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Condition: Obesity
Infectious Disease: Pandemics
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Total 2193 results found since Jan 2013.
"The obesity pandemic" in the COVID-19 pandemic - new treatment for an old problem
This article provides a review of the literature on the recent worsening of obesity in the paediatric population, with particular emphasis on the importance of the COVID-19 pandemic. New methods of fighting obesity with the use of telemedicine and current methods of pharmacotherapy, including new drugs, are presented.PMID:37728462 | PMC:PMC10411083 | DOI:10.5114/pedm.2023.129342
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kalina Fabin-Czepiel Karolina Pieczy ńska-Chapuła Gra żyna Deja Source Type: research
Temporal Changes in Energy-Balance Behaviors and Home Factors in Adolescents with Normal Weight and Those with Overweight or Obesity
This study aimed to examine the temporal changes in energy-balance behaviors and home factors in adolescents with normal weight and those with overweight or obesity (OWOB). Adolescents or parent proxies completed survey assessments two to four years before (T0; n=82), ≤ six months before (T1; n=68), and ≤ three months after the COVID-19 pandemic outbreak (T2; n=82), to capture energy-balance behaviors (i.e., physical activity [PA], screen time, sleep) and home factors (i.e., food environment, food worry, parent support for PA). At T0 and T1 (before pandemic), participants visited our laboratory for anthropometric measu...
Source: Health Physics - September 7, 2023 Category: Physics Authors: Senlin Chen Chelsea L Kracht Robbie A Beyl Amanda E Staiano Source Type: research
Association between Heavy Metals, Metalloids and Metabolic Syndrome: New Insights and Approaches
Toxics. 2023 Aug 3;11(8):670. doi: 10.3390/toxics11080670.ABSTRACTMetabolic syndrome (MetS) is an important public health issue that affects millions of people around the world and is growing to pandemic-like proportions. This syndrome is defined by the World Health Organization (WHO) as a pathologic condition characterized by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. Moreover, the etiology of MetS is multifactorial, involving many environmental factors, including toxicant exposures. Several studies have associated MetS with heavy metals exposure, which is the focus of this review. Environmen...
Source: Atherosclerosis - August 25, 2023 Category: Cardiology Authors: Airton C Martins Beatriz Ferrer Alexey A Tinkov Samuel Caito Romina Deza-Ponzio Anatoly V Skalny Aaron B Bowman Michael Aschner Source Type: research
Bariatric surgery alters mitochondrial function in gut mucosa
CONCLUSION: Ileal interposition decreases mitochondrial volume in the proximal intestinal mucosa of mice. This change in concentration with preserved respiration suggests a global mucosal response to segment specific nutrition signals in the distal bowel. Future studies are required to understand the causes underlying these mitochondrial changes.PMID:37620650 | DOI:10.1007/s00464-023-10351-z
Source: Cancer Control - August 24, 2023 Category: Cancer & Oncology Authors: Robert C Ross Elizabeth C Heintz Elizabeth R M Zunica R Leigh Townsend Amanda E Spence Philip R Schauer John P Kirwan Christopher L Axelrod Vance L Albaugh Source Type: research
Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism
In this study, we employed scaffold hopping and simplification strategies to design and synthesize two new series derivatives by modifying the D ring. Extensive discussions have been conducted regarding the structure-activity relationship between lipid-lowering activity and the new compounds. These discussions have resulted in the discovery of 2-pyrimidinylindole derivatives as a promising scaffold for anti-obesity treatment. The new 2-pyrimidinylindole derivatives exhibited comparable lipid-lowering activity to the previously reported indolylquinazoline derivatives, including SYSU-3d and R17, with reduced toxicity. The mo...
Source: European Journal of Medicinal Chemistry - August 22, 2023 Category: Chemistry Authors: Shi-Yao Guo Li-Yuan Wei Bing-Bing Song Yu-Tao Hu Zhi Jiang Dan-Dan Zhao Yao-Hao Xu Yu-Wei Lin Shu-Min Xu Shuo-Bin Chen Zhi-Shu Huang Source Type: research
Downregulated adipose tissue expression of browning genes with increased environmental temperatures
CONCLUSIONS: Decreased adipose tissue expression of genes involved in browning and adiponectin with increased environmental temperatures were observed. Given the North-South gradient of obesity prevalence in these same regions, current observations could have implications for the relationship of the obesity pandemic with global warming.PMID:37560997 | DOI:10.1210/clinem/dgad469
Source: The Journal of Clinical Endocrinology and Metabolism - August 10, 2023 Category: Endocrinology Authors: N úria Oliveras-Cañellas Jos é María Moreno-Navarrete Paula M Lorenzo Lourdes Garrido-S ánchez Sara Becerril Oriol Rangel J èssica Latorre Elena de la Calle Vargas Maria Pardo Victor Valent í Juan L Romero-Cabrera Wilfredo Oliva-Olivera Camilo Silv Source Type: research
Elucidating the primary mechanisms of high-intensity interval training for improved cardiac fitness in obesity
In conclusion, HIIT has been shown to reduce obesity-induced risks of cardiac remodeling, but the long-term effects of HIIT on obesity-induced cardiac injury and disease are presently unknown. Collective understanding highlights numerous specific research that are needed before the safety and effectiveness of HIIT can be confirmed and widely adopted in patient with obesity.
Source: Frontiers in Physiology - August 7, 2023 Category: Physiology Source Type: research
The Molecular and Genetic Interactions between Obesity and Breast Cancer Risk
Medicina (Kaunas). 2023 Jul 21;59(7):1338. doi: 10.3390/medicina59071338.ABSTRACTBreast cancer (BC) is considered the leading cause of death among females worldwide. Various risk factors contribute to BC development, such as age, genetics, reproductive factors, obesity, alcohol intake, and lifestyle. Obesity is considered to be a pandemic health problem globally, affecting millions of people worldwide. Obesity has been associated with a high risk of BC development. Determining the impact of obesity on BC development risk in women by demonstrating the molecular and genetic association in pre- and post-menopause females and ...
Source: Medicina (Kaunas) - July 29, 2023 Category: Universities & Medical Training Authors: Ghada M A Ajabnoor Source Type: research
