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Condition: Cholesterol

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Total 66 results found since Jan 2013.

Persistent User Bias in Case-Crossover Studies in Pharmacoepidemiology
In this study, our aim was to assess the occurrence of this bias and to evaluate whether it is remedied by including a control group (the case-time-control design). Using Danish data resources from 1995–2012, we conducted case-crossover and case-time-control analyses for 3 medications (statins, insulin, and thyroxine) in relation to 3 outcomes (retinal detachment, wrist fracture, and ischemic stroke), all with assumed null associations. Controls were matched on age, sex, and index date, and exposure over the preceding 12 months was ascertained. For retinal detachment, the case-crossover odds ratio was 1.60 (95% confi...
Source: American Journal of Epidemiology - November 13, 2016 Category: Epidemiology Authors: Hallas, J., Pottegard, A., Wang, S., Schneeweiss, S., Gagne, J. J. Tags: RESEARCH-ARTICLE Source Type: research

Surveillance for Certain Health Behaviors and Conditions Among States and Selected Local Areas - Behavioral Risk Factor Surveillance System, United States, 2013 and 2014.
Abstract PROBLEM: Chronic diseases and conditions (e.g., heart diseases, stroke, arthritis, and diabetes) are the leading causes of morbidity and mortality in the United States. These conditions are costly to the U.S. economy, yet they are often preventable or controllable. Behavioral risk factors (e.g., excessive alcohol consumption, tobacco use, poor diet, frequent mental distress, and insufficient sleep) are linked to the leading causes of morbidity and mortality. Adopting positive health behaviors (e.g., staying physically active, quitting tobacco use, obtaining routine physical checkups, and checking blood pr...
Source: MMWR Surveill Summ - September 15, 2017 Category: Epidemiology Authors: Gamble S, Mawokomatanda T, Xu F, Chowdhury PP, Pierannunzi C, Flegel D, Garvin W, Town M Tags: MMWR Surveill Summ Source Type: research

Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach
AbstractChronological age alone is not a sufficient measure of the true physiological state of the body. The aims of the present study were to: (1) quantify biological age based on a physiological biomarker composite model; (2) and evaluate its association with death and age-related disease onset in the setting of an elderly population. Using structural equation modeling we computed biological age for 1699 individuals recruited from the first and second waves of the Rotterdam study. The algorithm included nine physiological parameters (c-reactive protein, creatinine, albumin, total cholesterol, cytomegalovirus optical dens...
Source: European Journal of Epidemiology - April 12, 2019 Category: Epidemiology Source Type: research

Grading of Japanese Diet Intakes by 24-Hour Urine Analysis of Taurine and Soy Isoflavones in Relation to Cardiovascular Risks
In conclusion, the higher the J score, which corresponds to Japanese dietary habits, the lower the BMI and cholesterol levels, as well as mortality rate from coronary heart disease, but the higher the average life expectancy among the Japanese. However, these higher J scorings were associated with high-salt intake and high Na/K ratios; therefore, they contributed to high blood pressure and high mortality rate caused by stroke in Japan. These results indicate that low-salt intake should be recommended to the Japanese who are consuming seafood and soy regularly in order to maintain lower blood pressure and to extend healthy ...
Source: Adv Data - July 26, 2022 Category: Epidemiology Authors: Mari Mori Miki Sagara Hideki Mori Yukio Yamori Source Type: research

Prevalence of the metabolic syndrome in the old institutionalized people in Zagreb, Croatia.
Abstract Metabolic syndrome (MeS) is defined by a cluster of abnormalities comprising obesity, hypertension, carbohydrate intolerance and dyslipidemia. MeS increases the risk of developing various diseases, including coronary heart disease, stroke, peripheral angiopathy and type 2 diabetes. In our study, the subjects were 561 persons, residents of 11 homes for the elderly in Zagreb, Croatia. There were 160 men (28.5%) and 401 women (71.5%), aged from 56 to 96 years (the average being 79 years). Physical examination was conducted, which included blood pressure measurement, and body height and weight. Blood samples ...
Source: Collegium Antropologicum - March 1, 2013 Category: Epidemiology Authors: Nevajda B, Havelka-Mestrović A, Bilić M, Nevajda AP, Romić D, Vuletić V, Cukljek S, Sicaja M, Bocina Z Tags: Coll Antropol Source Type: research

CDC National Health Report: Leading Causes of Morbidity and Mortality and Associated Behavioral Risk and Protective Factors-United States, 2005-2013.
This report reviews population health in the United States and provides an assessment of recent progress in meeting high-priority health objectives. The health status indicators described in this report were selected because of their direct relation to the leading causes of death and other substantial sources of morbidity and mortality and should be the focus of prevention efforts. REPORTING PERIOD COVERED: Data are reported starting in 2005 (or the earliest available year since 2005) through the current data year. Because data sources and specific indicators vary regarding when data are available, the most recent yea...
Source: MMWR Surveill Summ - October 31, 2014 Category: Epidemiology Authors: Johnson NB, Hayes LD, Brown K, Hoo EC, Ethier KA Tags: MMWR Surveill Summ Source Type: research

Multiple biomarker models for improved risk estimation of specific cardiovascular diseases related to metabolic syndrome: a cross-sectional study
Conclusion: The reduced joint association modeling results suggest that unique combinations of biomarkers with their related measure of association can be used to produce more accurate cumulative risk estimates for each CVD. Additionally, our results indicate that the use of multiple biomarkers in a single multivariate model may provide increased accuracy of individual biomarker association estimates by controlling for statistical artifacts and spurious relationships due to co-biomarker confounding.
Source: Population Health Metrics - March 14, 2015 Category: Epidemiology Authors: Evan CoffmanJennifer Richmond-Bryant Source Type: research

A pooled analysis of the association of isolated low levels of high-density lipoprotein cholesterol with cardiovascular mortality in Japan
In conclusion, isolated low HDL-C levels are not associated with increased risk of CHD in Japan. CHD risk may, therefore, be more strongly affected by serum total cholesterol levels in this population.
Source: European Journal of Epidemiology - October 4, 2016 Category: Epidemiology Source Type: research

Risk prediction models for mortality in patients with cardiovascular disease: The BioBank Japan project.
CONCLUSIONS: We developed and validated risk prediction models of all-cause and cardiovascular death for patients with chronic ischemic CVD. These models would be useful for estimating the long-term risk of mortality in chronic phase CVD. PMID: 28142037 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - February 1, 2017 Category: Epidemiology Tags: J Epidemiol Source Type: research

Coffee intake, cardiovascular disease and all-cause mortality: observational and Mendelian randomization analyses in 95 000–223 000 individuals
Conclusions:</strong> Observationally, coffee intake was associated with U-shaped lower risk of cardiovascular disease and all-cause mortality; however, genetically caffeine intake was not associated with risk of cardiovascular disease or all-cause mortality.</span>
Source: International Journal of Epidemiology - December 29, 2016 Category: Epidemiology Source Type: research

Surveillance for Certain Health Behaviors and Conditions Among States and Selected Local Areas - Behavioral Risk Factor Surveillance System, United States, 2015.
This report presents results for all 50 states, the District of Columbia, the Commonwealth of Puerto Rico (Puerto Rico), and Guam and for 130 metropolitan and micropolitan statistical areas (MMSAs) (N = 441,456 respondents) for 2015. RESULTS: The age-adjusted prevalence estimates of health-risk behaviors, self-reported chronic health conditions, access to and use of health care, and use of preventive health services varied substantially by state, territory, and MMSA in 2015. Results are summarized for selected BRFSS measures. Each set of proportions refers to the median (range) of age-adjusted prevalence estimates for...
Source: MMWR Surveill Summ - June 29, 2018 Category: Epidemiology Authors: Pickens CM, Pierannunzi C, Garvin W, Town M Tags: MMWR Surveill Summ Source Type: research

Vascular Risk Factors and Findings on Brain MRI of Elderly Adult American Indians: The Strong Heart Study
Conclusions: This study found risk factors for cerebrovascular disease in American Indians similar to those seen in other populations and provides additional evidence for the important roles of hypertension and diabetes in promoting cerebral infarcts and brain atrophy, respectively.Neuroepidemiology 2019;52:173 –180
Source: Neuroepidemiology - January 27, 2019 Category: Epidemiology Source Type: research

Lifestyle Risk Factors and Findings on Brain Magnetic Resonance Imaging of Older Adult American Indians: The Strong Heart Study
Conclusions: This study found similar associations between smoking and vascular brain injury among American Indians, as seen in other populations. In particular, these findings support the role of smoking as a key correlate for cerebral atrophy.Neuroepidemiology
Source: Neuroepidemiology - June 4, 2019 Category: Epidemiology Source Type: research

Statin use and high-dose statin use after ischemic stroke in the UK: a retrospective cohort study
Source: Clinical Epidemiology - June 28, 2019 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Exploring the causal roles of circulating remnant lipid profile on cardiovascular and cerebrovascular diseases: Mendelian randomization study.
Conclusions The remnant lipids presented heterogeneity and two-sided effects for the risk of CHD and IS that may partially rely on the particle size. The findings suggested that the remnant lipids were required to be intervened according to specific components. This research confirms the importance of remnant lipids and provides causal evidence for potential targets for intervention. PMID: 33441507 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - January 16, 2021 Category: Epidemiology Tags: J Epidemiol Source Type: research