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Total 97 results found since Jan 2013.

Ethnic Differences in Prevalence of Post-stroke Depression Original Articles
Conclusions: MAs had a higher prevalence of PSD at 90 days than NHWs. The ethnic difference was explained by sociodemographic and health factors, especially low educational attainment.
Source: Circulation: Cardiovascular Quality and Outcomes - January 25, 2018 Category: Cardiology Authors: Dong, L., Sanchez, B. N., Skolarus, L. E., Morgenstern, L. B., Lisabeth, L. D. Tags: Epidemiology, Mental Health, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

Inflammatory Signaling in Post-Stroke Fatigue and Depression
Background: In the United States, stroke continues to be the cause for long-term disability. Of the patients with a first stroke, up to 75% will experience post-stroke fatigue (PSF) in the first year following stroke. PSF is one of the most disabling symptoms in stroke survivors; it decreases quality of life, increases mortality, and is a barrier to stroke rehabilitation. Given the incidence of stroke and the prevalence and detrimental impact of PSF on quality of life, independent living, and overall survival, efficient management of PSF must be a priority in stroke rehabilitation. The cause of PSF remains unknown. The bur...
Source: European Neurology - November 16, 2018 Category: Neurology Source Type: research

Study protocol of a telephone problem-solving intervention for Spanish-speaking caregivers of veterans post-stroke: an 8-session investigator-blinded, two-arm parallel (intervention vs usual care), randomized clinical trial
This study tests the impact of a telephone and online problem-solving intervention for Spanish-speaking stroke caregivers on caregiver outcomes.METHODS: The design is a two-arm parallel randomized clinical trial with repeated measures. We will enroll 290 caregivers from 3 Veterans Affairs (VA) medical centers. Participants randomized into the intervention arm receive a problem-solving intervention that uses telephone and online education and care management tools on the previously developed and nationally available RESCUE en Español Caregiver website. In the usual care group, participants receive the information and/or su...
Source: Primary Care - March 18, 2023 Category: Primary Care Authors: I Magaly Freytes Magda K Schmitzberger Naiomi Rivera-Rivera Janet Lopez Keryl Motta-Valencia Samuel S Wu Tatiana Orozco Jennifer Hale-Gallardo Nathaniel Eliazar-Macke Jennifer H LeLaurin Constance R Uphold Source Type: research

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

The effects of racism and resilience on Black stroke- survivor quality of life: Study protocol and rationale for a mixed-methods approach
This study aims to examine the effects of experiences of racism and resilience on Black SS QoL during early stroke recovery. This article presents the study protocol.Methods and analysesThis will be a prospective observational mixed-methods study. Black community-dwelling adults who are within 4 weeks of a stroke will be eligible for inclusion. Baseline measures will include the exposure variables of experiences of racism and resilience. Covariates measured at baseline include sociodemographic variables (age, sex, marital status, education, income, health insurance, employment status, number of people in household, residen...
Source: Frontiers in Neurology - August 10, 2022 Category: Neurology Source Type: research

Exploring the bi-directional relationship and shared genes between depression and stroke via NHANES and bioinformatic analysis
Conclusion: We successfully identified the ten hub shared genes linking the IS and MDD and constructed the regulatory networks for them that could serve as novel targeted therapy for the comorbidities.
Source: Frontiers in Genetics - March 31, 2023 Category: Genetics & Stem Cells Source Type: research

Efficacy of repetitive transcranial magnetic stimulation for post-stroke depression: a systematic review and meta-analysis of randomized clinical trials.
In conclusion, from the current evidence in this study, rTMS could be an effective treatment for patients with PSD. Further clinical studies with larger sample sizes and clearer subgroup definitions are needed to confirm these outcomes. PMID: 33470386 [PubMed - in process]
Source: Brazilian Journal of Medical and Biological Research - January 21, 2021 Category: Research Tags: Braz J Med Biol Res Source Type: research

Suicide Following Stroke in the United States Veterans Health Administration Population
In the United States (US), suicide is a leading cause of death, and most of these suicides involve firearms, highlighting the importance of lethal means safety in suicide prevention.(1, 2) US Veterans experience a suicide rate 1.5 times higher than US civilian adults and are more likely to use firearms as the means of suicide.(3) Risk factors for suicide within this population include demographic factors such as sex, age, race, and level of education, as well as health factors such as smoking status, psychiatric conditions (e.g., posttraumatic stress disorder [PTSD], depression, bipolar and anxiety disorders, schizophrenia...
Source: Archives of Physical Medicine and Rehabilitation - March 31, 2021 Category: Rehabilitation Authors: Jordan M. Wyrwa, Tyler M. Shirel, Trisha A. Hostetter, Alexandra L. Schneider, Claire A. Hoffmire, Kelly A. Stearns-Yoder, Jeri E. Forster, Nathan E. Odom, Lisa A. Brenner Tags: Original Research Source Type: research

Association between hysterectomy status and stroke risk and cause-specific and all-cause mortality: evidence from the 2005 –2018 National Health and Nutrition Examination Survey
ConclusionOur study found a significant association between hysterectomy and stroke, even after adjusting for other factors that could impact risk, such as the American Heart Association (AHA)'s Life's Simple 7 cardiovascular health score and variables of age, ethnicity, marital status, income, education, and depression severity.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Efficacy of repetitive transcranial magnetic stimulation for post-stroke depression: a systematic review and meta-analysis of randomized clinical trials
In conclusion, from the current evidence in this study, rTMS could be an effective treatment for patients with PSD. Further clinical studies with larger sample sizes and clearer subgroup definitions are needed to confirm these outcomes.PMID:33470386 | PMC:PMC7812912 | DOI:10.1590/1414-431X202010010
Source: Braz J Med Biol Res - January 20, 2021 Category: Research Authors: D Shao Z N Zhao Y Q Zhang X Y Zhou L B Zhao M Dong F H Xu Y J Xiang H Y Luo Source Type: research

GETCare: Development of a Comprehensive Education and Training Program For Care-Partners Post-Stroke
Stroke is the leading cause of long-term disability in the United States, with spousal partners often filling a significant role as caregivers after loved ones return home. Without adequate resources, this new role can lead to increased burden and depression for care-partners, and decreased rehabilitation effectiveness for stroke survivors. Research suggests the quality and amount of education provided to care-partners is severely lacking and there is need for improved services and resources. The purpose of this project was to conduct a needs assessment, create the GETCare program, and gather stakeholder feedback in prepar...
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Jackie Einerson, Alexandra Terrill Source Type: research

Prevalence, patterns and predictors of depression treatment among community-dwelling older adults with stroke in the United States: a cross sectional study
Depression is one of the most common psychiatric conditions among stroke survivors and is associated with several negative health outcomes. However, little is known about the depression treatment patterns amon...
Source: BMC Psychiatry - May 16, 2018 Category: Psychiatry Authors: Sandipan Bhattacharjee, Majed Al Yami, Sawsan Kurdi and David Rhys Axon Tags: Research article Source Type: research

Stroke Risk among Elderly Users of Haloperidol and Typical Antipsychotics vs. Atypical Antipsychotics: A Real-World Study from a US Health Insurance Claims Database
Antipsychotics are approved and prescribed to treat various conditions such as schizophrenia, mania, major depressive disorder, agitation, delusional disorder, psychosis, and Tourette's syndrome1. The haloperidol prescribing information2 in the United States (US) does not warn about the risk of stroke but has a black box warning for an increased risk of death among elderly patients with dementia-related psychosis treated with antipsychotic drugs. Nonetheless, antipsychotics are used for indications such as neuropsychiatric symptoms of dementia, in the presence or absence of psychosis; such use is not approved by the Food a...
Source: The American Journal of Geriatric Psychiatry - September 25, 2020 Category: Geriatrics Authors: Daniel Fife, Clair Blacketer, R. Karl Knight, James Weaver Source Type: research