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Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Neurologic Complications After Pediatric Heart Transplant: A Single-Center Experience
CONCLUSIONS: Neurologic complications may lead to serious mortality and morbidity in pediatric heart transplant patients. Seizures, posterior reversible encephalopathy syndrome, stroke, peripheral neuropathy, transient ischemic attack, and cerebral infections are the most common neurologic complications, which are seen in the perioperative period in particular. Careful follow-up of pediatric heart transplant patients, with detection and early treatment of neurologic findings, will contribute to lower rates of sequelae. To our knowledge, this is the largest study to show a detailed experience of neurologic complications in ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 2, 2021 Category: Transplant Surgery Authors: Ali Orgun Ilkay Erdogan Birg ül Varan Taner Sezer N K ürsad Tokel Murat Özkan Atilla Sezgin Source Type: research

Inpatient Neurologic Consultation in Solid Organ Transplant Patients
Semin Neurol 2015; 35: 699-707DOI: 10.1055/s-0035-1564683A third of solid organ transplant recipients experience neurologic complications after transplantation. In this article the author reviews common and uncommon complications of the perioperative period including stroke and peripheral neuropathy, neurotoxicity associated with immunosuppressant medications such as calcineurin inhibitors, and opportunistic infections that target the nervous system. A careful clinical history, neurologic examination, and medication review are vital in generating a differential diagnosis that will guide diagnostic testing and decisions reg...
Source: Seminars in Neurology - November 23, 2015 Category: Neurology Authors: Shah, Maulik Source Type: research

Mortality of diabetic on chronic dialysis in Tunisia.
This study aims to specify the epidemio-logical, clinical, and biological characteristics of diabetic disease, chronic kidney disease (CKD), and comorbidities at the initiation of HD and investigate factors associated with mortality during the dialysis period. We retrospectively analyzed the outcome of diabetic patients who were initiated on HD from 2007 to 2012 at the Rabta Hospital of Tunis. During the follow-up period, all morbid events and deaths were recorded. Univariate analysis and multivariate analysis were performed to identify risk factors associated with mortality in our population. The study population included...
Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2018 Category: Urology & Nephrology Authors: Jebali H, Laifi M, Mami I, Khadhar M, Chirmiti M, Beji S, Rheder R, Smaoui W, Krid M, Hmida FB, Rais L, Fatma LB, Zouaghi MK Tags: Saudi J Kidney Dis Transpl Source Type: research

Transthyretin cardiac amyloidosis.
Authors: Eicher JC, Audia S, Damy T Abstract Transthyretin (TTR) cardiac amyloidosis results from the dissociation of the tetrameric, liver-synthetized transport protein, either because of a mutation (hereditary CA), or spontaneously due to ageing (wild type CA). Monomers self-associate into amyloid fibrils within the myocardium, causing heart failure, arrhythmias and conduction defects. This overlooked disease must be recognized in case of unexplained increased thickness of the myocardium, particularly in subjects of African descent, in patients with heart failure and preserved ejection fraction, and in those with...
Source: Revue de Medecine Interne - August 23, 2020 Category: Internal Medicine Tags: Rev Med Interne Source Type: research

Neuropathy and Muscle Cramps in Autologous and Allogeneic Hematopoietic Cell Transplantation Survivors
Hematopoietic cell transplantation (HCT) is a critical part of the armamentarium in the treatment of many hematologic malignancies. However, both allogeneic and autologous HCT may be associated with high morbidity in survivors. Neurological complications of HCT that may have long-term impact on quality of life (QOL) are often overlooked.1 Both the central nervous system (CNS) and peripheral nervous system (PNS) can be involved with CNS complications including infections, posterior reversible encephalopathy syndrome (PRES), seizures, and stroke being more prominent in the acute post-HCT period,2 and PNS complications such a...
Source: Biology of Blood and Marrow Transplantation - June 15, 2022 Category: Hematology Authors: Tanya Lehky, Iago Pinal Fernandez, Elizabeth F. Krakow, Laura Connelly-Smith, Rachel B. Salit, Phuong Vo, Masumi Ueda Oshima, Lynn Onstad, Paul A. Carpenter, Mary E. Flowers, Stephanie J Lee Source Type: research