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Total 616 results found since Jan 2013.
Effects of epicatechin on cardiovascular function in middle-aged diet-induced obese rat models of metabolic syndrome
This study aimed to investigate the cardiovascular effects of epicatechin, a flavonoid found in green tea and cocoa, in attenuating complications associated with metabolic syndrome in diet-induced obese rats.Male Wistar-Kyoto (WKY) rats aged 16 weeks were fed either standard rat chow (SC) or given a high-fat-high-carbohydrate (HFHC) diet for 20 weeks. Epicatechin treatment (5mg/kg/day) was administered to a subset of WKY rats commencing at week 8 of the 20 week HFHC feeding period. Body weights, food, water and energy intakes, blood pressure, heart rate and glucose tolerance were measured throughout the treatment period. O...
Source: The British Journal of Nutrition - September 21, 2023 Category: Nutrition Authors: Kylie Connolly Romeo Batacan Douglas Jackson Andrew Fenning Source Type: research
Are menstrual disorders in adolescent girls related to metabolic disorders?
CONCLUSIONS: Adolescent girls with menstrual disorders are insulin resistant, regardless of PCOS diagnosis. The severity of menstrual disorders may be related to the incidence of lipid disorders in adolescent girls.PMID:37728458 | PMC:PMC10411084 | DOI:10.5114/pedm.2023.125364
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: El żbieta Foryś Adrianna Baran Aleksandra Dziurdzia Ewelina Jarosz-W ójcik Pawe ł Matusik Aneta Gawlik Ryszard Tomaszewski Agnieszka Zachurzok Source Type: research
Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Insulin Resistance and Hypertension: Mechanisms Involved and Modifying Factors for Effective Glucose Control
Biomedicines. 2023 Aug 15;11(8):2271. doi: 10.3390/biomedicines11082271.ABSTRACTFactors such as aging, an unhealthy lifestyle with decreased physical activity, snacking, a standard Western diet, and smoking contribute to raising blood pressure to a dangerous level, increasing the risk of coronary artery disease and heart failure. Atherosclerosis, or aging of the blood vessels, is a physiological process that has accelerated in the last decades by the overconsumption of carbohydrates as the primary sources of caloric intake, resulting in increased triglycerides and VLDL-cholesterol and insulin spikes. Classically, medicatio...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Hussein F Sakr Srinivasa Rao Sirasanagandla Srijit Das Abdulhadi I Bima Ayman Z Elsamanoudy Source Type: research
Almonds vs. carbohydrate snacks in an energy-restricted diet: Weight and cardiometabolic outcomes from a randomized trial
CONCLUSIONS: An energy-restricted AED resulted in weight loss and weight loss maintenance comparable to an energy-restricted NFD, and both diets supported cardiometabolic health. The AED resulted in greater improvements in some lipoprotein subfractions, which may enhance reductions in cardiovascular risk.PMID:37621033 | DOI:10.1002/oby.23860
Source: Obesity - August 25, 2023 Category: Eating Disorders & Weight Management Authors: Sharayah Carter Alison M Hill Lauren C Mead Hoi Y Wong Catherine Yandell Jonathan D Buckley Sze-Yen Tan Geraint B Rogers Francois Fraysse Alison M Coates Source Type: research
Acute statin withdrawal does not interfere with the improvements of a session of exercise in postprandial metabolism
CONCLUSIONS: In dyslipidemic individuals, statins reduce blood triglyceride concentrations after a meal, but without limiting fat oxidation. Statins do not interfere with the exercise lowering of postprandial insulin that likely promotes fat oxidation. Lastly statins do not restrict the rates of plasma incorporation or oxidation of the ingested glucose.CLINICALTRIALS.GOV IDENTIFIER: NCT04477590.PMID:37565392 | DOI:10.1210/clinem/dgad477
Source: The Journal of Clinical Endocrinology and Metabolism - August 11, 2023 Category: Endocrinology Authors: Laura Alvarez-Jimenez Felix Morales-Palomo Alfonso Moreno-Caba ñas Juan F Ortega Diego Mora-Gonzalez Ricardo Mora-Rodriguez Source Type: research
High-Throughput Sequencing Technology Assisted Investigation of the Correlation between Intestinal Flora, Serum Biochemistry, Blood Lipids, and Tumour Markers in Patients with Gastric Cancer and Healthy Plateau Residents
Conclusion There were significant differences in total protein, globulin, total cholesterol, high density lipoprotein, low-density lipoprotein, alpha-fetoprotein and carbohydrate antigen CA72-4 in patients with gastric cancer in the plateau area compared with the healthy group, and the different clinical variables were correlated with intestinal flora at some phylum and genus levels.PMID:37559540 | DOI:10.2174/1386207326666230808110029
Source: Combinatorial Chemistry and High Throughput Screening - August 10, 2023 Category: Chemistry Authors: Linghong Zhu Bo Wang Linxun Liu Pei Han Li Ji Zilong Zhang Jingni Zhang Source Type: research
