. Stein, Jose Dominguez, Krishna Amuluru, Rachana Tyagi, Stephan Mayer, Chirag D. Gandhi, Fawaz Al-Mufti Source Type: research

Potential Indirect Effects of the COVID-19 Pandemic on Use of Emergency Departments for Acute Life-Threatening Conditions - United States, January-May 2020.
This report describes trends in ED visits for three acute life-threatening health conditions (myocardial infarction [MI, also known as heart attack], stroke, and hyperglycemic crisis), immediately before and after declaration of the COVID-19 pandemic as a national emergency. These conditions represent acute events that always necessitate immediate emergency care, even during a public health emergency such as the COVID-19 pandemic. In the 10 weeks following the emergency declaration (March 15-May 23, 2020), ED visits declined 23% for MI, 20% for stroke, and 10% for hyperglycemic crisis, compared with the preceding 10-week p...
Source: MMWR Morb Mortal Wkl... - June 25, 2020 Category: Epidemiology Authors: Lange SJ, Ritchey MD, Goodman AB, Dias T, Twentyman E, Fuld J, Schieve LA, Imperatore G, Benoit SR, Kite-Powell A, Stein Z, Peacock G, Dowling NF, Briss PA, Hacker K, Gundlapalli AV, Yang Q Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Severe acute respiratory syndrome coronavirus 2 is penetrating to dementia research.
Abstract 1. Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus infectious disease 2019 (COVID-19), which was first reported in Wuhan, China, in late December, 2019. Despite the tremendous efforts to control the disease, SARS-CoV-2 has infected 1,5 million people and caused the death of more than a hundred thousand people across the globe as of writing. Recently, Mao et al. [1] investigated the penetration potential of SARS-CoV-2 into the central nervous system in 214 patients. They reported that 36.4% of the patients had some neurologic findings which are ranged from nonsp...
Source: Current Neurovascular Research - May 21, 2020 Category: Neurology Authors: Bostanciklioglu M, Temiz E Tags: Curr Neurovasc Res Source Type: research