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Condition: Diabetes
Countries: Japan Health
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Total 325 results found since Jan 2013.
Janssen Data at ASCO GU Demonstrate Longstanding Leadership in Prostate Cancer and Commitment to Advancing Potential New Therapeutic Options for Genitourinary Cancers
Raritan, NJ, Feb. 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that 17 presentations will be featured at the 2022 American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium, taking place in San Francisco and virtually from February 17-19. Building on its long-term leadership in prostate cancer, Janssen is committed to advancing innovative treatments and transforming patient experiences, while focusing on research that may drive better outcomes for people across the genitourinary cancer spectrum. Data to be presented include Phase 3 results for the selective ...
Source: Johnson and Johnson - February 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Association between Dietary Manganese Intake and Mortality from Cardiovascular Disease in Japanese Population: The Japan Collaborative Cohort Study
CONCLUSIONS: Our study is the first to show the prospective association between dietary Mn intake and reduced risk of mortality from CVD in the Japanese population.PMID:35082202 | DOI:10.5551/jat.63195
Source: Journal of Atherosclerosis and Thrombosis - January 27, 2022 Category: Cardiology Authors: Ouyang Meishuo Ehab S Eshak Isao Muraki Renzhe Cui Kokoro Shirai Hiroyasu Iso Akiko Tamakoshi Source Type: research
Impact of cerebrovascular comorbidity on prognosis in Japanese patients undergoing PCI: 1-year data from Japanese multicenter registry (KICS)
This study ’s objective is to assess the impact of stroke on the prognosis of patients with underlying IHD, who underwent PCI treatment. This was a multicenter, 1-year observational study in patients undergoing PCI in one of the 17 participating centers across Japan. 18,495 patients were registered on the PC I list; 2481 patients had a prior stroke experience, whereas 15,979 were stroke-free. Our study revealed that stroke patients were significantly older (mean age 73.5 ± 9.6, 69.7(± 11.5), respectively), and suffered from more comorbidities (diabetes, hypertension, and chronic kidney disease,p < 0.0001)...
Source: Heart and Vessels - January 11, 2022 Category: Cardiology Source Type: research
Manifestation of Heart Failure and Chronic Kidney Disease are Associated with Increased Mortality Risk in Early Stages of Type 2 Diabetes Mellitus: Analysis of a Japanese Real-World Hospital Claims Database
ConclusionsThe high incidence of CKD or HF manifestation can contribute to the augmented mortality risk in patients in the early stages of T2DM compared with patients without T2DM. These findings highlight the importance of early interventions for preventing/treating CKD and HF to improve the prognosis of patients with T2DM.
Source: Diabetes Therapy - January 10, 2022 Category: Endocrinology Source Type: research
Clinical outcomes for intracoronary imaging strategies at different medical facilities in Japanese patients with coronary artery disease: the SAKURA imaging PCI Registry
AbstractThe relationships between intracoronary imaging modalities and outcomes among Japanese patients with coronary artery disease (CAD) based on the type of medical facility providing outpatient care remain unclear. In this multicenter prospective study (SAKURA PCI Registry), we aimed to investigate the clinical outcomes of patients with CAD who underwent percutaneous coronary intervention (PCI) between April 2015 and December 2018. In this registry, we investigated differences in patient characteristics, intracoronary imaging modalities, and clinical outcomes between two types of medical facilities. Of the 414 patients...
Source: Heart and Vessels - January 1, 2022 Category: Cardiology Source Type: research
Developing a Stroke Risk Prediction Model Using Cardiovascular Risk Factors: The Suita Study
Conclusion: We developed a new stroke risk model for the urban general population in Japan. Further research to determine the clinical practicality of this model is required.Cerebrovasc Dis
Source: Cerebrovascular Diseases - November 29, 2021 Category: Neurology Source Type: research
Determining whether periodic health checkups have any preventive effect on deterioration in health among middle-aged adults: A hazards model analysis in Japan
CONCLUSIONS: The preventive impact of PHCs on health deterioration is generally limited among middle-aged adults. Future studies should address policy measures to enhance the effectiveness of PHCs.PMID:34762338 | DOI:10.1002/1348-9585.12291
Source: Journal of Occupational Health - November 11, 2021 Category: Occupational Health Authors: Takashi Oshio Akizumi Tsutsumi Akiomi Inoue Source Type: research
Delays in Presentation Time Under the COVID-19 Epidemic in Patients With Transient Ischemic Attack and Mild Stroke: A Retrospective Study of Three Hospitals in a Japanese Prefecture
Conclusions: The COVID-19 epidemic might increase the ODT of patients with TIA/mild stroke.
Source: Frontiers in Neurology - October 27, 2021 Category: Neurology Source Type: research
New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
DNA methylation level of the gene encoding thioredoxin-interacting protein in peripheral blood cells is associated with metabolic syndrome in the Japanese general population
Endocr J. 2021 Oct 14. doi: 10.1507/endocrj.EJ21-0339. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is cluster of metabolic diseases, including abdominal obesity, hyperglycemia, high blood pressure, and dyslipidemia, that directly escalate the risk of type 2 diabetes, heart disease, and stroke. Thioredoxin-interacting protein (TXNIP) is a binding protein for thioredoxin, a molecule that is a key inhibitor of cellular oxidation, and thus regulates the cellular redox state. Epigenetic alteration of the TXNIP-encoding locus has been associated with components of MetS. In the present study, we sought to determine wh...
Source: Endocrine Journal - October 14, 2021 Category: Endocrinology Authors: Mirai Yamazaki Hiroya Yamada Eiji Munetsuna Keisuke Maeda Yoshitaka Ando Genki Mizuno Ryosuke Fujii Yoshiki Tsuboi Koji Ohashi Hiroaki Ishikawa Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki Source Type: research
