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Guidelines for the Management of Atopic Dermatitis in Children: A Systematic Review
Conclusions: Most guidelines were recommended for use with revision. No significant changes were observed in the primary management of atopic dermatitis in children compared to previous evidence. New biological agents and complementary alternative medicine are increasingly available, but the evidence for the treatment of atopic dermatitis in children is still limited.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - November 2, 2022 Category: Allergy & Immunology Source Type: research

Prevalence and Risk Factors for Allergic Rhinitis in China: A Systematic Review and Meta-Analysis
Evid Based Complement Alternat Med. 2022 Sep 23;2022:7165627. doi: 10.1155/2022/7165627. eCollection 2022.ABSTRACTThe prevalence of allergic rhinitis (AR) has increased tremendously in the recent year in China. Evidence-based medicine to objectively evaluate the prevalence and risk factors for AR in China is urgently required. Toward this, we systematically searched four English and four Chinese databases to identify the literature on the same, from the year of website establishment until November 2021. A total of 51 studies were evaluated, and data were obtained through Stata 16 analysis. Overall pooled risk factors for a...
Source: Evidence-based Complementary and Alternative Medicine - October 4, 2022 Category: Complementary Medicine Authors: Kaiyun Pang Guodong Li Mouhan Li Lan Zhang Qinwei Fu Kepu Liu Wei Zheng Zhiqiao Wang Juan Zhong Lijin Lu Peijia Li Yucan Zhou Wanling Zhang Qinxiu Zhang Source Type: research

Qingpeng Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules for Its Antipruritic Effects in Experimental Allergic Contact Dermatitis
Conclusion Via a HPLC system and a BATMAN-TCM platform, for the first time we performed detailed HPLC fingerprint analysis and network pharmacology studies of QP ointment. By in-depth animal and molecular analysis, we identified a number of chronic dermatitis-associated Th1/2 cytokines, itch mediators, and cellular signaling pathways in the skin, DRG and serum for QP to treat the inflammation and chronic itch associated with ACD. Our data clearly suggested, upon stimulation, cytokines and itch-related mediators are released from the skin and neuronal tissues, and QP could effectively work on both the skin and sensory neur...
Source: Frontiers in Pharmacology - April 8, 2019 Category: Drugs & Pharmacology Source Type: research

Effect of traditional Chinese medicine on skin lesions and quality of life in patients with moderate to severe eczema
We report a case series of 14 patients with AD treated with this approach and analyses of the TCM herbs in murine and in vitro models.
Source: Annals of Allergy, Asthma and Immunology - March 9, 2018 Category: Allergy & Immunology Authors: Erin Thanik, Julia A. Wisniewski, Anna Nowak-Wegrzyn, Hugh Sampson, Xiu-Min Li Source Type: research

Improvement of skin lesions and life quality in moderate-to-severe eczema patients by combined TCM therapy
We report a case series of 14 AD patients treated with this approach and analysis of the TCM herbs in murine and in vitro models.
Source: Annals of Allergy, Asthma and Immunology - March 9, 2018 Category: Allergy & Immunology Authors: Erin Thanik, Julia A. Wisniewski, Anna Nowak-Wegrzyn, Hugh Sampson, Xiu-Min Li Tags: Letter Source Type: research

Complementary, alternative and integrative medicine for childhood atopic dermatitis.
CONCLUSIONS: AD is a complex disease. The psychodynamics of the child and his/her family is the reason for the often suboptimal outcomes. Both Western and CAM practitioners should collaborate to create a mutually encouraging environment for the advances of IM. CAM and IM publications and patents are reviewed. Evidence of their efficacy is generally lacking. Further research is needed. PMID: 29189188 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - December 3, 2017 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Eczema therapeutics in children: what do the clinical trials say?
Abstract Eczema or atopic dermatitis is a common childhood atopic disease associated with chronicity and impaired quality of life. As there is no cure for the disease, treatment relies on topical and systemic anti-allergic or immunomodulating therapies. Topical corticosteroid, macrolide immunosuppressants, and oral immunomodulating drugs for recalcitrant disease have been the mainstay of therapy. Management of atopic dermatitis must consider the individual symptomatic variability of the disease. Basic therapy is focused on patient/family education, hydrating topical treatment, and avoidance of specific and non-spe...
Source: Hong Kong Med J - April 23, 2015 Category: Journals (General) Authors: Leung TN, Hon KL Tags: Hong Kong Med J Source Type: research