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Total 140 results found since Jan 2013.

Title: Beyond Malnutrition: The Role of Sanitation in Stunted Growth
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine. Background image: WHO About This Article open Citation: Schmidt CW. 2014. Beyond malnutrition: the role of sanitation in stunted growth. Environ Health Perspect 122:A298–A303; http://dx.doi.org/10.1289/ehp.122-A298 News Topics: Children’s Health, Diet and Nutrition, Gastrointestinal Health, International Environmental Health, Microbial Agents, Musculoskeletal Health, Drinking Water Quality, Sanitation Published: 1 November 2014 PDF Version (2.8 MB) Worldwide, stuntin...
Source: EHP Research - October 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Children's Health Diet and Nutrition Drinking Water Quality Gastrointestinal Health International Environmental Health Microbial Agents Musculoskeletal Health November 2014 Sanitation Source Type: research

Elevated Serum Mannose-Binding Lectin Levels Are Associated with Poor Outcome After Acute Ischemic Stroke in Patients with Type 2 Diabetes
Abstract The activation of the complement system may be involved in the pathology of stroke and type 2 diabetes (T2DM). We therefore evaluated the long-term prognostic value of early measurement of serum mannose-binding lectin (MBL) levels, an activator of the complement system, in Chinese T2DM with acute ischemic stroke (AIS). Serum MBL levels were determined in T2DM patients with AIS (N = 188). The adjudicated end points were 1-year functional outcomes and mortality. The prognostic value of MBL was compared with the National Institutes of Health Stroke Scale score and with other known outcome predictors. Pat...
Source: Molecular Neurobiology - October 25, 2014 Category: Neurology Source Type: research

Watch less TV to prevent obesity, says NICE
“Take TV-free days to combat obesity, health experts urge,” The Guardian reports. This is one of a range of new recommendations from National Institute of Health and Care Excellence (NICE) draft guidelines that are designed to help adults and children maintain a healthy weight.Although the headlines have largely focused on TV (as well as other types of screen time, such as smartphones), the recommendations cover a range of health-related behaviours, such as walking to work and avoiding fizzy drinks.This draft guidance is mainly aimed at people in organisations who set up, pay for, or put into practice programmes that ...
Source: NHS News Feed - September 23, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Food/diet Obesity Source Type: news

Chelation therapy after the Trial to Assess Chelation Therapy: results of a unique trial
Purpose of reviewEDTA chelation therapy has been in off-label use for the treatment of atherosclerosis. We review the results of the first large-scale randomized trial of this treatment. Recent findingsThe trial to assess chelation therapy was a $30 million National Institutes of Health-funded study of the safety and efficacy of EDTA-based chelation infusions in 1708 post-myocardial infarction (MI) patients. The trial to assess chelation therapy demonstrated a significant (P = 0.035) 18% reduction in a combined primary endpoint of death, MI, stroke, coronary revascularization, or hospitalization for angina. In diabetic...
Source: Current Opinion in Cardiology - August 7, 2014 Category: Cardiology Tags: PREVENTION: Edited by Andrew Pipe Source Type: research

Infarction in the Anterior Choroidal Artery Territory: Clinical Progression and Prognosis Factors
This study was undertaken to describe the still poorly known evolving profile of anterior choroidal artery (AChA) infarctions, identify their prognosis factors, and evaluate responses to intravenous (IV) thrombolysis. During 42 months, we prospectively enrolled patients with an isolated AChA stroke. Clinical and radiologic parameters were compared between patients with or without progression, defined as any clinical worsening. Factors associated with poor outcome (dependence or death) were tested, and IV thrombolysis responses were assessed. For the 100 of 1234 (8.1%) analyzed patients with AChA stroke (predominantly lacu...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Nicolas Chausson, Julien Joux, Martine Saint-Vil, Mireille Edimonana, Séverine Jeannin, Mathieu Aveillan, Philippe Cabre, Stéphane Olindo, Didier Smadja Tags: Original Articles Source Type: research

Cynthia A. Bens - Elder Americans
One of the great achievements of the last 100 years has been the significant increase in the lifespan of Americans.  By 2050 it is estimated that 20 percent of the total U.S. population will be over the age of 65.  While this is something to celebrate, there is also a downside. With the expected growth of the aging population, we expect to see a significant rise in many chronic diseases where age is a major risk factor. The effects age-related chronic disease are immense both to the person experiencing them and society. Diseases like Alzheimer’s disease, frailty, diabetes, cardiovascular disease and stroke contribute t...
Source: PHRMA - June 17, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Cynthia A. Bens - Older Americans
One of the great achievements of the last 100 years has been the significant increase in the lifespan of Americans.  By 2050 it is estimated that 20 percent of the total U.S. population will be over the age of 65.  While this is something to celebrate, there is also a downside. With the expected growth of the aging population, we expect to see a significant rise in many chronic diseases where age is a major risk factor. The effects age-related chronic disease are immense both to the person experiencing them and society. Diseases like Alzheimer’s disease, frailty, diabetes, cardiovascular disease and stroke contribute t...
Source: PHRMA - June 17, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Cynthia A. Bens
Vice President, Public PolicyCynthia Bens is the Vice President of Public Policy at the not-for-profit Alliance for Aging Research in Washington, D.C.  In this capacity, Ms. Bens is responsible for guiding the organization’s federal policy work, representing the Alliance in multiple national coalitions, and directing all aspects of the Accelerate Cure/Treatments for Alzheimer’s Disease (ACT-AD) and Aging in Motion (AIM) coalitions. Ms. Bens sits on the Alliance for a Stronger FDA Board of Directors and is a Founding Executive Committee Member of Friends of the National Institute on Aging (FoNIA). She has served on the...
Source: PHRMA - June 17, 2014 Category: Pharmaceuticals Authors: Sabrina Source Type: news

Today's statin users consume more calories and fat, and weigh more, than their predecessors
People who take statin drugs to lower their cholesterol appear to have developed a false sense of security that could lead to heart disease and other obesity-related illnesses. A new UCLA-led study suggests that people who took statins in the 2009–10 year were consuming more calories and fat than those who used statins 10 years earlier. There was no similar increase in caloric and fat intake among non–stain users during that decade, researchers said. In 1999–2000, statin users were consuming fewer calories and less fat than individuals who didn't take these medications, but that is no longer the case. Increase...
Source: UCLA Newsroom: Health Sciences - April 25, 2014 Category: Universities & Medical Training Source Type: news

The Look AHEAD Study: Implications for Clinical Practice Go Beyond the Headlines
On Friday, October 19, 2012, the National Institutes of Health (NIH) announced that the lifestyle “intervention was stopped early in NIH-funded study of weight loss in overweight and obese adults with type 2 diabetes after finding no harm, but no cardiovascular benefits.” The primary study question of the long-term Look AHEAD (Action for Health in Diabetes) Study had been answered. An intensive lifestyle intervention program aimed at a 10% weight loss and 175 minutes of physical activity per week did not reduce cardiovascular events (defined as heart attack, stroke, hospitalization for angina, or death) in people with ...
Source: Journal of the American Dietetic Association - March 21, 2014 Category: Nutrition Authors: Linda M. Delahanty Tags: Commentary Source Type: research

Gynecologic Surgery in the Obese Patient
Obesity is a chronic multifactorial disease that presents serious health risks due to excessive fat accumulation in adipose tissue . Determinants such as genetics, psychosocial factors, the environment, poor diet, and physical inactivity all have a role in its development. Obesity was defined in 1998 by the National Institutes of Health clinical guidelines as body mass index (BMI) ≥30 . Obese individuals are at higher risk for many comorbid conditions and for overall mortality than are non-obese individuals. Some of these conditions include type 2 diabetes mellitus, hypertension, coronary artery disease, stroke, obstruc...
Source: The Journal of Minimally Invasive Gynecology - January 23, 2014 Category: OBGYN Authors: Karen Cooper, Tommaso Falcone Tags: Editorial Source Type: research

Current status of acute stroke management in Korea: a report on a multicenter, comprehensive acute stroke registry
There are limited data on the utilization of diagnostics and the variation of treatments at the national level in acute stroke care. Clinical Research Center for Stroke – 5th division stroke registry aimed to describe stroke statistics and quality of care in Korea and to implement quality indicators. Clinical Research Center for Stroke – 5th division registry was established in April 2008 and covers pretreatment demographics, medical and stroke severity measures, diagnostic evaluation, hyperacute revascularization, in‐hospital management, discharge disposition, quality indicators, and long‐term functional outcomes....
Source: International Journal of Stroke - November 21, 2013 Category: Neurology Authors: Beom Joon Kim, Moon‐Ku Han, Tai Hwan Park, Sang‐Soon Park, Kyung Bok Lee, Byung‐Chul Lee, Kyung‐Ho Yu, Jae Kwan Cha, Dae‐Hyun Kim, Jun Lee, Soo Joo Lee, Youngchai Ko, Jong‐Moo Park, Kyusik Kang, Yong‐Jin Cho, Keun‐Sik Hong, Ki‐Hyun Cho, Tags: Panorama Source Type: research

Brain Natriuretic Peptide in Acute Ischemic Stroke
Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic stroke. We measured serum BNP levels in consecutive patients aged 18 years or older. Stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment criteria. Categorical variables included age, sex, smoking status, alcohol consumption status, hypertension, diabetes mellitus, dyslipidemia...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Kenji Maruyama, Tsuyoshi Shiga, Mutsumi Iijima, Saori Moriya, Satoko Mizuno, Sono Toi, Kotaro Arai, Kyomi Ashihara, Kayoko Abe, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Prospective Study of Ultraviolet Radiation Exposure and Mortality Risk in the United States.
Abstract Geographic variations in mortality rate in the United States could be due to several hypothesized factors, one of which is exposure to solar ultraviolet radiation (UVR). Limited evidence from previous prospective studies has been inconclusive. The association between ambient residential UVR exposure and total and cause-specific mortality risks in a regionally diverse cohort (346,615 white, non-Hispanic subjects, 50-71 years of age, in the National Institutes of Health (NIH)-AARP Diet and Health Study) was assessed, with accounting for individual-level confounders. UVR exposure (averaged for 1978-1993 and ...
Source: Am J Epidemiol - July 17, 2013 Category: Epidemiology Authors: Lin SW, Wheeler DC, Park Y, Spriggs M, Hollenbeck AR, Freedman DM, Abnet CC Tags: Am J Epidemiol Source Type: research

Stroke severity and outcomes for octogenarians receiving statins
Abstract: Pre-exposure to 3-hydroxy-3-methylgutaryl-coenzyne A reductase inhibitors (statins) appears to improve outcomes in patients with acute ischemic stroke (AIS). Whether this extends to patients over 80 is not known. Patients ≥80 years of age with AIS were retrospectively reviewed from the stroke registry of a tertiary stroke center. Pre-admission statin use, demographics, vascular risk factors, and comorbid conditions were assessed. Primary outcomes were admission National Institutes of Health Stroke Scale (NIHSS) scores and in-hospital mortality/discharge to hospice, and secondary outcomes included subsequent int...
Source: Archives of Gerontology and Geriatrics - July 1, 2013 Category: Geriatrics Authors: Michael S. Phipps, Neer Zeevi, Ilene Staff, Gil Fortunato, George A. Kuchel, Louise D. McCullough Source Type: research