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Condition: Heart Failure
Drug: Aspirin

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Total 376 results found since Jan 2013.

Clinical Significance of Laboratory-determined Aspirin Poor Responsiveness After Primary Percutaneous Coronary Intervention
Conclusions The majority of APR patients were suitable for tailoring. Neither APR including tailored patients nor AHR were associated with adverse 30-day efficacy or safety clinical outcomes.
Source: Cardiovascular Drugs and Therapy - February 3, 2016 Category: Cardiology Source Type: research

Laboratory assessment of anti-thrombotic therapy in heart failure, atrial fibrillation and coronary artery disease: insights using thrombelastography and a micro-titre plate assay of thrombogenesis and fibrinolysis
Abstract As heart failure, coronary artery disease and atrial fibrillation all bring a risk of thrombosis, anti-thrombotic therapy is recommended. Despite such treatment, major cardiovascular events such as myocardial infarction and stroke still occur, implying inadequate suppression of thrombus formation. Accordingly, identification of patients whose haemostasis remains unimpaired by treatment is valuable. We compared indices for assessing thrombogenesis and fibrinolysis by two different techniques in patients on different anti-thrombotic agents, i.e. aspirin or warfarin. We determined fibrin clot formation and f...
Source: Journal of Thrombosis and Thrombolysis - March 4, 2016 Category: Hematology Source Type: research

Understanding the heart attack gender gap
Imagine someone in the throes of a heart attack. If you pictured a man clutching his chest in agony, that’s understandable. At younger ages, men face a greater risk of heart disease than women. On average, a first heart attack — the most common manifestation of this prevalent disease — strikes men at age 65. For women, the average age of a first heart attack is 72. However, heart disease is the leading cause of death in the United States for both genders. In fact, since 1984, more women have died of heart disease than men each year, although that is partly because women generally live longer than men. So why do middl...
Source: New Harvard Health Information - April 15, 2016 Category: Consumer Health News Authors: Julie Corliss Tags: Health Heart Health Women's Health Source Type: news

3 Drugs with the Most Severe Side Effects
Image Source Drugs have been known to have some sort of side effects on patients. Most of them are not often discussed in the health tabloids. While other drugs have side effects that are very nominal when compared to the benefits the patient derives from their usage, others have side effects that can impact the lives of their users forever. The most common side effects people experience from drug usage are gastrointestinal related issues which include constipation, nausea, and vomiting. Some other drugs can leave you feeling tired and dizzy for a short period of time. Combining these drugs with simple aspirin will usuall...
Source: Healthy Living - The Huffington Post - August 19, 2016 Category: Consumer Health News Source Type: news

Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers.
Conclusions. Concomitant use of NSAIDs or anticoagulants, comorbidities (cerebrovascular disease), and male gender are the most important independent risk factors for ulcer on endoscopy in low-dose aspirin consumers, in a population with a high prevalence of H. pylori infection. PMID: 27579036 [PubMed]
Source: Gastroenterology Research and Practice - September 2, 2016 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

How safe are non-vitamin K antagonist oral anticoagulants in atrial fibrillation?
This article expands on the concept of the ‘net clinical benefit’ and on how this may inform clinical decisions, reinforcing the perception of NOACs as better drugs than VKAs in preventing stroke in AF.
Source: European Journal of Heart Failure Supplements - December 21, 2016 Category: Cardiology Authors: De Caterina, R. Tags: Articles Source Type: research

Current Use of Oral Anticoagulants and Prognostic Analysis in Patients with Atrial Fibrillation Undergoing Coronary Stenting.
CONCLUSIONS: In real-life AF patients undergoing coronary stenting, guideline-recommended VKA was less used. AF patients had adjusted worse prognosis during 12-month follow-up after discharge. It is of utmost importance to improve the current status of oral anticoagulants use. PMID: 28584203 [PubMed - in process]
Source: Chinese Medical Journal - June 7, 2017 Category: General Medicine Authors: Zhai HB, Liu J, Dong ZC, Wang DX, Zhang B Tags: Chin Med J (Engl) Source Type: research

Preoperative Cardiac Evaluation of the Patient Undergoing Noncardiac Surgery
AbstractPurpose of ReviewThis review summarizes selected recent evidence on cardiovascular evaluation before major noncardiac surgery.Recent FindingsBased on recent studies and advancements in coronary stent technology, guidelines now indicate that major noncardiac surgery may be performed sooner (i.e., 3 to 6  months) after drug eluting stent insertion. In addition, contemporary research has emphasized the importance of heart failure, atrial fibrillation, and recent stroke (i.e., prior 9 months) as determinants of perioperative cardiac risk. Biomarkers are taking on increasing importance in preoperativ e cardiac risk st...
Source: Current Anesthesiology Reports - January 26, 2018 Category: Anesthesiology Source Type: research

Aspirin lowers risk of death for patients with diabetes, heart failure
(American College of Cardiology) For people living with both Type 2 diabetes and heart failure, taking an aspirin each day appears to lower the risk of dying or being hospitalized for heart failure, according to research being presented at the American College of Cardiology's 67th Annual Scientific Session. But the data also reveal aspirin use may increase the risk of nonfatal heart attack or stroke, a somewhat contradictory finding that surprised researchers.
Source: EurekAlert! - Medicine and Health - February 28, 2018 Category: International Medicine & Public Health Source Type: news

Daily Aspirin Has Heart Benefits, But Risks Too
The study found the daily pill can reduce the risk for heart failure-related hospitalization and death in people who have both conditions.  However, it also found that a daily aspirin raises their risk for nonfatal heart attack and stroke.
Source: WebMD Health - March 1, 2018 Category: Consumer Health News Source Type: news

Aspirin Linked to Lower Mortality in Diabetes With Heart Failure Aspirin Linked to Lower Mortality in Diabetes With Heart Failure
Researchers were surprised to see a paradoxical increase in nonfatal MI and stroke in parallel with lower mortality with aspirin for primary prevention in patients with diabetes and heart failure.Medscape Medical News
Source: Medscape Medical News Headlines - March 9, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Aspirin lowers risk of death in people with concomitant heart failure and diabetes
Aspirin reduces the risk of  all-cause death or hospitalisation for heart failure in patients with concomitant type 2 diabetes and heart failure but increases the risk of non-fatal heart attack or stroke.
Source: Clinical Pharmacist - June 22, 2018 Category: Drugs & Pharmacology Source Type: research

Scientific expert reaction to Cochrane Review on omega-3 fatty acids
This study provides no evidence to suggest that this dietary advice should change.”Read the press releaseSee the media coverageDeclared interestsProf Tim Chico: “No conflicts.”Dr Ian Johnson: “Ian Johnson has previously held honorary academic appointments in the medical school at the University of East Anglia.”Prof Tom Sanders: “Scientific governor of British Nutrition Foundation, Honorary Director of Nutrition HEART UK.”The Science Media CentreThe Science Media Centre is an independent venture working to promote the voices, stories and views from the scientific community to the news media when science is in ...
Source: Cochrane News and Events - July 17, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Association of early loss of primary functional patency of arteriovenous access with mortality in incident hemodialysis patients: A nationwide population-based observational study
The long-term survival and life quality of hemodialysis (HD) patients depend on adequacy of dialysis via a well-functioning vascular access. Loss of primary functional patency (PFP) of an arteriovenous access (AVA) eventually happens in HD patients. The association between time to loss of PFP of AVAs and mortality in HD patients remains unclear. The retrospective nationwide population-based cohort study compared the hazards of mortality with time to loss of PFP. We enrolled 1618 adult incident HD patients who received HD via AVAs for at least 90 days between January 1, 2001 and December 31, 2013. They were divided into ear...
Source: Medicine - August 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

How can the results of the COMPASS trial benefit patients with coronary or peripheral artery disease in Poland.
Abstract Aspirin decreases the risk of recurrent thrombotic events in patients with coronary artery disease or peripheral artery disease but the risk of recurrent events remains high. Long term dual antiplatelet therapy or the combination of aspirin and warfarin further reduces the risk of recurrent events, but at the cost of increased bleeding and neither of these treatments reduce mortality. The Cardiovascular OutcoMes in People using Anticoagulation StrategieS randomised controlled trial involving 27,395 patients from 602 sites in 33 countries (Poland: 9 sites, 518 patients) tested whether low-dose anticoagulan...
Source: Polish Heart Journal - May 29, 2019 Category: Cardiology Authors: Kruger PC, Guzik TJ, Eikelboom JW Tags: Kardiol Pol Source Type: research