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Condition: Heart Disease
Procedure: Transplants

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Total 115 results found since Jan 2013.

Ten-point plan to tackle liver disease published
"Doctors call for tougher laws on alcohol abuse to tackle liver disease crisis," The Guardian reports. But this is just one of 10 recommendations for tackling the burden of liver disease published in a special report in The Lancet.The report paints a grim picture of an emerging crisis in liver disease in the UK, saying it is one of the few countries in Europe where liver disease and deaths have actually increased rapidly over the last 30 years. It concludes with 10 recommendations to tackle the burden of liver disease.The media has approached the recommendations from many different angles, with many sources only ...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Food/diet Lifestyle/exercise QA articles Source Type: news

Epigenetic regulation of smooth muscle cell plasticity
This article is part of a Special Issue entitled: Stress as a fundamental theme in cell plasticity.
Source: Biochimica et Biophysica Acta (BBA) Gene Regulatory Mechanisms - March 19, 2015 Category: Genetics & Stem Cells Source Type: research

“Framingham score, renal dysfunction and cardiovascular risk in liver transplant patients”
Conclusions: In our series, the FRS and eGFR at LT were able to predict the development of post‐LT CV events and poor outcome. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - March 30, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Articles Source Type: research

Framingham score, renal dysfunction, and cardiovascular risk in liver transplant patients
Cardiovascular (CV) events represent major impediments to the long‐term survival of liver transplantation (LT) patients. The aim of this study was to assess whether the Framingham risk score (FRS) at transplantation can predict the development of post‐LT cardiovascular events (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV risk factors, and CVEs occurring after LT (ischemic heart disease, stroke, heart failure, de novo arrhythmias, and peripheral arterial disease) were recorded. In total, 250 patients (69.6% men) with a median age of 56 years (range, 18‐68 years) were included...
Source: Liver Transplantation - May 26, 2015 Category: Transplant Surgery Authors: Tommaso Di Maira, Angel Rubin, Lorena Puchades, Victoria Aguilera, Carmen Vinaixa, Maria Garcia, Nicola De Maria, Erica Villa, Rafael Lopez‐Andujar, Fernando San Juan, Eva Montalva, Judith Perez, Martin Prieto, Marina Berenguer Tags: Original Article Source Type: research

Has Brazil found the way to better health care?
Under Brazil’s family health program, when a woman learns that she is pregnant, she contacts her local community health agent, who often is a neighbor. Typically, the agent visits her home to arrange an appointment with the neighborhood’s family health team, and the woman visits the health center for an assessment by a nurse assistant and a physician. During the pregnancy, if she misses a prenatal care appointment, the agent checks in on her at home and helps her reschedule her visit. Any prenatal medications she needs are provided free of charge. Brazil — home to the world’s fifth-largest population and seventh-l...
Source: UCLA Newsroom: Health Sciences - June 5, 2015 Category: Universities & Medical Training Source Type: news

Pre-existing diabetes and risks of morbidity and mortality after liver transplantation: A nationwide database study in an Asian population.
CONCLUSION: DM is associated with elevated risk of 90-day post-LTx. Moreover, DM patients with coexisting renal manifestations exhibited an increased postoperative risk of mortality after LTx. PMID: 26048000 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - June 2, 2015 Category: Internal Medicine Authors: Tsai MS, Wang YC, Wang HH, Lee PH, Jeng LB, Kao CH Tags: Eur J Intern Med Source Type: research

Disrupting Today's Healthcare System
This week in San Diego, Singularity University is holding its Exponential Medicine Conference, a look at how technologists are redesigning and rebuilding today's broken healthcare system. Healthcare today is reactive, retrospective, bureaucratic and expensive. It's sick care, not healthcare. This blog is about why the $3 trillion healthcare system is broken and how we are going to fix it. First, the Bad News: Doctors spend $210 billion per year on procedures that aren’t based on patient need, but fear of liability. Americans spend, on average, $8,915 per person on healthcare – more than any other count...
Source: Healthy Living - The Huffington Post - November 9, 2015 Category: Consumer Health News Source Type: news

Outcomes of ventricular assist device implantation in children and young adults: the Melbourne experience
ConclusionsChildren requiring pre‐transplant VAD support have a higher mortality and morbidity compared with young adults. Survival after heart transplantation those supported with VADs was similar to patients of similar age who did not require pre‐transplant support.
Source: ANZ Journal of Surgery - November 27, 2015 Category: Surgery Authors: William Y. Shi, Silvana F. Marasco, Pankaj Saxena, Yves d'Udekem, Matthew S. Yong, Sergei Mitnovetski, Christian P. Brizard, David C. McGiffin, Robert G. Weintraub, Igor E. Konstantinov Tags: Original Article Source Type: research

Intramyocardially transplanted neonatal cardiomyocytes show structural and electrophysiological maturation and integration and dose-dependently stabilize function of infarcted rat hearts.
Abstract Cardiac cell replacement therapy is a promising therapy to improve cardiac function in heart failure. Persistence, structural and functional maturation and integration of transplanted cardiomyocytes into recipient's hearts are crucial for a safe and efficient replacement of lost cells. We studied histology, electrophysiology and quantity of intramyocardially transplanted rat neonatal cardiomyocytes (NCM) and performed a detailed functional study with repeated invasive (pressure-volume-catheter) and non-invasive (echocardiography) analyses of infarcted female rat hearts including pharmacological stress bef...
Source: Cell Transplantation - August 16, 2016 Category: Cytology Authors: Maass M, Krausgrill B, Eschrig S, Kaluschke T, Urban K, Peinkofer G, Plenge TG, Oeckenpöhler S, Raths M, Ladage D, Halbach M, Hescheler J, Müller-Ehmsen J Tags: Cell Transplant Source Type: research

As Drug Deaths Soar, a Silver Lining for Transplant Patients
Drug users are the fastest-growing category of organ donor, and now rank fourth behind victims of stroke, blunt trauma and heart disease.
Source: NYT Health - October 6, 2016 Category: Consumer Health News Authors: KATHARINE Q. SEELYE Tags: Transplants Organ Donation Drug Abuse and Traffic Ethics and Official Misconduct Source Type: news

Outcomes in patients with diabetes 10 years after liver transplantation
ConclusionsIn our study, diabetes was associated with a higher risk of liver graft rejection and cardiovascular events. There was also a trend to higher mortality, although the effect was not statistically significant. These findings suggest that patients with diabetes require a more rigorous pretransplant evaluation and closer monitoring after transplantation, in order to try to reduce associated complications.
Source: Journal of Diabetes - December 31, 2016 Category: Endocrinology Authors: Agust ín Ramos‐prol, David Hervás‐marín, Alia GarcÍa‐castell, Juan Francisco Merino‐torres Tags: Original Article Source Type: research

Sickle Cell Disease with Cyanotic Congenital Heart Disease: Long-Term Outcomes in 5 Children.
Abstract Sickle cell disease is a risk factor for cerebrovascular accidents in the pediatric population. This risk is compounded by hypoxemia. Cyanotic congenital heart disease can expose patients to prolonged hypoxemia. To our knowledge, the long-term outcome of patients who have combined sickle cell and cyanotic congenital heart disease has not been reported. We retrospectively reviewed patient records at our institution and identified 5 patients (3 girls and 2 boys) who had both conditions. Their outcomes were uniformly poor: 4 died (age range, 12 mo-17 yr); 3 had documented cerebrovascular accidents; and 3 dev...
Source: Texas Heart Institute Journal - November 30, 2016 Category: Cardiology Authors: Iannucci GJ, Adisa OA, Oster ME, McConnell M, Mahle WT Tags: Tex Heart Inst J Source Type: research

Outcomes in patients with diabetes 10  years after liver transplantation
ConclusionsIn the present study diabetes was associated with a higher risk of liver graft rejection and cardiovascular events. There was also a trend for higher mortality, although the effect was not statistically significant. These findings suggest that patients with diabetes require a more rigorous pretransplant evaluation and closer monitoring after transplantation in order to try to reduce associated complications.
Source: Journal of Diabetes - February 27, 2017 Category: Endocrinology Authors: Agust ín Ramos‐Prol, David Hervás‐Marín, Alia García‐Castell, Juan F. Merino‐Torres Tags: Original Article Source Type: research

Thirty years of heart transplantation at the University Medical Centre Utrecht.
CONCLUSION: Over the past 30 years, patient and donor demographics and underlying diseases have shifted substantially. Furthermore, the increase in waiting time due to lack of available donor hearts has led to a rise in the use of LVADs as bridge to transplant. Importantly, an improvement in survival rates is found over time which could be explained by better immunosuppressive therapy and improvements in follow-up care. PMID: 28247245 [PubMed - as supplied by publisher]
Source: Netherlands Heart Journal - February 27, 2017 Category: Cardiology Authors: Sammani A, Wind AM, Kirkels JH, Klöpping C, Buijsrogge MP, Ramjakhan FZ, Asselbergs FW, de Jonge N Tags: Neth Heart J Source Type: research

A multicenter study of the impella device for mechanical support of the systemic circulation in pediatric and adolescent patients
ConclusionTemporary circulatory support with Impella devices is feasible in pediatric and adolescent patients, with acceptable risk profiles. More experience and follow up is needed to improve technical performance and patient selection. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 14, 2017 Category: Cardiovascular & Thoracic Surgery Authors: V. Vivian Dimas, Brian H Morray, Dennis W Kim, Christopher SD Almond, Shabana Shahanavaz, Sebastian C Tume, Lynn F Peng, Doff B McElhinney, Henri Justino Tags: Pediatric and Congenital Heart Disease Source Type: research