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Condition: Depression
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Total 92 results found since Jan 2013.
Consensus statement for the management of incidentally found brain white matter hyperintensities in general medical practice
Med J Aust. 2023 Aug 21. doi: 10.5694/mja2.52079. Online ahead of print.ABSTRACTINTRODUCTION: There is a paradigm shift in our understanding of white matter hyperintensities (WMH) found on brain imaging. They were once thought to be a normal phenomenon of ageing and, therefore, warranted no further investigation. However, evidence now suggests these lesions are markers of poor brain and cardiovascular health, portending an increased risk of stroke, cognitive decline, depression and death. Nevertheless, no specific guidelines exist for the management of incidentally found WMH for general medical practitioners and other clin...
Source: Med J Aust - August 21, 2023 Category: General Medicine Authors: Thomas P Ottavi Elizabeth Pepper Grant Bateman Mark Fiorentino Amy Brodtmann Source Type: research
EXERTION: a pilot trial on the effect of aerobic, smartwatch-controlled exercise on stroke recovery: effects on motor function, structural repair, cognition, mental well-being, and the immune system
This study investigates the effect of smartwatch-controlled aerobic exercise on functional recovery, cognition, emotional well-being, the immune system, and neuronal network reorganization in stroke patients. Trial registration ClinicalTrials.gov NCT Number: NCT05690165. First posted19 January 2023. Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05690165.PMID:37170385 | DOI:10.1186/s42466-023-00244-w
Source: Cell Research - May 11, 2023 Category: Cytology Authors: Frederike A Straeten Stephanie van Zyl Bastian Maus Jochen Bauer Heiner Raum Catharina C Gross Sabine Bruchmann Nils C Landmeyer Cornelius Faber Jens Minnerup Antje Schmidt-Pogoda Source Type: research
Associations of carotid artery flow parameters with MRI markers of cerebral small vessel disease and patterns of brain atrophy
Cerebral small vessel disease (CSVD) affects small arteries, arterioles, veins and capillaries of the brain. Although a common and often silent condition occurring among healthy elderly people, it is associated with stroke, dementia, gait disturbances, cognitive decline and depression.1 –4 Magnetic resonance imaging (MRI) markers of CSVD include: white matter changes (WMC), microbleeds (MB) and lacunar infarctions (LAC).5 They can be investigated either individually or be viewed as a dynamic whole-brain disease.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2023 Category: Neurology Authors: Katarina Ellstr öm, Kasim Abul-Kasim, Arkadiusz Siennicki-Lantz, Sölve Elmståhl Source Type: research
Altered effective connectivity in the emotional network induced by immersive virtual reality rehabilitation for post-stroke depression
Post-stroke depression (PSD) is a serious complication of stroke that significantly restricts rehabilitation. The use of immersive virtual reality for stroke survivors is promising. Herein, we investigated the effects of a novel immersive virtual reality training system on PSD and explored induced effective connectivity alterations in emotional networks using multivariate Granger causality analysis (GCA). Forty-four patients with PSD were equally allocated into an immersive-virtual reality group and a control group. In addition to their usual rehabilitation treatments, the participants in the immersive-virtual reality grou...
Source: Frontiers in Human Neuroscience - August 2, 2022 Category: Neuroscience Source Type: research
Effectiveness and functional magnetic resonance imaging outcomes of Tuina therapy in patients with post-stroke depression: A randomized controlled trial
ConclusionTuina therapy administered 10 times within 2 weeks is safe and can effectively relieve depression and improve cognitive function in patients with PSD. This finding may be closely related to the effect of Tuina therapy on the activation and functional connectivity of the hippocampus.Clinical Trial Registrationhttp://www.chictr.org.cn/showproj.aspx?proj=55151, identifier ChiCTR200003388.
Source: Frontiers in Psychiatry - June 30, 2022 Category: Psychiatry Source Type: research
Concurrent TMS-fMRI: Technical Challenges, Developments, and Overview of Previous Studies
Transcranial magnetic stimulation (TMS) is a promising treatment modality for psychiatric and neurological disorders. Repetitive TMS (rTMS) is widely used for the treatment of psychiatric and neurological diseases, such as depression, motor stroke, and neuropathic pain. However, the underlying mechanisms of rTMS-mediated neuronal modulation are not fully understood. In this respect, concurrent or simultaneous TMS-fMRI, in which TMS is applied during functional magnetic resonance imaging (fMRI), is a viable tool to gain insights, as it enables an investigation of the immediate effects of TMS. Concurrent application of TMS d...
Source: Frontiers in Psychiatry - April 21, 2022 Category: Psychiatry Source Type: research
Improving Depressive Symptoms of Post-stroke Depression Using the Shugan Jieyu Capsule: A Resting-State Functional Magnetic Resonance Imaging Study
Regional homogeneity (ReHo) and fractional amplitude of low-frequency fluctuation (fALFF) were used to detect the neuroimaging mechanism of Shugan Jieyu Capsule (SG) in ameliorating depression of post-stroke depression (PSD) patients. Fifteen PSD patients took SG for 8 weeks, completed the 24-item Hamilton Depression Scale (HAMD) assessment at the baseline and 8 weeks later, and underwent functional magnetic resonance imaging (fMRI) scanning. Twenty-one healthy controls (HCs) underwent these assessments at the baseline. We found that SG improved depression of PSD patients, in which ReHo values decreased in the left calcari...
Source: Frontiers in Neurology - April 14, 2022 Category: Neurology Source Type: research
Symptomatic plaque enhancement is associated with early-onset post-stroke depression
CONCLUSIONS: The degree of symptomatic plaque enhancement is an independent predictive imaging marker of early-onset PSD and can be used the early diagnosis of early-onset PSD.PMID:35337924 | DOI:10.1016/j.jad.2022.03.026
Source: Atherosclerosis - March 26, 2022 Category: Cardiology Authors: Fan Liu Mingyu Song Xia Huang Hanxi Yi Hengshu Chen Fafa Tian Source Type: research
Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation for Post-stroke Vascular Cognitive Impairment: A Prospective Pilot Study
ConclusionsHigh-frequency rTMS on the ipsilesional DLPFC may exert immediate efficacy on cognition with the anti-inflammatory response and changes in brain network in PSCI, lasting at least 3 months.
Source: Frontiers in Neurology - March 22, 2022 Category: Neurology Source Type: research
Mechanisms of Repetitive Transcranial Magnetic Stimulation on Post-stroke Depression: A Resting-State Functional Magnetic Resonance Imaging Study
Brain Topogr. 2022 Mar 14. doi: 10.1007/s10548-022-00894-0. Online ahead of print.ABSTRACTWe aimed to identify neural mechanisms underlying clinical response to repetitive transcranial magnetic stimulation (rTMS) in post-stroke depression (PSD) by the Resting-state functional magnetic resonance imaging (rs-fMRI). Thirty-two depressed patients after ischemic stroke were randomized in a 1:1 ratio to receive 20 min of 5 Hz rTMS or sham over left dorsolateral prefrontal cortex (DLPFC) in addition to routine supportive treatments. The clinical outcome was measured by the 17-item Hamilton Depression Rating Scale (HDRS-17), while...
Source: Brain Topography - March 14, 2022 Category: Neuroscience Authors: Yamei Li Kuide Li Rongjian Feng Yi Li Yufeng Li Hong Luo Qian Yu Source Type: research
