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The Effects of Intelectin-1 on Antioxidant and Angiogenesis in HUVECs Exposed to Oxygen Glucose Deprivation
Conclusion: These results suggest intelectin-1 promotes angiogenesis, inhibits oxidative stress and reduces apoptosis by stimulating the Akt-eNOS signaling pathway in response to ischemia in vitro. Introduction Stroke is a main reason of human neurological disability, ischemic stroke (IS) accounts for almost 80–90% of all strokes. IS occurs after a cerebral blood flow disruption, leading to cellular death and tissue damage by restricting glucose and oxygen supplies (1). Ischemic vascular diseases cause substantial vascular valve and vascular endothelial cell injuries, eventually damaging the surrounding tis...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Loneliness Can Actually Hurt Your Heart. Here ’s Why
Research has shown, again and again, that emotional and physical health are inextricably linked. There are significant health benefits associated with love and friendship, supportive marriages and feelings of gratitude, for example. And there are significant health risks linked to the opposite. A new study, published Monday in the journal Heart, looked at social isolation (being separated from other people) and loneliness (being cut off from social connection, and being unhappy about it). Researchers found that people who are socially isolated or lonely are more likely to have a heart attack or stroke, compared to people w...
Source: TIME: Health - March 26, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime Research Source Type: news

Lost individual income due to severe health events: life-course perspective in the Northern Finland Birth Cohort 1966
CONCLUSIONS: Stroke and heart attack but not cancer have exogenous deleterious effects on individual economy, independently of early-life factors. The effects accelerate by time. Negative income trend in control men shows that severe health events do not explain all decrease in income.PMID:36040214 | DOI:10.1093/eurpub/ckac110
Source: Cancer Control - August 30, 2022 Category: Cancer & Oncology Authors: Ina Rissanen Iiro Nerg Leena Ala-Mursula Marko Korhonen Source Type: research

Pre-eclampsia and cardiovascular risk: a long-term nationwide cohort study on over 120 000 Finnish women
Conclusion Pre-eclampsia-related significant elevations in CVD risks of Finnish women with inherently high risk for these diseases were of the same magnitude as reported previously from other countries. Thus, women with a history of pre-eclampsia should be screened and treated early for modifiable cardiovascular risk factors.
Source: BMJ Open - December 22, 2022 Category: General Medicine Authors: Venetkoski, M., Joensuu, J., Gissler, M., Ylikorkala, O., Mikkola, T. S., Savolainen-Peltonen, H. Tags: Open access Obstetrics and gynaecology Source Type: research

Country of birth and mortality risk in hypertension with and without diabetes: the Swedish primary care cardiovascular database
Conclusion: In Sweden, hypertensive immigrants (with the exception for Finnish-born) with and without diabetes have a mortality advantage, as compared to Swedish-born.
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Nurse-staffing level and quality of acute care services: Evidence from cross-national panel data analysis in OECD countries
ConclusionA higher proportion of nurses-staffing level is associated with better performance of acute care services in OECD countries. Also, the nursing characteristics of Sweden, Denmark, Canada, Netherlands, Finland, Switzerland, Australia and United States would be good patterns for other countries to maximize nursing outcomes in the care of patients with acute and life-threatening conditions by reducing the risk of complication, mortality and adverse clinical outcomes.
Source: International Journal of Nursing Sciences - December 5, 2018 Category: Nursing Source Type: research

Sex-based outcomes after coronary artery bypass grafting.
CONCLUSIONS: Sex was not an independent predictor of long-term MACE after CABG in this population-based cohort study. Men had however higher long-term all-cause mortality and women higher risk of myocardial infarction. Long-term outcomes should be accounted for when considering sex as a risk factor for CABG. PMID: 33484674 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - January 20, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Kytö V, Sipilä J, Tornio A, Rautava P, Gunn J Tags: Ann Thorac Surg Source Type: research

Patients with rheumatoid arthritis have impaired long-term outcomes after myocardial infarction: a nationwide case-control registry study
ConclusionRA is independently associated with poorer prognosis after MI. RA duration and corticosteroid usage and dosage were independent predictors of mortality after MI in RA. Special attention is needed for improvement of outcomes after MI in this vulnerable population.
Source: Rheumatology - March 1, 2021 Category: Rheumatology Source Type: research

Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study
Diabetes Metab. 2023 Jan 3:101418. doi: 10.1016/j.diabet.2022.101418. Online ahead of print.ABSTRACTBACKGROUND: Continued expansion of indications for sodium-glucose cotransporter-2 inhibitors increases importance of evaluating cardiovascular and kidney efficacy and safety of empagliflozin in patients with type 2 diabetes compared to similar therapies.METHODS: The EMPRISE Europe and Asia study is a non-interventional cohort study using data from 2014-2019 in seven European (Denmark, Finland, Germany, Norway, Spain, Sweden, United Kingdom) and four Asian (Israel, Japan, South Korea, Taiwan) countries. Patients with type 2 d...
Source: Diabetes and Metabolism - January 7, 2023 Category: Endocrinology Authors: Avraham Karasik Stefanie Lanzinger Elise Chia-Hui Tan Daisuke Yabe Dae Jung Kim Wayne H-H Sheu Cheli Melzer-Cohen Reinhard W Holl Kyoung Hwa Ha Kamlesh Khunti Francesco Zaccardi Anuradhaa Subramanian Krishnarajah Nirantharakumar Thomas Nystr öm Leo Niska Source Type: research

Choice of the first anti-epileptic drug in elderly patients with newly diagnosed epilepsy: A Finnish retrospective study
Conclusion First-generation AEDs are still the most commonly employed first drugs for elderly patients with newly diagnosed epilepsy in Finland. Age and comorbid conditions have an effect in the choice of the initial AED treatment.
Source: Seizure - July 5, 2015 Category: Neurology Source Type: research

Regional trends in avoidable hospitalisations due to complications among population with diabetes in Finland in 1996-2011: a register-based cohort study
Conclusions Our study suggests that the prevention of complications among persons with diabetes has improved in Finland between 1996 and 2011. The results further suggest that the prevention of complications has become more uniform throughout the country.
Source: BMJ Open - August 21, 2016 Category: Journals (General) Authors: Manderbacka, K., Arffman, M., Lumme, S., Lehikoinen, M., Winell, K., Keskimäki, I. Tags: Open access, Health services research, Diabetes and Endocrinology Source Type: research

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