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Condition: Metabolic Syndrome
Nutrition: Diets
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Total 2122 results found since Jan 2013.
Effects of epicatechin on cardiovascular function in middle-aged diet-induced obese rat models of metabolic syndrome
This study aimed to investigate the cardiovascular effects of epicatechin, a flavonoid found in green tea and cocoa, in attenuating complications associated with metabolic syndrome in diet-induced obese rats.Male Wistar-Kyoto (WKY) rats aged 16 weeks were fed either standard rat chow (SC) or given a high-fat-high-carbohydrate (HFHC) diet for 20 weeks. Epicatechin treatment (5mg/kg/day) was administered to a subset of WKY rats commencing at week 8 of the 20 week HFHC feeding period. Body weights, food, water and energy intakes, blood pressure, heart rate and glucose tolerance were measured throughout the treatment period. O...
Source: The British Journal of Nutrition - September 21, 2023 Category: Nutrition Authors: Kylie Connolly Romeo Batacan Douglas Jackson Andrew Fenning Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice
CONCLUSIONS: Our study demonstrated that IX prevents obesity and enhances glucose metabolism by inhibiting dietary fat absorption. This mechanism is linked to suppressing pancreatic lipase activity and shifts in microbial composition, notably an increase in A. muciniphila. These highlight new treatment strategies for preventing metabolic syndrome by boosting the gut microbiota with food components.PMID:37709134 | DOI:10.1016/j.molmet.2023.101797
Source: Molecular Medicine - September 14, 2023 Category: Molecular Biology Authors: Yoshiyuki Watanabe Shiho Fujisaka Yoshitomo Morinaga Shiro Watanabe Allah Nawaz Hideki Hatta Tomonobu Kado Ayumi Nishimura Muhammad Bilal Muhammad Rahil Aslam Keiko Honda Yoshimi Nakagawa Samir Softic Kenichi Hirabayashi Takashi Nakagawa Yoshinori Nagai K Source Type: research
High Maternal Adiposity During Pregnancy Programs an Imbalance in the Lipidome and Predisposes to Diet-induced Hepatosteatosis in the Offspring
CONCLUSION: High maternal adiposity during pregnancy programs a susceptibility to diet-induced hepatosteatosis.PMID:37706282 | DOI:10.1042/BSR20231060
Source: Bioscience Reports - September 14, 2023 Category: Biomedical Science Authors: Taylor B Scheidl Jessica L Wager Larissa G Baker Amy L Brightwell Katrina M Melan Sebastian Larion Ousseynou Sarr T R Regnault Stefan J Urbanski Jennifer Thompson Source Type: research
HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity
CONCLUSION: Therefore, HDAC3 inhibition can represent a promising pharmacological target for the treatment of obesity.PMID:37698830 | DOI:10.1007/s43440-023-00528-7
Source: Pharmacological Reports - September 12, 2023 Category: Drugs & Pharmacology Authors: Franci éle Romero Machado Silvana Peterini Boeira Vandreza Cardoso Bortolotto St ífani Machado Araujo M árcia Rósula Poetini Cristini Escobar Viana Marina Prigol Leandro Cattelan Souza Marcelo Gomes de Gomes Source Type: research
Normolipidic diet containing deep-fried saturated and unsaturated fatty acids rich edible oils promotes metabolic dysregulation and inflammatory microenvironment in Wistar rats
This study investigated the influence of prolonged consumption of thermally oxidised long-chain saturated and unsaturated edible oils on metabolic dysregulation and inflammation. The thermally oxidised oils used in the study possess higher p-anisidine values and free fatty acid contents compared to unoxidised oils. Fourier transform infrared spectroscopy and fatty acid methyl ester analysis confirmed the presence of free fatty acids, hydroperoxides, and aldehydes, formed during thermal oxidation. The study analysed the effects of dietary intake of 5% sunflower oil, palm oil, and their thermally-oxidised forms in male Wista...
Source: Food and Chemical Toxicology - September 8, 2023 Category: Food Science Authors: Sruthi Panniyan Kandiyil Soorya Parathodi Illam Achuthan C Raghavamenon Source Type: research
Educational inequalities in metabolic syndrome prevalence, timing, and duration amongst adults over the life course: a microsimulation analysis based on the lifelines cohort study
CONCLUSIONS: Interventions targeting the modifiable factors included in this study, especially smoking, could help reduce the estimated educational inequalities in MetS over the life course.PMID:37667275 | DOI:10.1186/s12966-023-01495-1
Source: Health Physics - September 4, 2023 Category: Physics Authors: Liza A Hoveling Alexander Lepe Michael Boissonneault Joop A A de Beer Nynke Smidt Marlou L A de Kroon Aart C Liefbroer Source Type: research
Linking serum vitamin D levels with gut microbiota after 1-year lifestyle intervention with Mediterranean diet in patients with obesity and metabolic syndrome: a nested cross-sectional and prospective study
Gut Microbes. 2023 Dec;15(2):2249150. doi: 10.1080/19490976.2023.2249150.ABSTRACTVitamin D, microbiota, and the Mediterranean diet (MedDiet) have been the focus of recent research due to their potential role in maintaining overall health. We hypothesize that MedDiet may alter the gut microbiota profile through changes in vitamin D levels. We aimed to investigate changes in gut microbiota and serum vitamin D levels after a MedDiet within a lifestyle intervention. The study included 91 patients with obesity and metabolic syndrome, who were categorized based on their serum vitamin D levels as having either optimal or low 25-h...
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Hatim Boughanem Patricia Ruiz-Lim ón Jes ús Pilo Jos é Manuel Lisbona-Montañez Francisco J Tinahones Isabel Moreno Indias Manuel Mac ías-González Source Type: research
High-fat diet during pregnancy promotes fetal skeletal muscle fatty acid oxidation and insulin resistance in an ovine model
We examined the effects of a high-fat diet (HFD) during pregnancy on fetal skeletal muscle metabolism and metabolic risk parameters using an ovine model. White-faced ewes were fed standardized diet containing 5% fat w/w (CON), or the same diet supplemented with 6% rumen-protected fats (11% total fat w/w; HFD) beginning two weeks before mating until mid-gestation (GD75). Maternal HFD increased maternal weight gain, fetal body weight, and low-density lipoprotein levels in the uterine and umbilical circulation, but had no significant effects on circulating glucose, triglycerides or placental fatty acid transporters. Fatty aci...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - August 29, 2023 Category: Physiology Authors: Asma K Omar Lance C Li Puma Luke A Whitcomb Briana D Risk Aria C Witt Jason E Bruemmer Quinton A Winger Gerrit J Bouma Adam J Chicco Source Type: research
